| Full name: atonal bHLH transcription factor 8 | Alias Symbol: HATH6|FLJ14708|bHLHa21 | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 84913 | HGNC ID: HGNC:24126 | Ensembl Gene: ENSG00000168874 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ATOH8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATOH8 | 84913 | 1558705_at | -0.1659 | 0.5611 | |
| GSE26886 | ATOH8 | 84913 | 1558705_at | -0.2207 | 0.1078 | |
| GSE45670 | ATOH8 | 84913 | 1558705_at | -0.0740 | 0.3390 | |
| GSE53622 | ATOH8 | 84913 | 91250 | -2.2012 | 0.0000 | |
| GSE53624 | ATOH8 | 84913 | 91250 | -1.9907 | 0.0000 | |
| GSE63941 | ATOH8 | 84913 | 228890_at | -2.8945 | 0.0000 | |
| GSE77861 | ATOH8 | 84913 | 1558705_at | -0.0226 | 0.8028 | |
| GSE97050 | ATOH8 | 84913 | A_33_P3392740 | -0.7299 | 0.0684 | |
| SRP064894 | ATOH8 | 84913 | RNAseq | -0.4939 | 0.3960 | |
| SRP133303 | ATOH8 | 84913 | RNAseq | -2.1095 | 0.0002 | |
| SRP159526 | ATOH8 | 84913 | RNAseq | -1.7504 | 0.0000 | |
| SRP219564 | ATOH8 | 84913 | RNAseq | -1.2032 | 0.1974 | |
| TCGA | ATOH8 | 84913 | RNAseq | -1.5596 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ATOH8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATOH8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATOH8 | 84913 | 9 | 2 | 19 | |
| GSE20123 | ATOH8 | 84913 | 9 | 2 | 19 | |
| GSE43470 | ATOH8 | 84913 | 6 | 2 | 35 | |
| GSE46452 | ATOH8 | 84913 | 2 | 3 | 54 | |
| GSE47630 | ATOH8 | 84913 | 7 | 0 | 33 | |
| GSE54993 | ATOH8 | 84913 | 0 | 6 | 64 | |
| GSE54994 | ATOH8 | 84913 | 10 | 0 | 43 | |
| GSE60625 | ATOH8 | 84913 | 0 | 3 | 8 | |
| GSE74703 | ATOH8 | 84913 | 5 | 1 | 30 | |
| GSE74704 | ATOH8 | 84913 | 7 | 0 | 13 | |
| TCGA | ATOH8 | 84913 | 35 | 4 | 57 |
Total number of gains: 90; Total number of losses: 23; Total Number of normals: 375.
Somatic mutations of ATOH8:
Generating mutation plots.
Highly correlated genes for ATOH8:
Showing top 20/472 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATOH8 | LINC01082 | 0.805266 | 4 | 0 | 4 |
| ATOH8 | RCAN2 | 0.781889 | 4 | 0 | 4 |
| ATOH8 | ZCWPW2 | 0.778009 | 3 | 0 | 3 |
| ATOH8 | WFDC1 | 0.777856 | 4 | 0 | 4 |
| ATOH8 | ZNF569 | 0.766973 | 3 | 0 | 3 |
| ATOH8 | MRVI1 | 0.765149 | 4 | 0 | 4 |
| ATOH8 | CBX7 | 0.755897 | 3 | 0 | 3 |
| ATOH8 | FAM110B | 0.745844 | 3 | 0 | 3 |
| ATOH8 | RAB3C | 0.742605 | 3 | 0 | 3 |
| ATOH8 | TNXB | 0.742141 | 4 | 0 | 3 |
| ATOH8 | SHC3 | 0.739358 | 5 | 0 | 4 |
| ATOH8 | PYGM | 0.736538 | 3 | 0 | 3 |
| ATOH8 | PCP4 | 0.732093 | 3 | 0 | 3 |
| ATOH8 | IL6ST | 0.729194 | 4 | 0 | 4 |
| ATOH8 | SCN3A | 0.723474 | 4 | 0 | 4 |
| ATOH8 | ZDHHC15 | 0.722394 | 4 | 0 | 4 |
| ATOH8 | ABLIM3 | 0.717692 | 4 | 0 | 4 |
| ATOH8 | C1QTNF2 | 0.716904 | 4 | 0 | 4 |
| ATOH8 | ENTPD1 | 0.712659 | 3 | 0 | 3 |
| ATOH8 | ACTG2 | 0.711744 | 4 | 0 | 4 |
For details and further investigation, click here
