| Full name: DEAD-box helicase 42 | Alias Symbol: RNAHP|RHELP|SF3b125|SF3B8 | ||
| Type: protein-coding gene | Cytoband: 17q23.3 | ||
| Entrez ID: 11325 | HGNC ID: HGNC:18676 | Ensembl Gene: ENSG00000198231 | OMIM ID: 613369 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DDX42:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX42 | 11325 | 201788_at | -0.1617 | 0.6293 | |
| GSE20347 | DDX42 | 11325 | 201788_at | -0.0764 | 0.4449 | |
| GSE23400 | DDX42 | 11325 | 201788_at | 0.0912 | 0.0873 | |
| GSE26886 | DDX42 | 11325 | 201788_at | 0.4191 | 0.0317 | |
| GSE29001 | DDX42 | 11325 | 201788_at | 0.0574 | 0.8069 | |
| GSE38129 | DDX42 | 11325 | 201788_at | -0.0940 | 0.2966 | |
| GSE45670 | DDX42 | 11325 | 201788_at | -0.1193 | 0.2890 | |
| GSE63941 | DDX42 | 11325 | 201788_at | -0.1190 | 0.6405 | |
| GSE77861 | DDX42 | 11325 | 201788_at | 0.5138 | 0.0566 | |
| GSE97050 | DDX42 | 11325 | A_23_P152651 | -0.2466 | 0.2994 | |
| SRP007169 | DDX42 | 11325 | RNAseq | 0.0657 | 0.8505 | |
| SRP008496 | DDX42 | 11325 | RNAseq | 0.1008 | 0.6597 | |
| SRP064894 | DDX42 | 11325 | RNAseq | 0.0570 | 0.6587 | |
| SRP133303 | DDX42 | 11325 | RNAseq | 0.1225 | 0.4355 | |
| SRP159526 | DDX42 | 11325 | RNAseq | 0.0827 | 0.6451 | |
| SRP193095 | DDX42 | 11325 | RNAseq | -0.0732 | 0.3263 | |
| SRP219564 | DDX42 | 11325 | RNAseq | 0.2057 | 0.4594 | |
| TCGA | DDX42 | 11325 | RNAseq | -0.0781 | 0.0604 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDX42 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of DDX42:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX42 | 11325 | 3 | 1 | 26 | |
| GSE20123 | DDX42 | 11325 | 3 | 1 | 26 | |
| GSE43470 | DDX42 | 11325 | 4 | 0 | 39 | |
| GSE46452 | DDX42 | 11325 | 31 | 0 | 28 | |
| GSE47630 | DDX42 | 11325 | 7 | 1 | 32 | |
| GSE54993 | DDX42 | 11325 | 2 | 5 | 63 | |
| GSE54994 | DDX42 | 11325 | 9 | 4 | 40 | |
| GSE60625 | DDX42 | 11325 | 4 | 0 | 7 | |
| GSE74703 | DDX42 | 11325 | 4 | 0 | 32 | |
| GSE74704 | DDX42 | 11325 | 3 | 1 | 16 | |
| TCGA | DDX42 | 11325 | 31 | 9 | 56 |
Total number of gains: 101; Total number of losses: 22; Total Number of normals: 365.
Somatic mutations of DDX42:
Generating mutation plots.
Highly correlated genes for DDX42:
Showing top 20/537 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX42 | DMPK | 0.799398 | 3 | 0 | 3 |
| DDX42 | ZCRB1 | 0.793626 | 3 | 0 | 3 |
| DDX42 | MECP2 | 0.77282 | 3 | 0 | 3 |
| DDX42 | CBX7 | 0.772015 | 3 | 0 | 3 |
| DDX42 | CAND2 | 0.771045 | 4 | 0 | 3 |
| DDX42 | MYOT | 0.769996 | 3 | 0 | 3 |
| DDX42 | GADD45G | 0.763283 | 3 | 0 | 3 |
| DDX42 | PYGM | 0.754645 | 3 | 0 | 3 |
| DDX42 | KANSL1 | 0.750884 | 3 | 0 | 3 |
| DDX42 | CHRDL1 | 0.748408 | 3 | 0 | 3 |
| DDX42 | TMOD1 | 0.746997 | 3 | 0 | 3 |
| DDX42 | SESTD1 | 0.746919 | 4 | 0 | 4 |
| DDX42 | ZBTB4 | 0.735279 | 4 | 0 | 4 |
| DDX42 | ZER1 | 0.734765 | 3 | 0 | 3 |
| DDX42 | ZBTB16 | 0.733017 | 3 | 0 | 3 |
| DDX42 | TNS1 | 0.731539 | 3 | 0 | 3 |
| DDX42 | PPP1R9A | 0.731255 | 3 | 0 | 3 |
| DDX42 | PCDH9 | 0.7311 | 3 | 0 | 3 |
| DDX42 | SYNC | 0.730755 | 3 | 0 | 3 |
| DDX42 | PBX1 | 0.730015 | 3 | 0 | 3 |
For details and further investigation, click here
