| Full name: spermidine/spermine N1-acetyltransferase family member 2 | Alias Symbol: SSAT2 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 112483 | HGNC ID: HGNC:23160 | Ensembl Gene: ENSG00000141504 | OMIM ID: 611463 |
| Drug and gene relationship at DGIdb | |||
Expression of SAT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAT2 | 112483 | 225272_at | -0.3353 | 0.4175 | |
| GSE26886 | SAT2 | 112483 | 225272_at | 0.5339 | 0.0272 | |
| GSE45670 | SAT2 | 112483 | 225272_at | -0.1818 | 0.3108 | |
| GSE53622 | SAT2 | 112483 | 83095 | -0.1589 | 0.0047 | |
| GSE53624 | SAT2 | 112483 | 38924 | -0.1815 | 0.0037 | |
| GSE63941 | SAT2 | 112483 | 225272_at | -0.7557 | 0.1807 | |
| GSE77861 | SAT2 | 112483 | 225272_at | 0.1285 | 0.6441 | |
| GSE97050 | SAT2 | 112483 | A_23_P15402 | -0.2235 | 0.3803 | |
| SRP007169 | SAT2 | 112483 | RNAseq | 0.2087 | 0.7325 | |
| SRP008496 | SAT2 | 112483 | RNAseq | 0.7125 | 0.0714 | |
| SRP064894 | SAT2 | 112483 | RNAseq | -0.1319 | 0.6742 | |
| SRP133303 | SAT2 | 112483 | RNAseq | -0.5268 | 0.0002 | |
| SRP159526 | SAT2 | 112483 | RNAseq | 0.1870 | 0.4185 | |
| SRP193095 | SAT2 | 112483 | RNAseq | -0.2175 | 0.0985 | |
| SRP219564 | SAT2 | 112483 | RNAseq | -0.1202 | 0.7661 | |
| TCGA | SAT2 | 112483 | RNAseq | -0.2482 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SAT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAT2 | 112483 | 4 | 2 | 24 | |
| GSE20123 | SAT2 | 112483 | 4 | 3 | 23 | |
| GSE43470 | SAT2 | 112483 | 1 | 6 | 36 | |
| GSE46452 | SAT2 | 112483 | 34 | 1 | 24 | |
| GSE47630 | SAT2 | 112483 | 7 | 1 | 32 | |
| GSE54993 | SAT2 | 112483 | 4 | 3 | 63 | |
| GSE54994 | SAT2 | 112483 | 5 | 8 | 40 | |
| GSE60625 | SAT2 | 112483 | 4 | 0 | 7 | |
| GSE74703 | SAT2 | 112483 | 1 | 3 | 32 | |
| GSE74704 | SAT2 | 112483 | 2 | 1 | 17 | |
| TCGA | SAT2 | 112483 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of SAT2:
Generating mutation plots.
Highly correlated genes for SAT2:
Showing top 20/384 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAT2 | USPL1 | 0.805885 | 3 | 0 | 3 |
| SAT2 | EPC2 | 0.791808 | 3 | 0 | 3 |
| SAT2 | FZD7 | 0.78885 | 4 | 0 | 4 |
| SAT2 | SESN1 | 0.757842 | 3 | 0 | 3 |
| SAT2 | TUBGCP3 | 0.745616 | 3 | 0 | 3 |
| SAT2 | RNF115 | 0.739838 | 3 | 0 | 3 |
| SAT2 | NAP1L1 | 0.738655 | 3 | 0 | 3 |
| SAT2 | MTR | 0.736352 | 3 | 0 | 3 |
| SAT2 | DHRS12 | 0.73547 | 3 | 0 | 3 |
| SAT2 | ZMAT1 | 0.733966 | 4 | 0 | 3 |
| SAT2 | DPY19L2 | 0.725255 | 3 | 0 | 3 |
| SAT2 | PIP5K1C | 0.722049 | 3 | 0 | 3 |
| SAT2 | VAMP2 | 0.715012 | 3 | 0 | 3 |
| SAT2 | PACSIN2 | 0.713461 | 3 | 0 | 3 |
| SAT2 | TIAM2 | 0.713385 | 3 | 0 | 3 |
| SAT2 | CEP44 | 0.705177 | 3 | 0 | 3 |
| SAT2 | ZMAT4 | 0.705095 | 3 | 0 | 3 |
| SAT2 | RP9 | 0.704484 | 3 | 0 | 3 |
| SAT2 | BOC | 0.700427 | 3 | 0 | 3 |
| SAT2 | CD63 | 0.700051 | 3 | 0 | 3 |
For details and further investigation, click here
