| Full name: AE binding protein 2 | Alias Symbol: MGC17922 | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 121536 | HGNC ID: HGNC:24051 | Ensembl Gene: ENSG00000139154 | OMIM ID: 617934 |
| Drug and gene relationship at DGIdb | |||
Expression of AEBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AEBP2 | 121536 | 225889_at | 0.3591 | 0.3514 | |
| GSE26886 | AEBP2 | 121536 | 225889_at | 0.1978 | 0.5850 | |
| GSE45670 | AEBP2 | 121536 | 225889_at | 0.1375 | 0.4565 | |
| GSE53622 | AEBP2 | 121536 | 71893 | 0.1211 | 0.1183 | |
| GSE53624 | AEBP2 | 121536 | 71893 | 0.0435 | 0.5299 | |
| GSE63941 | AEBP2 | 121536 | 225889_at | 0.3618 | 0.4681 | |
| GSE77861 | AEBP2 | 121536 | 225889_at | 0.4748 | 0.1949 | |
| GSE97050 | AEBP2 | 121536 | A_24_P18621 | -0.1474 | 0.5568 | |
| SRP007169 | AEBP2 | 121536 | RNAseq | 0.8565 | 0.0648 | |
| SRP008496 | AEBP2 | 121536 | RNAseq | 1.1313 | 0.0001 | |
| SRP064894 | AEBP2 | 121536 | RNAseq | -0.2063 | 0.3575 | |
| SRP133303 | AEBP2 | 121536 | RNAseq | 0.4816 | 0.0323 | |
| SRP159526 | AEBP2 | 121536 | RNAseq | -0.0463 | 0.8206 | |
| SRP193095 | AEBP2 | 121536 | RNAseq | 0.0371 | 0.7567 | |
| SRP219564 | AEBP2 | 121536 | RNAseq | -0.1731 | 0.5690 | |
| TCGA | AEBP2 | 121536 | RNAseq | 0.2207 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by AEBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AEBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AEBP2 | 121536 | 9 | 2 | 19 | |
| GSE20123 | AEBP2 | 121536 | 9 | 2 | 19 | |
| GSE43470 | AEBP2 | 121536 | 9 | 4 | 30 | |
| GSE46452 | AEBP2 | 121536 | 10 | 1 | 48 | |
| GSE47630 | AEBP2 | 121536 | 14 | 1 | 25 | |
| GSE54993 | AEBP2 | 121536 | 1 | 9 | 60 | |
| GSE54994 | AEBP2 | 121536 | 11 | 2 | 40 | |
| GSE60625 | AEBP2 | 121536 | 0 | 1 | 10 | |
| GSE74703 | AEBP2 | 121536 | 9 | 3 | 24 | |
| GSE74704 | AEBP2 | 121536 | 6 | 1 | 13 | |
| TCGA | AEBP2 | 121536 | 42 | 7 | 47 |
Total number of gains: 120; Total number of losses: 33; Total Number of normals: 335.
Somatic mutations of AEBP2:
Generating mutation plots.
Highly correlated genes for AEBP2:
Showing top 20/313 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AEBP2 | AIFM1 | 0.821814 | 3 | 0 | 3 |
| AEBP2 | NIPA2 | 0.817342 | 3 | 0 | 3 |
| AEBP2 | PPFIBP1 | 0.764025 | 3 | 0 | 3 |
| AEBP2 | DHX57 | 0.754956 | 3 | 0 | 3 |
| AEBP2 | SMC2 | 0.751787 | 3 | 0 | 3 |
| AEBP2 | LBR | 0.749688 | 3 | 0 | 3 |
| AEBP2 | ZNF200 | 0.746873 | 3 | 0 | 3 |
| AEBP2 | NMI | 0.738313 | 3 | 0 | 3 |
| AEBP2 | PPP1R10 | 0.735814 | 3 | 0 | 3 |
| AEBP2 | TAS2R19 | 0.729985 | 4 | 0 | 4 |
| AEBP2 | PTGFRN | 0.724047 | 3 | 0 | 3 |
| AEBP2 | NUP54 | 0.720915 | 3 | 0 | 3 |
| AEBP2 | SIVA1 | 0.72071 | 3 | 0 | 3 |
| AEBP2 | CREBL2 | 0.720508 | 4 | 0 | 3 |
| AEBP2 | EPC2 | 0.719037 | 3 | 0 | 3 |
| AEBP2 | RUNDC1 | 0.718413 | 3 | 0 | 3 |
| AEBP2 | IRF2BPL | 0.715655 | 4 | 0 | 4 |
| AEBP2 | SP3 | 0.712832 | 4 | 0 | 4 |
| AEBP2 | C1orf112 | 0.711404 | 3 | 0 | 3 |
| AEBP2 | PARN | 0.705141 | 3 | 0 | 3 |
For details and further investigation, click here
