| Full name: copine 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 144402 | HGNC ID: HGNC:23498 | Ensembl Gene: ENSG00000139117 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CPNE8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPNE8 | 144402 | 228365_at | 1.0784 | 0.0548 | |
| GSE26886 | CPNE8 | 144402 | 228365_at | 1.3399 | 0.0268 | |
| GSE45670 | CPNE8 | 144402 | 228365_at | 1.1088 | 0.0001 | |
| GSE53622 | CPNE8 | 144402 | 78753 | 1.0302 | 0.0000 | |
| GSE53624 | CPNE8 | 144402 | 78753 | 1.1883 | 0.0000 | |
| GSE63941 | CPNE8 | 144402 | 228365_at | 0.2330 | 0.8652 | |
| GSE77861 | CPNE8 | 144402 | 241706_at | 1.0190 | 0.0026 | |
| GSE97050 | CPNE8 | 144402 | A_24_P56240 | 0.6348 | 0.1453 | |
| SRP007169 | CPNE8 | 144402 | RNAseq | 1.3619 | 0.0028 | |
| SRP008496 | CPNE8 | 144402 | RNAseq | 1.1461 | 0.0007 | |
| SRP064894 | CPNE8 | 144402 | RNAseq | 1.1840 | 0.0001 | |
| SRP133303 | CPNE8 | 144402 | RNAseq | 1.3560 | 0.0000 | |
| SRP159526 | CPNE8 | 144402 | RNAseq | 0.9294 | 0.0091 | |
| SRP193095 | CPNE8 | 144402 | RNAseq | 1.5150 | 0.0000 | |
| SRP219564 | CPNE8 | 144402 | RNAseq | 0.9988 | 0.0149 | |
| TCGA | CPNE8 | 144402 | RNAseq | 0.4197 | 0.0001 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by CPNE8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPNE8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPNE8 | 144402 | 7 | 1 | 22 | |
| GSE20123 | CPNE8 | 144402 | 7 | 1 | 22 | |
| GSE43470 | CPNE8 | 144402 | 7 | 3 | 33 | |
| GSE46452 | CPNE8 | 144402 | 8 | 1 | 50 | |
| GSE47630 | CPNE8 | 144402 | 11 | 2 | 27 | |
| GSE54993 | CPNE8 | 144402 | 1 | 8 | 61 | |
| GSE54994 | CPNE8 | 144402 | 6 | 1 | 46 | |
| GSE60625 | CPNE8 | 144402 | 0 | 0 | 11 | |
| GSE74703 | CPNE8 | 144402 | 6 | 2 | 28 | |
| GSE74704 | CPNE8 | 144402 | 3 | 1 | 16 | |
| TCGA | CPNE8 | 144402 | 39 | 5 | 52 |
Total number of gains: 95; Total number of losses: 25; Total Number of normals: 368.
Somatic mutations of CPNE8:
Generating mutation plots.
Highly correlated genes for CPNE8:
Showing top 20/1353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPNE8 | RAD21 | 0.907754 | 3 | 0 | 3 |
| CPNE8 | STX16 | 0.853317 | 3 | 0 | 3 |
| CPNE8 | CIAO1 | 0.824288 | 3 | 0 | 3 |
| CPNE8 | NOM1 | 0.818588 | 3 | 0 | 3 |
| CPNE8 | NOLC1 | 0.799207 | 3 | 0 | 3 |
| CPNE8 | ASXL1 | 0.792914 | 3 | 0 | 3 |
| CPNE8 | BORA | 0.781384 | 4 | 0 | 4 |
| CPNE8 | FAM161A | 0.776741 | 3 | 0 | 3 |
| CPNE8 | DSCC1 | 0.772189 | 4 | 0 | 3 |
| CPNE8 | PLEKHA3 | 0.770937 | 3 | 0 | 3 |
| CPNE8 | EPPK1 | 0.766907 | 5 | 0 | 5 |
| CPNE8 | TRMT61B | 0.76602 | 3 | 0 | 3 |
| CPNE8 | UXS1 | 0.765369 | 4 | 0 | 4 |
| CPNE8 | SGTB | 0.763484 | 3 | 0 | 3 |
| CPNE8 | KATNA1 | 0.761909 | 3 | 0 | 3 |
| CPNE8 | GPR153 | 0.761507 | 4 | 0 | 4 |
| CPNE8 | CBFA2T2 | 0.760659 | 3 | 0 | 3 |
| CPNE8 | INTS10 | 0.760476 | 3 | 0 | 3 |
| CPNE8 | LEMD3 | 0.747806 | 3 | 0 | 3 |
| CPNE8 | DOCK11 | 0.746624 | 3 | 0 | 3 |
For details and further investigation, click here
