| Full name: PTPRF interacting protein alpha 1 | Alias Symbol: LIP.1|LIPRIN | ||
| Type: protein-coding gene | Cytoband: 11q13.3 | ||
| Entrez ID: 8500 | HGNC ID: HGNC:9245 | Ensembl Gene: ENSG00000131626 | OMIM ID: 611054 |
| Drug and gene relationship at DGIdb | |||
Expression of PPFIA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPFIA1 | 8500 | 202066_at | 1.6286 | 0.1337 | |
| GSE20347 | PPFIA1 | 8500 | 202066_at | 1.9297 | 0.0000 | |
| GSE23400 | PPFIA1 | 8500 | 202066_at | 1.2832 | 0.0000 | |
| GSE26886 | PPFIA1 | 8500 | 202066_at | 2.6923 | 0.0000 | |
| GSE29001 | PPFIA1 | 8500 | 202066_at | 1.7147 | 0.0003 | |
| GSE38129 | PPFIA1 | 8500 | 202066_at | 1.8505 | 0.0000 | |
| GSE45670 | PPFIA1 | 8500 | 202066_at | 1.0029 | 0.0100 | |
| GSE53622 | PPFIA1 | 8500 | 106241 | 1.3261 | 0.0000 | |
| GSE53624 | PPFIA1 | 8500 | 53561 | 1.6440 | 0.0000 | |
| GSE63941 | PPFIA1 | 8500 | 202066_at | 0.6780 | 0.3983 | |
| GSE77861 | PPFIA1 | 8500 | 202066_at | 1.6078 | 0.0597 | |
| GSE97050 | PPFIA1 | 8500 | A_23_P302116 | 1.5231 | 0.1287 | |
| SRP007169 | PPFIA1 | 8500 | RNAseq | 2.6624 | 0.0005 | |
| SRP008496 | PPFIA1 | 8500 | RNAseq | 2.9086 | 0.0001 | |
| SRP064894 | PPFIA1 | 8500 | RNAseq | 1.9300 | 0.0000 | |
| SRP133303 | PPFIA1 | 8500 | RNAseq | 2.2868 | 0.0000 | |
| SRP159526 | PPFIA1 | 8500 | RNAseq | 3.4560 | 0.0000 | |
| SRP193095 | PPFIA1 | 8500 | RNAseq | 2.4938 | 0.0000 | |
| SRP219564 | PPFIA1 | 8500 | RNAseq | 2.1808 | 0.0002 | |
| TCGA | PPFIA1 | 8500 | RNAseq | 0.3808 | 0.0001 |
Upregulated datasets: 15; Downregulated datasets: 0.
Survival by PPFIA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPFIA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPFIA1 | 8500 | 20 | 1 | 9 | |
| GSE20123 | PPFIA1 | 8500 | 20 | 1 | 9 | |
| GSE43470 | PPFIA1 | 8500 | 14 | 2 | 27 | |
| GSE46452 | PPFIA1 | 8500 | 32 | 3 | 24 | |
| GSE47630 | PPFIA1 | 8500 | 18 | 2 | 20 | |
| GSE54993 | PPFIA1 | 8500 | 1 | 24 | 45 | |
| GSE54994 | PPFIA1 | 8500 | 25 | 5 | 23 | |
| GSE60625 | PPFIA1 | 8500 | 0 | 8 | 3 | |
| GSE74703 | PPFIA1 | 8500 | 11 | 1 | 24 | |
| GSE74704 | PPFIA1 | 8500 | 13 | 0 | 7 | |
| TCGA | PPFIA1 | 8500 | 64 | 3 | 29 |
Total number of gains: 218; Total number of losses: 50; Total Number of normals: 220.
Somatic mutations of PPFIA1:
Generating mutation plots.
Highly correlated genes for PPFIA1:
Showing top 20/1511 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPFIA1 | FADD | 0.90905 | 11 | 0 | 11 |
| PPFIA1 | ANO1 | 0.79142 | 13 | 0 | 13 |
| PPFIA1 | A4GALT | 0.767764 | 3 | 0 | 3 |
| PPFIA1 | KIAA0895 | 0.749286 | 4 | 0 | 4 |
| PPFIA1 | SPSB2 | 0.732038 | 3 | 0 | 3 |
| PPFIA1 | HES4 | 0.712852 | 3 | 0 | 3 |
| PPFIA1 | ENPP5 | 0.709344 | 3 | 0 | 3 |
| PPFIA1 | CTTN | 0.709029 | 12 | 0 | 10 |
| PPFIA1 | HOXB7 | 0.698584 | 11 | 0 | 10 |
| PPFIA1 | NEK6 | 0.698458 | 3 | 0 | 3 |
| PPFIA1 | SMIM8 | 0.692929 | 4 | 0 | 4 |
| PPFIA1 | MRPL21 | 0.686663 | 9 | 0 | 9 |
| PPFIA1 | CENPA | 0.684108 | 9 | 0 | 8 |
| PPFIA1 | TPCN2 | 0.682024 | 9 | 0 | 9 |
| PPFIA1 | ASB7 | 0.681647 | 3 | 0 | 3 |
| PPFIA1 | CD276 | 0.68161 | 4 | 0 | 4 |
| PPFIA1 | PLXNA1 | 0.679396 | 11 | 0 | 11 |
| PPFIA1 | HPS3 | 0.677929 | 5 | 0 | 4 |
| PPFIA1 | OPA1 | 0.677885 | 6 | 0 | 5 |
| PPFIA1 | TNPO2 | 0.677614 | 3 | 0 | 3 |
For details and further investigation, click here
