| Full name: regulating synaptic membrane exocytosis 3 | Alias Symbol: RIM3|NIM3 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 9783 | HGNC ID: HGNC:21292 | Ensembl Gene: ENSG00000117016 | OMIM ID: 611600 |
| Drug and gene relationship at DGIdb | |||
Expression of RIMS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RIMS3 | 9783 | 204730_at | 0.5085 | 0.4640 | |
| GSE20347 | RIMS3 | 9783 | 210991_s_at | 0.0167 | 0.8819 | |
| GSE23400 | RIMS3 | 9783 | 210991_s_at | -0.0077 | 0.9008 | |
| GSE26886 | RIMS3 | 9783 | 204730_at | 0.2490 | 0.6134 | |
| GSE29001 | RIMS3 | 9783 | 210991_s_at | 0.3045 | 0.2007 | |
| GSE38129 | RIMS3 | 9783 | 204730_at | -0.0547 | 0.8658 | |
| GSE45670 | RIMS3 | 9783 | 204730_at | 0.9209 | 0.0093 | |
| GSE53622 | RIMS3 | 9783 | 91981 | -0.4812 | 0.0002 | |
| GSE53624 | RIMS3 | 9783 | 91981 | -0.2095 | 0.0974 | |
| GSE63941 | RIMS3 | 9783 | 204730_at | 1.1370 | 0.1691 | |
| GSE77861 | RIMS3 | 9783 | 210991_s_at | 0.0970 | 0.6336 | |
| GSE97050 | RIMS3 | 9783 | A_23_P319583 | -0.3406 | 0.4612 | |
| SRP007169 | RIMS3 | 9783 | RNAseq | -1.7367 | 0.0065 | |
| SRP064894 | RIMS3 | 9783 | RNAseq | 1.0774 | 0.0001 | |
| SRP133303 | RIMS3 | 9783 | RNAseq | -0.1417 | 0.6786 | |
| SRP159526 | RIMS3 | 9783 | RNAseq | -0.1196 | 0.7866 | |
| SRP193095 | RIMS3 | 9783 | RNAseq | 1.0437 | 0.0000 | |
| SRP219564 | RIMS3 | 9783 | RNAseq | 0.7621 | 0.2505 | |
| TCGA | RIMS3 | 9783 | RNAseq | -0.7130 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by RIMS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RIMS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RIMS3 | 9783 | 3 | 4 | 23 | |
| GSE20123 | RIMS3 | 9783 | 2 | 3 | 25 | |
| GSE43470 | RIMS3 | 9783 | 7 | 2 | 34 | |
| GSE46452 | RIMS3 | 9783 | 4 | 1 | 54 | |
| GSE47630 | RIMS3 | 9783 | 9 | 2 | 29 | |
| GSE54993 | RIMS3 | 9783 | 0 | 1 | 69 | |
| GSE54994 | RIMS3 | 9783 | 13 | 2 | 38 | |
| GSE60625 | RIMS3 | 9783 | 0 | 0 | 11 | |
| GSE74703 | RIMS3 | 9783 | 6 | 1 | 29 | |
| GSE74704 | RIMS3 | 9783 | 1 | 0 | 19 | |
| TCGA | RIMS3 | 9783 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 32; Total Number of normals: 395.
Somatic mutations of RIMS3:
Generating mutation plots.
Highly correlated genes for RIMS3:
Showing top 20/145 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RIMS3 | ZNF428 | 0.719034 | 3 | 0 | 3 |
| RIMS3 | ENPP7 | 0.709192 | 3 | 0 | 3 |
| RIMS3 | LUZP1 | 0.685315 | 3 | 0 | 3 |
| RIMS3 | KLHL26 | 0.680217 | 3 | 0 | 3 |
| RIMS3 | C19orf25 | 0.674499 | 3 | 0 | 3 |
| RIMS3 | NAT14 | 0.669597 | 3 | 0 | 3 |
| RIMS3 | IFT27 | 0.665745 | 4 | 0 | 4 |
| RIMS3 | BAHCC1 | 0.6628 | 5 | 0 | 4 |
| RIMS3 | TRIM36 | 0.656853 | 4 | 0 | 3 |
| RIMS3 | LINC01128 | 0.65297 | 3 | 0 | 3 |
| RIMS3 | FBXL2 | 0.646632 | 5 | 0 | 4 |
| RIMS3 | SFXN3 | 0.643527 | 4 | 0 | 4 |
| RIMS3 | GFRA4 | 0.639691 | 3 | 0 | 3 |
| RIMS3 | PHLPP2 | 0.638507 | 5 | 0 | 4 |
| RIMS3 | SIM1 | 0.628158 | 3 | 0 | 3 |
| RIMS3 | IER5L | 0.626797 | 4 | 0 | 4 |
| RIMS3 | CC2D1B | 0.62344 | 3 | 0 | 3 |
| RIMS3 | ACTL8 | 0.621453 | 3 | 0 | 3 |
| RIMS3 | PCSK1N | 0.621414 | 5 | 0 | 3 |
| RIMS3 | GEMIN2 | 0.619467 | 4 | 0 | 4 |
For details and further investigation, click here
