| Full name: solute carrier family 6 member 6 | Alias Symbol: TAUT | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 6533 | HGNC ID: HGNC:11052 | Ensembl Gene: ENSG00000131389 | OMIM ID: 186854 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC6A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A6 | 6533 | 228754_at | 0.3158 | 0.7725 | |
| GSE20347 | SLC6A6 | 6533 | 205920_at | 0.2175 | 0.0215 | |
| GSE23400 | SLC6A6 | 6533 | 205920_at | 0.0156 | 0.7372 | |
| GSE26886 | SLC6A6 | 6533 | 228754_at | 1.2093 | 0.0000 | |
| GSE29001 | SLC6A6 | 6533 | 205920_at | -0.0545 | 0.7281 | |
| GSE38129 | SLC6A6 | 6533 | 205920_at | 0.1737 | 0.0658 | |
| GSE45670 | SLC6A6 | 6533 | 228754_at | 0.0954 | 0.8082 | |
| GSE53622 | SLC6A6 | 6533 | 26370 | 0.6880 | 0.0000 | |
| GSE53624 | SLC6A6 | 6533 | 26370 | 0.7611 | 0.0000 | |
| GSE63941 | SLC6A6 | 6533 | 228754_at | -1.1900 | 0.2376 | |
| GSE77861 | SLC6A6 | 6533 | 228754_at | 1.0516 | 0.0070 | |
| GSE97050 | SLC6A6 | 6533 | A_24_P359191 | 0.8282 | 0.0976 | |
| SRP007169 | SLC6A6 | 6533 | RNAseq | 1.4434 | 0.0068 | |
| SRP008496 | SLC6A6 | 6533 | RNAseq | 2.3318 | 0.0000 | |
| SRP064894 | SLC6A6 | 6533 | RNAseq | 0.2848 | 0.3686 | |
| SRP133303 | SLC6A6 | 6533 | RNAseq | 0.6624 | 0.0025 | |
| SRP159526 | SLC6A6 | 6533 | RNAseq | 0.5213 | 0.2767 | |
| SRP193095 | SLC6A6 | 6533 | RNAseq | 0.5697 | 0.0009 | |
| SRP219564 | SLC6A6 | 6533 | RNAseq | 0.4909 | 0.3044 | |
| TCGA | SLC6A6 | 6533 | RNAseq | 0.0431 | 0.6075 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SLC6A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A6 | 6533 | 1 | 19 | 10 | |
| GSE20123 | SLC6A6 | 6533 | 1 | 19 | 10 | |
| GSE43470 | SLC6A6 | 6533 | 0 | 21 | 22 | |
| GSE46452 | SLC6A6 | 6533 | 2 | 17 | 40 | |
| GSE47630 | SLC6A6 | 6533 | 2 | 23 | 15 | |
| GSE54993 | SLC6A6 | 6533 | 6 | 1 | 63 | |
| GSE54994 | SLC6A6 | 6533 | 1 | 32 | 20 | |
| GSE60625 | SLC6A6 | 6533 | 5 | 0 | 6 | |
| GSE74703 | SLC6A6 | 6533 | 0 | 17 | 19 | |
| GSE74704 | SLC6A6 | 6533 | 1 | 12 | 7 | |
| TCGA | SLC6A6 | 6533 | 2 | 68 | 26 |
Total number of gains: 21; Total number of losses: 229; Total Number of normals: 238.
Somatic mutations of SLC6A6:
Generating mutation plots.
Highly correlated genes for SLC6A6:
Showing top 20/985 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A6 | SLC38A10 | 0.843783 | 3 | 0 | 3 |
| SLC6A6 | CASC4 | 0.797823 | 3 | 0 | 3 |
| SLC6A6 | ADAR | 0.790331 | 4 | 0 | 4 |
| SLC6A6 | KRTCAP2 | 0.786385 | 3 | 0 | 3 |
| SLC6A6 | MEF2A | 0.781758 | 3 | 0 | 3 |
| SLC6A6 | CPSF3 | 0.773148 | 3 | 0 | 3 |
| SLC6A6 | ALKBH6 | 0.763582 | 3 | 0 | 3 |
| SLC6A6 | DNMT1 | 0.76273 | 5 | 0 | 5 |
| SLC6A6 | RGS1 | 0.7624 | 3 | 0 | 3 |
| SLC6A6 | CEP120 | 0.759397 | 3 | 0 | 3 |
| SLC6A6 | CDCA2 | 0.758322 | 3 | 0 | 3 |
| SLC6A6 | SRPK2 | 0.753666 | 3 | 0 | 3 |
| SLC6A6 | EPPK1 | 0.749246 | 4 | 0 | 4 |
| SLC6A6 | BUB1 | 0.748467 | 4 | 0 | 4 |
| SLC6A6 | LRCH3 | 0.746633 | 3 | 0 | 3 |
| SLC6A6 | ADCY3 | 0.744147 | 4 | 0 | 3 |
| SLC6A6 | SUPT7L | 0.741144 | 3 | 0 | 3 |
| SLC6A6 | STK17A | 0.737998 | 3 | 0 | 3 |
| SLC6A6 | ARHGEF10 | 0.735215 | 3 | 0 | 3 |
| SLC6A6 | PREX1 | 0.73443 | 3 | 0 | 3 |
For details and further investigation, click here
