| Full name: protein phosphatase 1 regulatory inhibitor subunit 14C | Alias Symbol: CPI17-like|NY-BR-81|KEPI | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 81706 | HGNC ID: HGNC:14952 | Ensembl Gene: ENSG00000198729 | OMIM ID: 613242 |
| Drug and gene relationship at DGIdb | |||
Expression of PPP1R14C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R14C | 81706 | 226907_at | 0.6664 | 0.5670 | |
| GSE26886 | PPP1R14C | 81706 | 226907_at | 0.6640 | 0.1408 | |
| GSE45670 | PPP1R14C | 81706 | 226907_at | 1.4389 | 0.0000 | |
| GSE53622 | PPP1R14C | 81706 | 87347 | 1.7516 | 0.0000 | |
| GSE53624 | PPP1R14C | 81706 | 87347 | 1.1927 | 0.0000 | |
| GSE63941 | PPP1R14C | 81706 | 226907_at | 3.0115 | 0.0023 | |
| GSE77861 | PPP1R14C | 81706 | 226907_at | 1.4040 | 0.0004 | |
| GSE97050 | PPP1R14C | 81706 | A_23_P45011 | 1.2185 | 0.1241 | |
| SRP007169 | PPP1R14C | 81706 | RNAseq | 1.6509 | 0.0000 | |
| SRP008496 | PPP1R14C | 81706 | RNAseq | 0.8418 | 0.0430 | |
| SRP064894 | PPP1R14C | 81706 | RNAseq | 1.0659 | 0.0099 | |
| SRP133303 | PPP1R14C | 81706 | RNAseq | 1.9245 | 0.0000 | |
| SRP159526 | PPP1R14C | 81706 | RNAseq | 2.1857 | 0.0025 | |
| SRP193095 | PPP1R14C | 81706 | RNAseq | 1.1753 | 0.0003 | |
| SRP219564 | PPP1R14C | 81706 | RNAseq | 0.5412 | 0.5985 | |
| TCGA | PPP1R14C | 81706 | RNAseq | 1.4711 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by PPP1R14C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP1R14C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R14C | 81706 | 2 | 4 | 24 | |
| GSE20123 | PPP1R14C | 81706 | 2 | 3 | 25 | |
| GSE43470 | PPP1R14C | 81706 | 4 | 0 | 39 | |
| GSE46452 | PPP1R14C | 81706 | 3 | 10 | 46 | |
| GSE47630 | PPP1R14C | 81706 | 9 | 4 | 27 | |
| GSE54993 | PPP1R14C | 81706 | 3 | 2 | 65 | |
| GSE54994 | PPP1R14C | 81706 | 8 | 8 | 37 | |
| GSE60625 | PPP1R14C | 81706 | 0 | 1 | 10 | |
| GSE74703 | PPP1R14C | 81706 | 4 | 0 | 32 | |
| GSE74704 | PPP1R14C | 81706 | 0 | 1 | 19 | |
| TCGA | PPP1R14C | 81706 | 12 | 20 | 64 |
Total number of gains: 47; Total number of losses: 53; Total Number of normals: 388.
Somatic mutations of PPP1R14C:
Generating mutation plots.
Highly correlated genes for PPP1R14C:
Showing top 20/995 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R14C | EPPK1 | 0.829641 | 3 | 0 | 3 |
| PPP1R14C | UBE2S | 0.743986 | 3 | 0 | 3 |
| PPP1R14C | CCT5 | 0.732911 | 4 | 0 | 4 |
| PPP1R14C | CDH3 | 0.731484 | 7 | 0 | 7 |
| PPP1R14C | MYO10 | 0.73063 | 4 | 0 | 3 |
| PPP1R14C | TUBA1C | 0.728271 | 3 | 0 | 3 |
| PPP1R14C | KIF2C | 0.721818 | 7 | 0 | 6 |
| PPP1R14C | CDC6 | 0.718815 | 5 | 0 | 5 |
| PPP1R14C | PPP3CA | 0.718707 | 3 | 0 | 3 |
| PPP1R14C | NUP210 | 0.716841 | 3 | 0 | 3 |
| PPP1R14C | PTTG1 | 0.714088 | 7 | 0 | 6 |
| PPP1R14C | CDCA8 | 0.710593 | 6 | 0 | 6 |
| PPP1R14C | RPS6KA1 | 0.708385 | 6 | 0 | 6 |
| PPP1R14C | STK17A | 0.708123 | 4 | 0 | 4 |
| PPP1R14C | DCBLD1 | 0.707793 | 7 | 0 | 6 |
| PPP1R14C | PLCG2 | 0.7075 | 4 | 0 | 4 |
| PPP1R14C | TENM2 | 0.705216 | 6 | 0 | 6 |
| PPP1R14C | RNASEH2A | 0.703658 | 6 | 0 | 5 |
| PPP1R14C | MCM4 | 0.702704 | 8 | 0 | 8 |
| PPP1R14C | RCC2 | 0.701493 | 6 | 0 | 5 |
For details and further investigation, click here
