| Full name: zinc finger and BTB domain containing 46 | Alias Symbol: FLJ13502|RINZF|BZEL | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 140685 | HGNC ID: HGNC:16094 | Ensembl Gene: ENSG00000130584 | OMIM ID: 614639 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB46:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB46 | 140685 | 227329_at | 0.5286 | 0.0953 | |
| GSE26886 | ZBTB46 | 140685 | 227329_at | 0.0894 | 0.8337 | |
| GSE45670 | ZBTB46 | 140685 | 227358_at | 0.0925 | 0.3644 | |
| GSE53622 | ZBTB46 | 140685 | 95807 | 0.3524 | 0.0000 | |
| GSE53624 | ZBTB46 | 140685 | 60781 | 0.5896 | 0.0000 | |
| GSE63941 | ZBTB46 | 140685 | 227329_at | -1.7139 | 0.0003 | |
| GSE77861 | ZBTB46 | 140685 | 227358_at | -0.2025 | 0.1466 | |
| GSE97050 | ZBTB46 | 140685 | A_33_P3266674 | 0.0247 | 0.9147 | |
| SRP007169 | ZBTB46 | 140685 | RNAseq | -0.5688 | 0.2675 | |
| SRP008496 | ZBTB46 | 140685 | RNAseq | 0.3024 | 0.4991 | |
| SRP064894 | ZBTB46 | 140685 | RNAseq | 0.4632 | 0.0236 | |
| SRP133303 | ZBTB46 | 140685 | RNAseq | -0.1430 | 0.5504 | |
| SRP159526 | ZBTB46 | 140685 | RNAseq | 0.3705 | 0.2934 | |
| SRP193095 | ZBTB46 | 140685 | RNAseq | 0.4737 | 0.0049 | |
| SRP219564 | ZBTB46 | 140685 | RNAseq | 0.0576 | 0.8666 | |
| TCGA | ZBTB46 | 140685 | RNAseq | -0.2387 | 0.0728 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZBTB46 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB46:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB46 | 140685 | 14 | 2 | 14 | |
| GSE20123 | ZBTB46 | 140685 | 14 | 2 | 14 | |
| GSE43470 | ZBTB46 | 140685 | 11 | 1 | 31 | |
| GSE46452 | ZBTB46 | 140685 | 35 | 0 | 24 | |
| GSE47630 | ZBTB46 | 140685 | 25 | 1 | 14 | |
| GSE54993 | ZBTB46 | 140685 | 0 | 17 | 53 | |
| GSE54994 | ZBTB46 | 140685 | 29 | 0 | 24 | |
| GSE60625 | ZBTB46 | 140685 | 0 | 0 | 11 | |
| GSE74703 | ZBTB46 | 140685 | 10 | 0 | 26 | |
| GSE74704 | ZBTB46 | 140685 | 11 | 0 | 9 | |
| TCGA | ZBTB46 | 140685 | 44 | 4 | 48 |
Total number of gains: 193; Total number of losses: 27; Total Number of normals: 268.
Somatic mutations of ZBTB46:
Generating mutation plots.
Highly correlated genes for ZBTB46:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB46 | PTAFR | 0.766493 | 3 | 0 | 3 |
| ZBTB46 | CABP1 | 0.760071 | 3 | 0 | 3 |
| ZBTB46 | SLC18A3 | 0.752053 | 3 | 0 | 3 |
| ZBTB46 | PNPLA7 | 0.75157 | 3 | 0 | 3 |
| ZBTB46 | FFAR1 | 0.748989 | 3 | 0 | 3 |
| ZBTB46 | RFT1 | 0.748779 | 3 | 0 | 3 |
| ZBTB46 | TTLL9 | 0.745826 | 3 | 0 | 3 |
| ZBTB46 | PAX6 | 0.740154 | 3 | 0 | 3 |
| ZBTB46 | BMP8B | 0.73981 | 3 | 0 | 3 |
| ZBTB46 | USP51 | 0.73482 | 3 | 0 | 3 |
| ZBTB46 | AQP8 | 0.726553 | 3 | 0 | 3 |
| ZBTB46 | AGRP | 0.72242 | 3 | 0 | 3 |
| ZBTB46 | ENPP7 | 0.719684 | 3 | 0 | 3 |
| ZBTB46 | GSDMD | 0.719077 | 3 | 0 | 3 |
| ZBTB46 | ZAN | 0.714139 | 3 | 0 | 3 |
| ZBTB46 | DFFB | 0.71352 | 4 | 0 | 3 |
| ZBTB46 | GPR25 | 0.701156 | 3 | 0 | 3 |
| ZBTB46 | VAV2 | 0.697246 | 4 | 0 | 3 |
| ZBTB46 | SLC22A31 | 0.693724 | 4 | 0 | 3 |
| ZBTB46 | RHBDD3 | 0.688875 | 4 | 0 | 3 |
For details and further investigation, click here
