BABAM1

 

Full name: BRISC and BRCA1 A complex member 1 Alias Symbol: FLJ20571|HSPC142|NBA1|MERIT40
Type: protein-coding gene Cytoband: 19p13.11
Entrez ID: 29086 HGNC ID: HGNC:25008 Ensembl Gene: ENSG00000105393 OMIM ID: 612766
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of BABAM1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BABAM1 29086 221711_s_at 0.2615 0.6151
GSE20347 BABAM1 29086 221711_s_at 0.0923 0.5054
GSE23400 BABAM1 29086 221711_s_at 0.1988 0.0003
GSE26886 BABAM1 29086 221711_s_at -0.1063 0.6405
GSE29001 BABAM1 29086 221711_s_at 0.3260 0.3232
GSE38129 BABAM1 29086 221711_s_at 0.1222 0.3399
GSE45670 BABAM1 29086 221711_s_at 0.2118 0.0773
GSE53622 BABAM1 29086 6558 -0.0189 0.8413
GSE53624 BABAM1 29086 6558 0.2686 0.0000
GSE63941 BABAM1 29086 221711_s_at 0.2780 0.4514
GSE77861 BABAM1 29086 221711_s_at 0.2965 0.1039
GSE97050 BABAM1 29086 A_23_P119714 -0.1561 0.6270
SRP007169 BABAM1 29086 RNAseq 0.0227 0.9539
SRP008496 BABAM1 29086 RNAseq 0.1950 0.4389
SRP064894 BABAM1 29086 RNAseq 0.4630 0.0943
SRP133303 BABAM1 29086 RNAseq 0.2115 0.1098
SRP159526 BABAM1 29086 RNAseq 0.0333 0.8773
SRP193095 BABAM1 29086 RNAseq 0.1035 0.2480
SRP219564 BABAM1 29086 RNAseq 0.2938 0.3747

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by BABAM1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of BABAM1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BABAM1 29086 4 4 22
GSE20123 BABAM1 29086 3 2 25
GSE43470 BABAM1 29086 2 6 35
GSE46452 BABAM1 29086 47 1 11
GSE47630 BABAM1 29086 4 8 28
GSE54993 BABAM1 29086 15 4 51
GSE54994 BABAM1 29086 6 14 33
GSE60625 BABAM1 29086 9 0 2
GSE74703 BABAM1 29086 2 4 30
GSE74704 BABAM1 29086 0 2 18
TCGA BABAM1 29086 17 9 70

Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.  


 

Somatic mutations of BABAM1:

 

Generating mutation plots.

 

Highly correlated genes for BABAM1:

 

Showing top 20/1016 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BABAM1EXOC60.816668303
BABAM1TNFRSF1A0.797778303
BABAM1CD99L20.780095303
BABAM1MKNK10.774984303
BABAM1KRTCAP20.764617303
BABAM1ATG4C0.760529303
BABAM1ASH2L0.751948303
BABAM1RUNDC10.75014404
BABAM1UPF3B0.742652303
BABAM1PPP1R350.741785303
BABAM1CSRNP20.739008303
BABAM1C11orf490.729965303
BABAM1B9D20.726787404
BABAM1DHX400.717817404
BABAM1NDUFA80.717362303
BABAM1PRPSAP20.714769303
BABAM1PLEKHJ10.714037303
BABAM1PELI20.713539303
BABAM1ZNF7000.712479303
BABAM1KTI120.712302303

For details and further investigation, click here