| Full name: dual specificity phosphatase 9 | Alias Symbol: MKP-4|MKP4 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 1852 | HGNC ID: HGNC:3076 | Ensembl Gene: ENSG00000130829 | OMIM ID: 300134 |
| Drug and gene relationship at DGIdb | |||
DUSP9 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway | |
| hsa04550 | Signaling pathways regulating pluripotency of stem cells |
Expression of DUSP9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DUSP9 | 1852 | 205777_at | 0.9205 | 0.0302 | |
| GSE20347 | DUSP9 | 1852 | 205777_at | 0.7770 | 0.0001 | |
| GSE23400 | DUSP9 | 1852 | 205777_at | 0.2224 | 0.0020 | |
| GSE26886 | DUSP9 | 1852 | 205777_at | 1.1682 | 0.0000 | |
| GSE29001 | DUSP9 | 1852 | 205777_at | 0.9039 | 0.0020 | |
| GSE38129 | DUSP9 | 1852 | 205777_at | 0.7601 | 0.0000 | |
| GSE45670 | DUSP9 | 1852 | 205777_at | 0.5374 | 0.0065 | |
| GSE53622 | DUSP9 | 1852 | 79055 | 0.1341 | 0.4446 | |
| GSE53624 | DUSP9 | 1852 | 79055 | 0.3136 | 0.0054 | |
| GSE63941 | DUSP9 | 1852 | 205777_at | 1.0350 | 0.1979 | |
| GSE77861 | DUSP9 | 1852 | 205777_at | 0.2270 | 0.3176 | |
| GSE97050 | DUSP9 | 1852 | A_24_P417189 | 0.2498 | 0.2660 | |
| SRP007169 | DUSP9 | 1852 | RNAseq | 3.3263 | 0.0002 | |
| SRP133303 | DUSP9 | 1852 | RNAseq | 4.4240 | 0.0000 | |
| SRP159526 | DUSP9 | 1852 | RNAseq | 3.6970 | 0.0000 | |
| SRP219564 | DUSP9 | 1852 | RNAseq | 4.9023 | 0.0000 | |
| TCGA | DUSP9 | 1852 | RNAseq | 3.0147 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by DUSP9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DUSP9:
No record found for this gene.
Somatic mutations of DUSP9:
Generating mutation plots.
Highly correlated genes for DUSP9:
Showing top 20/642 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DUSP9 | TRIM17 | 0.860093 | 3 | 0 | 3 |
| DUSP9 | NPBWR1 | 0.782201 | 3 | 0 | 3 |
| DUSP9 | ZNF524 | 0.778861 | 3 | 0 | 3 |
| DUSP9 | CMSS1 | 0.778062 | 3 | 0 | 3 |
| DUSP9 | LRR1 | 0.777932 | 3 | 0 | 3 |
| DUSP9 | ENPP7 | 0.776818 | 3 | 0 | 3 |
| DUSP9 | BAHCC1 | 0.775119 | 3 | 0 | 3 |
| DUSP9 | KNSTRN | 0.769919 | 3 | 0 | 3 |
| DUSP9 | C20orf141 | 0.769757 | 3 | 0 | 3 |
| DUSP9 | NPW | 0.764108 | 5 | 0 | 5 |
| DUSP9 | ORM1 | 0.756009 | 3 | 0 | 3 |
| DUSP9 | C19orf81 | 0.746607 | 3 | 0 | 3 |
| DUSP9 | TUBA3C | 0.746566 | 3 | 0 | 3 |
| DUSP9 | HTR6 | 0.732256 | 4 | 0 | 4 |
| DUSP9 | NTMT1 | 0.731588 | 4 | 0 | 4 |
| DUSP9 | SHISA4 | 0.728727 | 3 | 0 | 3 |
| DUSP9 | SPATA2L | 0.728703 | 5 | 0 | 4 |
| DUSP9 | SHANK1 | 0.728623 | 3 | 0 | 3 |
| DUSP9 | BCL2L12 | 0.727046 | 5 | 0 | 5 |
| DUSP9 | STK11 | 0.725906 | 3 | 0 | 3 |
For details and further investigation, click here
