TRIM38

 

Full name: tripartite motif containing 38 Alias Symbol: RORET
Type: protein-coding gene Cytoband: 6p22.2
Entrez ID: 10475 HGNC ID: HGNC:10059 Ensembl Gene: ENSG00000112343 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TRIM38:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIM38 10475 203568_s_at -0.0537 0.9352
GSE20347 TRIM38 10475 203568_s_at -0.3395 0.0807
GSE23400 TRIM38 10475 203567_s_at -0.3140 0.0001
GSE26886 TRIM38 10475 203567_s_at -1.0116 0.0003
GSE29001 TRIM38 10475 203567_s_at -0.3319 0.2269
GSE38129 TRIM38 10475 203568_s_at -0.2447 0.0898
GSE45670 TRIM38 10475 203567_s_at -0.0366 0.9025
GSE53622 TRIM38 10475 89914 -0.3101 0.0004
GSE53624 TRIM38 10475 89914 -0.3742 0.0000
GSE63941 TRIM38 10475 203568_s_at -1.0825 0.1959
GSE77861 TRIM38 10475 235084_x_at 0.2610 0.4363
GSE97050 TRIM38 10475 A_24_P294851 -0.1369 0.6950
SRP007169 TRIM38 10475 RNAseq -0.0994 0.7743
SRP008496 TRIM38 10475 RNAseq -0.4298 0.0429
SRP064894 TRIM38 10475 RNAseq -0.3318 0.0530
SRP133303 TRIM38 10475 RNAseq -0.4012 0.0053
SRP159526 TRIM38 10475 RNAseq -0.6875 0.0603
SRP193095 TRIM38 10475 RNAseq -0.3865 0.0033
SRP219564 TRIM38 10475 RNAseq -0.5118 0.3140
TCGA TRIM38 10475 RNAseq -0.0122 0.8620

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by TRIM38 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TRIM38:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIM38 10475 4 2 24
GSE20123 TRIM38 10475 4 2 24
GSE43470 TRIM38 10475 5 0 38
GSE46452 TRIM38 10475 1 9 49
GSE47630 TRIM38 10475 8 5 27
GSE54993 TRIM38 10475 1 1 68
GSE54994 TRIM38 10475 10 4 39
GSE60625 TRIM38 10475 0 1 10
GSE74703 TRIM38 10475 5 0 31
GSE74704 TRIM38 10475 0 1 19
TCGA TRIM38 10475 14 21 61

Total number of gains: 52; Total number of losses: 46; Total Number of normals: 390.  


 

Somatic mutations of TRIM38:

 

Generating mutation plots.

 

Highly correlated genes for TRIM38:

 

Showing top 20/182 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIM38ITPRIPL20.738876303
TRIM38CDK5RAP30.724695303
TRIM38PUS7L0.724222303
TRIM38ZNF6810.722969303
TRIM38ZNF920.718359303
TRIM38ZNF2560.713039303
TRIM38GDAP20.708048303
TRIM38ENPP50.705434303
TRIM38ZNF5140.702979303
TRIM38SENP60.702791303
TRIM38ZNF8000.692474303
TRIM38CCNYL10.690394303
TRIM38SMARCA40.688538303
TRIM38NAT10.687055303
TRIM38TTC170.680135403
TRIM38TAF9B0.675284303
TRIM38ZNF1950.675249303
TRIM38GALNT110.666907303
TRIM38ZNF75A0.661295403
TRIM38SYTL20.659603303

For details and further investigation, click here