| Full name: WW domain binding protein 4 | Alias Symbol: FBP21|MGC117310 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 11193 | HGNC ID: HGNC:12739 | Ensembl Gene: ENSG00000120688 | OMIM ID: 604981 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of WBP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WBP4 | 11193 | 203599_s_at | -0.6304 | 0.1719 | |
| GSE20347 | WBP4 | 11193 | 203597_s_at | -0.5529 | 0.0007 | |
| GSE23400 | WBP4 | 11193 | 203599_s_at | -0.0422 | 0.5155 | |
| GSE26886 | WBP4 | 11193 | 203598_s_at | 0.3991 | 0.2795 | |
| GSE29001 | WBP4 | 11193 | 203597_s_at | -0.3836 | 0.3927 | |
| GSE38129 | WBP4 | 11193 | 203597_s_at | -0.4977 | 0.0019 | |
| GSE45670 | WBP4 | 11193 | 203598_s_at | 0.0045 | 0.9832 | |
| GSE53622 | WBP4 | 11193 | 75231 | -0.3338 | 0.0000 | |
| GSE53624 | WBP4 | 11193 | 75231 | -0.0941 | 0.1327 | |
| GSE63941 | WBP4 | 11193 | 203598_s_at | -0.4500 | 0.1855 | |
| GSE77861 | WBP4 | 11193 | 203598_s_at | 0.0671 | 0.8031 | |
| GSE97050 | WBP4 | 11193 | A_23_P140035 | -0.4502 | 0.1774 | |
| SRP007169 | WBP4 | 11193 | RNAseq | -0.2618 | 0.6748 | |
| SRP064894 | WBP4 | 11193 | RNAseq | 0.0743 | 0.6545 | |
| SRP133303 | WBP4 | 11193 | RNAseq | -0.3048 | 0.1304 | |
| SRP159526 | WBP4 | 11193 | RNAseq | -0.5657 | 0.0018 | |
| SRP193095 | WBP4 | 11193 | RNAseq | -0.2811 | 0.0179 | |
| SRP219564 | WBP4 | 11193 | RNAseq | -0.6617 | 0.1223 | |
| TCGA | WBP4 | 11193 | RNAseq | -0.1127 | 0.0818 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WBP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WBP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WBP4 | 11193 | 0 | 15 | 15 | |
| GSE20123 | WBP4 | 11193 | 0 | 14 | 16 | |
| GSE43470 | WBP4 | 11193 | 3 | 13 | 27 | |
| GSE46452 | WBP4 | 11193 | 0 | 33 | 26 | |
| GSE47630 | WBP4 | 11193 | 2 | 27 | 11 | |
| GSE54993 | WBP4 | 11193 | 12 | 2 | 56 | |
| GSE54994 | WBP4 | 11193 | 1 | 16 | 36 | |
| GSE60625 | WBP4 | 11193 | 0 | 3 | 8 | |
| GSE74703 | WBP4 | 11193 | 3 | 10 | 23 | |
| GSE74704 | WBP4 | 11193 | 0 | 11 | 9 | |
| TCGA | WBP4 | 11193 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 184; Total Number of normals: 276.
Somatic mutations of WBP4:
Generating mutation plots.
Highly correlated genes for WBP4:
Showing top 20/574 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WBP4 | SLMAP | 0.836127 | 3 | 0 | 3 |
| WBP4 | ANGPTL1 | 0.794274 | 3 | 0 | 3 |
| WBP4 | HOXA4 | 0.793433 | 3 | 0 | 3 |
| WBP4 | BVES | 0.791651 | 3 | 0 | 3 |
| WBP4 | LSM11 | 0.785439 | 4 | 0 | 4 |
| WBP4 | RAB9B | 0.783136 | 3 | 0 | 3 |
| WBP4 | NKIRAS1 | 0.782327 | 3 | 0 | 3 |
| WBP4 | XKR4 | 0.778603 | 3 | 0 | 3 |
| WBP4 | ANO5 | 0.775203 | 3 | 0 | 3 |
| WBP4 | KHNYN | 0.765945 | 3 | 0 | 3 |
| WBP4 | C5orf24 | 0.756247 | 3 | 0 | 3 |
| WBP4 | RBPMS2 | 0.75466 | 3 | 0 | 3 |
| WBP4 | LRFN5 | 0.75117 | 3 | 0 | 3 |
| WBP4 | FNDC5 | 0.749813 | 3 | 0 | 3 |
| WBP4 | MAMDC2 | 0.748154 | 3 | 0 | 3 |
| WBP4 | ZNF358 | 0.738129 | 3 | 0 | 3 |
| WBP4 | SUGP2 | 0.734633 | 3 | 0 | 3 |
| WBP4 | RPL14 | 0.734024 | 3 | 0 | 3 |
| WBP4 | ASB5 | 0.731444 | 4 | 0 | 4 |
| WBP4 | SORCS1 | 0.729211 | 4 | 0 | 4 |
For details and further investigation, click here
