| Full name: neuralized E3 ubiquitin protein ligase 1B | Alias Symbol: DKFZP761M1511|Neur2|RNF67B | ||
| Type: protein-coding gene | Cytoband: 5q35.1 | ||
| Entrez ID: 54492 | HGNC ID: HGNC:35422 | Ensembl Gene: ENSG00000214357 | OMIM ID: 615893 |
| Drug and gene relationship at DGIdb | |||
Expression of NEURL1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEURL1B | 54492 | 225355_at | 0.4068 | 0.3104 | |
| GSE26886 | NEURL1B | 54492 | 225355_at | -0.3435 | 0.1956 | |
| GSE45670 | NEURL1B | 54492 | 225355_at | -0.2791 | 0.1636 | |
| GSE53622 | NEURL1B | 54492 | 24044 | -0.7352 | 0.0000 | |
| GSE53624 | NEURL1B | 54492 | 24044 | -0.1279 | 0.1481 | |
| GSE63941 | NEURL1B | 54492 | 225355_at | 1.8689 | 0.0085 | |
| GSE77861 | NEURL1B | 54492 | 225355_at | 0.4838 | 0.2570 | |
| GSE97050 | NEURL1B | 54492 | A_32_P198731 | 0.0446 | 0.8735 | |
| SRP007169 | NEURL1B | 54492 | RNAseq | 0.4455 | 0.4771 | |
| SRP008496 | NEURL1B | 54492 | RNAseq | 0.2519 | 0.5166 | |
| SRP064894 | NEURL1B | 54492 | RNAseq | 0.0749 | 0.7706 | |
| SRP133303 | NEURL1B | 54492 | RNAseq | -0.3919 | 0.1081 | |
| SRP159526 | NEURL1B | 54492 | RNAseq | -0.0239 | 0.9436 | |
| SRP193095 | NEURL1B | 54492 | RNAseq | 0.3973 | 0.0365 | |
| SRP219564 | NEURL1B | 54492 | RNAseq | 0.1679 | 0.6139 | |
| TCGA | NEURL1B | 54492 | RNAseq | 0.1566 | 0.0855 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NEURL1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEURL1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEURL1B | 54492 | 2 | 13 | 15 | |
| GSE20123 | NEURL1B | 54492 | 2 | 13 | 15 | |
| GSE43470 | NEURL1B | 54492 | 1 | 10 | 32 | |
| GSE46452 | NEURL1B | 54492 | 0 | 27 | 32 | |
| GSE47630 | NEURL1B | 54492 | 0 | 20 | 20 | |
| GSE54993 | NEURL1B | 54492 | 9 | 2 | 59 | |
| GSE54994 | NEURL1B | 54492 | 2 | 15 | 36 | |
| GSE60625 | NEURL1B | 54492 | 1 | 0 | 10 | |
| GSE74703 | NEURL1B | 54492 | 1 | 7 | 28 | |
| GSE74704 | NEURL1B | 54492 | 1 | 6 | 13 | |
| TCGA | NEURL1B | 54492 | 8 | 34 | 54 |
Total number of gains: 27; Total number of losses: 147; Total Number of normals: 314.
Somatic mutations of NEURL1B:
Generating mutation plots.
Highly correlated genes for NEURL1B:
Showing top 20/299 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEURL1B | PANK4 | 0.748047 | 3 | 0 | 3 |
| NEURL1B | DENND4B | 0.742003 | 3 | 0 | 3 |
| NEURL1B | MSL2 | 0.726421 | 3 | 0 | 3 |
| NEURL1B | ENPP5 | 0.723214 | 3 | 0 | 3 |
| NEURL1B | CRTC2 | 0.71689 | 3 | 0 | 3 |
| NEURL1B | EHMT2 | 0.714952 | 3 | 0 | 3 |
| NEURL1B | INTS3 | 0.713154 | 4 | 0 | 4 |
| NEURL1B | UROS | 0.713151 | 3 | 0 | 3 |
| NEURL1B | UBR7 | 0.709784 | 3 | 0 | 3 |
| NEURL1B | XAB2 | 0.709312 | 3 | 0 | 3 |
| NEURL1B | COX15 | 0.706816 | 3 | 0 | 3 |
| NEURL1B | UNC119B | 0.703775 | 3 | 0 | 3 |
| NEURL1B | USP22 | 0.70375 | 3 | 0 | 3 |
| NEURL1B | DDX18 | 0.703065 | 3 | 0 | 3 |
| NEURL1B | ANKZF1 | 0.70231 | 3 | 0 | 3 |
| NEURL1B | NEK3 | 0.701987 | 3 | 0 | 3 |
| NEURL1B | PRDM15 | 0.699003 | 3 | 0 | 3 |
| NEURL1B | GNB1 | 0.695843 | 3 | 0 | 3 |
| NEURL1B | PTPRJ | 0.69395 | 4 | 0 | 4 |
| NEURL1B | TMED8 | 0.692895 | 3 | 0 | 3 |
For details and further investigation, click here
