| Full name: WD repeat domain 66 | Alias Symbol: MGC33630|CaM-IP4 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 144406 | HGNC ID: HGNC:28506 | Ensembl Gene: ENSG00000158023 | OMIM ID: 618146 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR66:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR66 | 144406 | 230193_at | 3.1256 | 0.0179 | |
| GSE26886 | WDR66 | 144406 | 230193_at | 5.3548 | 0.0000 | |
| GSE45670 | WDR66 | 144406 | 230193_at | 3.8691 | 0.0000 | |
| GSE53622 | WDR66 | 144406 | 8451 | 3.5324 | 0.0000 | |
| GSE53624 | WDR66 | 144406 | 8451 | 3.7114 | 0.0000 | |
| GSE63941 | WDR66 | 144406 | 230193_at | 3.7181 | 0.0115 | |
| GSE77861 | WDR66 | 144406 | 230193_at | 2.6737 | 0.0019 | |
| GSE97050 | WDR66 | 144406 | A_23_P363275 | 1.6552 | 0.1344 | |
| SRP007169 | WDR66 | 144406 | RNAseq | 4.2754 | 0.0000 | |
| SRP008496 | WDR66 | 144406 | RNAseq | 4.0584 | 0.0000 | |
| SRP064894 | WDR66 | 144406 | RNAseq | 3.5889 | 0.0000 | |
| SRP133303 | WDR66 | 144406 | RNAseq | 1.9031 | 0.0000 | |
| SRP159526 | WDR66 | 144406 | RNAseq | 4.5615 | 0.0000 | |
| SRP193095 | WDR66 | 144406 | RNAseq | 2.8039 | 0.0000 | |
| SRP219564 | WDR66 | 144406 | RNAseq | 2.6333 | 0.0000 | |
| TCGA | WDR66 | 144406 | RNAseq | 2.0539 | 0.0000 |
Upregulated datasets: 15; Downregulated datasets: 0.
Survival by WDR66 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR66:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR66 | 144406 | 5 | 4 | 21 | |
| GSE20123 | WDR66 | 144406 | 5 | 4 | 21 | |
| GSE43470 | WDR66 | 144406 | 2 | 2 | 39 | |
| GSE46452 | WDR66 | 144406 | 9 | 1 | 49 | |
| GSE47630 | WDR66 | 144406 | 9 | 3 | 28 | |
| GSE54993 | WDR66 | 144406 | 0 | 5 | 65 | |
| GSE54994 | WDR66 | 144406 | 6 | 7 | 40 | |
| GSE60625 | WDR66 | 144406 | 0 | 0 | 11 | |
| GSE74703 | WDR66 | 144406 | 2 | 1 | 33 | |
| GSE74704 | WDR66 | 144406 | 4 | 2 | 14 | |
| TCGA | WDR66 | 144406 | 21 | 10 | 65 |
Total number of gains: 63; Total number of losses: 39; Total Number of normals: 386.
Somatic mutations of WDR66:
Generating mutation plots.
Highly correlated genes for WDR66:
Showing top 20/1689 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR66 | MMP1 | 0.842654 | 7 | 0 | 7 |
| WDR66 | MYO10 | 0.805058 | 4 | 0 | 4 |
| WDR66 | COLGALT1 | 0.80118 | 6 | 0 | 6 |
| WDR66 | MFAP2 | 0.79792 | 7 | 0 | 7 |
| WDR66 | LAMC2 | 0.796674 | 8 | 0 | 7 |
| WDR66 | EPPK1 | 0.791922 | 5 | 0 | 5 |
| WDR66 | PLAU | 0.791873 | 7 | 0 | 7 |
| WDR66 | CTHRC1 | 0.789505 | 7 | 0 | 7 |
| WDR66 | SEMA4C | 0.784032 | 3 | 0 | 3 |
| WDR66 | IGF2BP2 | 0.782166 | 7 | 0 | 7 |
| WDR66 | SNAI2 | 0.77981 | 4 | 0 | 4 |
| WDR66 | CKS1B | 0.778436 | 8 | 0 | 8 |
| WDR66 | XPR1 | 0.778249 | 7 | 0 | 7 |
| WDR66 | MTERF3 | 0.777446 | 4 | 0 | 4 |
| WDR66 | FSCN1 | 0.776055 | 8 | 0 | 8 |
| WDR66 | ZNF593 | 0.774149 | 4 | 0 | 4 |
| WDR66 | KIAA0930 | 0.773617 | 7 | 0 | 7 |
| WDR66 | MARK1 | 0.773571 | 5 | 0 | 5 |
| WDR66 | TMEM184B | 0.773254 | 7 | 0 | 7 |
| WDR66 | LRRC8D | 0.773206 | 7 | 0 | 7 |
For details and further investigation, click here
