| Full name: family with sequence similarity 110 member B | Alias Symbol: MGC39325 | ||
| Type: protein-coding gene | Cytoband: 8q12.1 | ||
| Entrez ID: 90362 | HGNC ID: HGNC:28587 | Ensembl Gene: ENSG00000169122 | OMIM ID: 611394 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM110B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM110B | 90362 | 221959_at | -0.4727 | 0.4137 | |
| GSE20347 | FAM110B | 90362 | 221959_at | 0.0271 | 0.7789 | |
| GSE23400 | FAM110B | 90362 | 221959_at | -0.0816 | 0.0546 | |
| GSE26886 | FAM110B | 90362 | 221959_at | 0.8103 | 0.0040 | |
| GSE29001 | FAM110B | 90362 | 221959_at | -0.1500 | 0.4201 | |
| GSE38129 | FAM110B | 90362 | 221959_at | -0.2234 | 0.2529 | |
| GSE45670 | FAM110B | 90362 | 221959_at | -0.4101 | 0.0012 | |
| GSE63941 | FAM110B | 90362 | 221959_at | -2.2456 | 0.0000 | |
| GSE77861 | FAM110B | 90362 | 227800_at | -0.1778 | 0.1050 | |
| GSE97050 | FAM110B | 90362 | A_33_P3330443 | -0.1903 | 0.5456 | |
| SRP064894 | FAM110B | 90362 | RNAseq | 0.3293 | 0.3936 | |
| SRP133303 | FAM110B | 90362 | RNAseq | -0.3807 | 0.1801 | |
| SRP159526 | FAM110B | 90362 | RNAseq | 0.7505 | 0.0551 | |
| SRP219564 | FAM110B | 90362 | RNAseq | -0.0325 | 0.9620 | |
| TCGA | FAM110B | 90362 | RNAseq | -0.8896 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FAM110B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FAM110B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM110B | 90362 | 13 | 1 | 16 | |
| GSE20123 | FAM110B | 90362 | 13 | 1 | 16 | |
| GSE43470 | FAM110B | 90362 | 13 | 3 | 27 | |
| GSE46452 | FAM110B | 90362 | 20 | 3 | 36 | |
| GSE47630 | FAM110B | 90362 | 23 | 1 | 16 | |
| GSE54993 | FAM110B | 90362 | 1 | 17 | 52 | |
| GSE54994 | FAM110B | 90362 | 30 | 0 | 23 | |
| GSE60625 | FAM110B | 90362 | 0 | 4 | 7 | |
| GSE74703 | FAM110B | 90362 | 12 | 2 | 22 | |
| GSE74704 | FAM110B | 90362 | 9 | 0 | 11 | |
| TCGA | FAM110B | 90362 | 44 | 6 | 46 |
Total number of gains: 178; Total number of losses: 38; Total Number of normals: 272.
Somatic mutations of FAM110B:
Generating mutation plots.
Highly correlated genes for FAM110B:
Showing top 20/287 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM110B | SCARA5 | 0.844112 | 3 | 0 | 3 |
| FAM110B | MAPK8IP1 | 0.832617 | 3 | 0 | 3 |
| FAM110B | GALNT15 | 0.793946 | 3 | 0 | 3 |
| FAM110B | TCEAL7 | 0.783262 | 4 | 0 | 4 |
| FAM110B | SVOPL | 0.755794 | 3 | 0 | 3 |
| FAM110B | LRTM2 | 0.751608 | 3 | 0 | 3 |
| FAM110B | RGL4 | 0.749978 | 3 | 0 | 3 |
| FAM110B | ATOH8 | 0.745844 | 3 | 0 | 3 |
| FAM110B | ZNF781 | 0.745559 | 3 | 0 | 3 |
| FAM110B | SLC45A1 | 0.740522 | 3 | 0 | 3 |
| FAM110B | ZCCHC18 | 0.735211 | 5 | 0 | 4 |
| FAM110B | TRIM10 | 0.732232 | 3 | 0 | 3 |
| FAM110B | MC3R | 0.731864 | 3 | 0 | 3 |
| FAM110B | CNTN4 | 0.731783 | 4 | 0 | 4 |
| FAM110B | LINC01082 | 0.731742 | 3 | 0 | 3 |
| FAM110B | DNM3OS | 0.723827 | 3 | 0 | 3 |
| FAM110B | GDF15 | 0.723157 | 3 | 0 | 3 |
| FAM110B | TSPAN11 | 0.716349 | 3 | 0 | 3 |
| FAM110B | BAHCC1 | 0.711417 | 4 | 0 | 4 |
| FAM110B | RASGRF2 | 0.710658 | 4 | 0 | 4 |
For details and further investigation, click here
