| Full name: ectonucleotide pyrophosphatase/phosphodiesterase 7 | Alias Symbol: alk-SMase|NPP7 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 339221 | HGNC ID: HGNC:23764 | Ensembl Gene: ENSG00000182156 | OMIM ID: 616997 |
| Drug and gene relationship at DGIdb | |||
Expression of ENPP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENPP7 | 339221 | 238245_at | 0.3876 | 0.0739 | |
| GSE26886 | ENPP7 | 339221 | 238245_at | -0.0254 | 0.9242 | |
| GSE45670 | ENPP7 | 339221 | 238245_at | 0.1425 | 0.2122 | |
| GSE53622 | ENPP7 | 339221 | 82701 | 0.1183 | 0.1397 | |
| GSE53624 | ENPP7 | 339221 | 82701 | 0.1158 | 0.1908 | |
| GSE63941 | ENPP7 | 339221 | 238245_at | -0.2525 | 0.1764 | |
| GSE77861 | ENPP7 | 339221 | 238245_at | 0.0048 | 0.9708 | |
| GSE97050 | ENPP7 | 339221 | A_33_P3383491 | 0.0360 | 0.8944 | |
| TCGA | ENPP7 | 339221 | RNAseq | 0.2237 | 0.9075 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ENPP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENPP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENPP7 | 339221 | 4 | 3 | 23 | |
| GSE20123 | ENPP7 | 339221 | 4 | 3 | 23 | |
| GSE43470 | ENPP7 | 339221 | 3 | 5 | 35 | |
| GSE46452 | ENPP7 | 339221 | 34 | 0 | 25 | |
| GSE47630 | ENPP7 | 339221 | 9 | 1 | 30 | |
| GSE54993 | ENPP7 | 339221 | 2 | 5 | 63 | |
| GSE54994 | ENPP7 | 339221 | 10 | 5 | 38 | |
| GSE60625 | ENPP7 | 339221 | 6 | 0 | 5 | |
| GSE74703 | ENPP7 | 339221 | 3 | 3 | 30 | |
| GSE74704 | ENPP7 | 339221 | 4 | 3 | 13 | |
| TCGA | ENPP7 | 339221 | 29 | 9 | 58 |
Total number of gains: 108; Total number of losses: 37; Total Number of normals: 343.
Somatic mutations of ENPP7:
Generating mutation plots.
Highly correlated genes for ENPP7:
Showing top 20/176 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENPP7 | INSC | 0.781234 | 3 | 0 | 3 |
| ENPP7 | DUSP9 | 0.776818 | 3 | 0 | 3 |
| ENPP7 | PRSS38 | 0.766762 | 3 | 0 | 3 |
| ENPP7 | NRIP3 | 0.760515 | 3 | 0 | 3 |
| ENPP7 | TNXB | 0.750999 | 3 | 0 | 3 |
| ENPP7 | OR2T1 | 0.750447 | 3 | 0 | 3 |
| ENPP7 | KIF26B | 0.734297 | 3 | 0 | 3 |
| ENPP7 | SERPINA10 | 0.72601 | 3 | 0 | 3 |
| ENPP7 | USP51 | 0.723561 | 3 | 0 | 3 |
| ENPP7 | OR2T27 | 0.722804 | 3 | 0 | 3 |
| ENPP7 | ZBTB46 | 0.719684 | 3 | 0 | 3 |
| ENPP7 | PROCA1 | 0.719226 | 3 | 0 | 3 |
| ENPP7 | YY2 | 0.717891 | 3 | 0 | 3 |
| ENPP7 | DCDC1 | 0.716893 | 3 | 0 | 3 |
| ENPP7 | TNFAIP8L1 | 0.713394 | 4 | 0 | 4 |
| ENPP7 | OR2B11 | 0.710592 | 3 | 0 | 3 |
| ENPP7 | RIMS3 | 0.709192 | 3 | 0 | 3 |
| ENPP7 | ABTB1 | 0.704191 | 4 | 0 | 4 |
| ENPP7 | GRXCR2 | 0.701276 | 3 | 0 | 3 |
| ENPP7 | CABP1 | 0.699884 | 3 | 0 | 3 |
For details and further investigation, click here
