| Full name: epiplakin 1 | Alias Symbol: EPIPL1 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 83481 | HGNC ID: HGNC:15577 | Ensembl Gene: ENSG00000261150 | OMIM ID: 607553 |
Expression of EPPK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPPK1 | 83481 | 232164_s_at | 1.8610 | 0.0661 | |
| GSE20347 | EPPK1 | 83481 | 208156_x_at | 0.6089 | 0.0001 | |
| GSE23400 | EPPK1 | 83481 | 208156_x_at | 0.2666 | 0.0017 | |
| GSE26886 | EPPK1 | 83481 | 232165_at | 2.0812 | 0.0000 | |
| GSE29001 | EPPK1 | 83481 | 208156_x_at | 0.8057 | 0.0543 | |
| GSE38129 | EPPK1 | 83481 | 208156_x_at | 0.4982 | 0.0043 | |
| GSE45670 | EPPK1 | 83481 | 232165_at | 2.5028 | 0.0000 | |
| GSE63941 | EPPK1 | 83481 | 232164_s_at | 5.5182 | 0.0001 | |
| GSE77861 | EPPK1 | 83481 | 232164_s_at | 2.4229 | 0.0019 | |
| GSE97050 | EPPK1 | 83481 | A_24_P357169 | 0.2689 | 0.6352 | |
| SRP007169 | EPPK1 | 83481 | RNAseq | 2.7241 | 0.0000 | |
| SRP008496 | EPPK1 | 83481 | RNAseq | 1.7843 | 0.0000 | |
| SRP064894 | EPPK1 | 83481 | RNAseq | 1.3818 | 0.0009 | |
| SRP133303 | EPPK1 | 83481 | RNAseq | 1.7185 | 0.0000 | |
| SRP159526 | EPPK1 | 83481 | RNAseq | 1.5270 | 0.0009 | |
| SRP193095 | EPPK1 | 83481 | RNAseq | 2.1199 | 0.0000 | |
| SRP219564 | EPPK1 | 83481 | RNAseq | 2.3002 | 0.0153 | |
| TCGA | EPPK1 | 83481 | RNAseq | 0.2486 | 0.0601 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by EPPK1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of EPPK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPPK1 | 83481 | 17 | 1 | 12 | |
| GSE20123 | EPPK1 | 83481 | 17 | 1 | 12 | |
| GSE43470 | EPPK1 | 83481 | 16 | 2 | 25 | |
| GSE46452 | EPPK1 | 83481 | 27 | 0 | 32 | |
| GSE47630 | EPPK1 | 83481 | 23 | 1 | 16 | |
| GSE54993 | EPPK1 | 83481 | 0 | 25 | 45 | |
| GSE54994 | EPPK1 | 83481 | 39 | 1 | 13 | |
| GSE60625 | EPPK1 | 83481 | 3 | 4 | 4 | |
| GSE74703 | EPPK1 | 83481 | 14 | 1 | 21 | |
| GSE74704 | EPPK1 | 83481 | 10 | 0 | 10 | |
| TCGA | EPPK1 | 83481 | 64 | 2 | 30 |
Total number of gains: 230; Total number of losses: 38; Total Number of normals: 220.
Somatic mutations of EPPK1:
Generating mutation plots.
Highly correlated genes for EPPK1:
Showing top 20/1634 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPPK1 | PPP1R14C | 0.829641 | 3 | 0 | 3 |
| EPPK1 | ISCA1 | 0.797265 | 3 | 0 | 3 |
| EPPK1 | WDR66 | 0.791922 | 5 | 0 | 5 |
| EPPK1 | EMILIN2 | 0.778119 | 4 | 0 | 4 |
| EPPK1 | CPNE8 | 0.766907 | 5 | 0 | 5 |
| EPPK1 | CMSS1 | 0.766538 | 5 | 0 | 5 |
| EPPK1 | RILPL2 | 0.761438 | 3 | 0 | 3 |
| EPPK1 | CCM2 | 0.761009 | 5 | 0 | 4 |
| EPPK1 | PRTFDC1 | 0.754767 | 4 | 0 | 4 |
| EPPK1 | GOLIM4 | 0.753909 | 6 | 0 | 5 |
| EPPK1 | ZNF275 | 0.752361 | 3 | 0 | 3 |
| EPPK1 | SLC41A1 | 0.750673 | 5 | 0 | 5 |
| EPPK1 | TRMT2B | 0.749729 | 3 | 0 | 3 |
| EPPK1 | SLC6A6 | 0.749246 | 4 | 0 | 4 |
| EPPK1 | TP53I13 | 0.748341 | 4 | 0 | 4 |
| EPPK1 | PIK3R3 | 0.745786 | 3 | 0 | 3 |
| EPPK1 | RILPL1 | 0.740077 | 3 | 0 | 3 |
| EPPK1 | F2RL1 | 0.739134 | 4 | 0 | 4 |
| EPPK1 | WDR4 | 0.739107 | 4 | 0 | 4 |
| EPPK1 | ZNF317 | 0.738635 | 3 | 0 | 3 |
For details and further investigation, click here
