| Full name: ectonucleotide pyrophosphatase/phosphodiesterase family member 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 59084 | HGNC ID: HGNC:13717 | Ensembl Gene: ENSG00000112796 | OMIM ID: 617001 |
| Drug and gene relationship at DGIdb | |||
Expression of ENPP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENPP5 | 59084 | 227803_at | 0.1657 | 0.9231 | |
| GSE26886 | ENPP5 | 59084 | 237054_at | 1.2074 | 0.0254 | |
| GSE45670 | ENPP5 | 59084 | 227803_at | -0.7098 | 0.2452 | |
| GSE53622 | ENPP5 | 59084 | 20084 | -0.2316 | 0.3809 | |
| GSE53624 | ENPP5 | 59084 | 20084 | -0.1507 | 0.5023 | |
| GSE63941 | ENPP5 | 59084 | 227803_at | -2.6450 | 0.0876 | |
| GSE77861 | ENPP5 | 59084 | 227803_at | 0.2176 | 0.3101 | |
| GSE97050 | ENPP5 | 59084 | A_23_P214244 | -0.0378 | 0.8879 | |
| SRP007169 | ENPP5 | 59084 | RNAseq | 0.6613 | 0.3597 | |
| SRP064894 | ENPP5 | 59084 | RNAseq | 0.3025 | 0.3760 | |
| SRP133303 | ENPP5 | 59084 | RNAseq | 0.4597 | 0.3514 | |
| SRP159526 | ENPP5 | 59084 | RNAseq | 1.4521 | 0.0464 | |
| SRP193095 | ENPP5 | 59084 | RNAseq | 0.6182 | 0.0486 | |
| SRP219564 | ENPP5 | 59084 | RNAseq | -0.2381 | 0.7100 | |
| TCGA | ENPP5 | 59084 | RNAseq | -0.9697 | 0.0052 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ENPP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENPP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENPP5 | 59084 | 6 | 2 | 22 | |
| GSE20123 | ENPP5 | 59084 | 6 | 2 | 22 | |
| GSE43470 | ENPP5 | 59084 | 6 | 0 | 37 | |
| GSE46452 | ENPP5 | 59084 | 2 | 10 | 47 | |
| GSE47630 | ENPP5 | 59084 | 7 | 5 | 28 | |
| GSE54993 | ENPP5 | 59084 | 3 | 1 | 66 | |
| GSE54994 | ENPP5 | 59084 | 8 | 3 | 42 | |
| GSE60625 | ENPP5 | 59084 | 0 | 3 | 8 | |
| GSE74703 | ENPP5 | 59084 | 6 | 0 | 30 | |
| GSE74704 | ENPP5 | 59084 | 2 | 1 | 17 | |
| TCGA | ENPP5 | 59084 | 18 | 14 | 64 |
Total number of gains: 64; Total number of losses: 41; Total Number of normals: 383.
Somatic mutations of ENPP5:
Generating mutation plots.
Highly correlated genes for ENPP5:
Showing top 20/269 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENPP5 | FADD | 0.755483 | 3 | 0 | 3 |
| ENPP5 | UBTD2 | 0.745882 | 3 | 0 | 3 |
| ENPP5 | TLE2 | 0.741524 | 3 | 0 | 3 |
| ENPP5 | PUF60 | 0.730479 | 3 | 0 | 3 |
| ENPP5 | BCL2L11 | 0.728664 | 3 | 0 | 3 |
| ENPP5 | CCDC97 | 0.726096 | 3 | 0 | 3 |
| ENPP5 | HNRNPA0 | 0.723971 | 3 | 0 | 3 |
| ENPP5 | CACNA1B | 0.723791 | 3 | 0 | 3 |
| ENPP5 | NEURL1B | 0.723214 | 3 | 0 | 3 |
| ENPP5 | TBCC | 0.715962 | 3 | 0 | 3 |
| ENPP5 | ALG10 | 0.710318 | 3 | 0 | 3 |
| ENPP5 | ZNF419 | 0.709823 | 3 | 0 | 3 |
| ENPP5 | PPFIA1 | 0.709344 | 3 | 0 | 3 |
| ENPP5 | ASPSCR1 | 0.708844 | 3 | 0 | 3 |
| ENPP5 | TRIM38 | 0.705434 | 3 | 0 | 3 |
| ENPP5 | ZNF566 | 0.704915 | 3 | 0 | 3 |
| ENPP5 | WBP4 | 0.698665 | 3 | 0 | 3 |
| ENPP5 | RNF19A | 0.697691 | 3 | 0 | 3 |
| ENPP5 | BABAM1 | 0.695228 | 3 | 0 | 3 |
| ENPP5 | CSNK1D | 0.693218 | 3 | 0 | 3 |
For details and further investigation, click here
