| Full name: family with sequence similarity 3 member C | Alias Symbol: GS3876|ILEI | ||
| Type: protein-coding gene | Cytoband: 7q31.31 | ||
| Entrez ID: 10447 | HGNC ID: HGNC:18664 | Ensembl Gene: ENSG00000196937 | OMIM ID: 608618 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM3C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM3C | 10447 | 201889_at | -0.0695 | 0.9263 | |
| GSE20347 | FAM3C | 10447 | 201889_at | 0.4220 | 0.0355 | |
| GSE23400 | FAM3C | 10447 | 201889_at | 0.7082 | 0.0000 | |
| GSE26886 | FAM3C | 10447 | 201889_at | 0.3186 | 0.3840 | |
| GSE29001 | FAM3C | 10447 | 201889_at | 0.4638 | 0.2463 | |
| GSE38129 | FAM3C | 10447 | 201889_at | 0.5526 | 0.0001 | |
| GSE45670 | FAM3C | 10447 | 201889_at | 0.5355 | 0.0396 | |
| GSE53622 | FAM3C | 10447 | 97838 | 0.6774 | 0.0000 | |
| GSE53624 | FAM3C | 10447 | 42152 | 0.7414 | 0.0000 | |
| GSE63941 | FAM3C | 10447 | 201889_at | -0.2322 | 0.7629 | |
| GSE77861 | FAM3C | 10447 | 201889_at | 0.5473 | 0.2167 | |
| GSE97050 | FAM3C | A_21_P0013755 | 0.7624 | 0.1033 | ||
| SRP007169 | FAM3C | 10447 | RNAseq | 1.8964 | 0.0000 | |
| SRP008496 | FAM3C | 10447 | RNAseq | 1.8176 | 0.0000 | |
| SRP064894 | FAM3C | 10447 | RNAseq | 0.9007 | 0.0000 | |
| SRP133303 | FAM3C | 10447 | RNAseq | 1.2445 | 0.0000 | |
| SRP159526 | FAM3C | 10447 | RNAseq | 0.5100 | 0.1995 | |
| SRP193095 | FAM3C | 10447 | RNAseq | 0.1118 | 0.5429 | |
| SRP219564 | FAM3C | 10447 | RNAseq | 0.6046 | 0.0944 | |
| TCGA | FAM3C | 10447 | RNAseq | -0.0381 | 0.5186 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by FAM3C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM3C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM3C | 10447 | 7 | 2 | 21 | |
| GSE20123 | FAM3C | 10447 | 8 | 2 | 20 | |
| GSE43470 | FAM3C | 10447 | 3 | 3 | 37 | |
| GSE46452 | FAM3C | 10447 | 8 | 1 | 50 | |
| GSE47630 | FAM3C | 10447 | 7 | 4 | 29 | |
| GSE54993 | FAM3C | 10447 | 2 | 6 | 62 | |
| GSE54994 | FAM3C | 10447 | 10 | 6 | 37 | |
| GSE60625 | FAM3C | 10447 | 0 | 0 | 11 | |
| GSE74703 | FAM3C | 10447 | 3 | 3 | 30 | |
| GSE74704 | FAM3C | 10447 | 5 | 2 | 13 | |
| TCGA | FAM3C | 10447 | 28 | 20 | 48 |
Total number of gains: 81; Total number of losses: 49; Total Number of normals: 358.
Somatic mutations of FAM3C:
Generating mutation plots.
Highly correlated genes for FAM3C:
Showing top 20/874 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM3C | ANKRD50 | 0.778208 | 3 | 0 | 3 |
| FAM3C | ATG4C | 0.775588 | 3 | 0 | 3 |
| FAM3C | WDR92 | 0.749117 | 3 | 0 | 3 |
| FAM3C | FGFR1OP2 | 0.745078 | 3 | 0 | 3 |
| FAM3C | PYCR2 | 0.737328 | 3 | 0 | 3 |
| FAM3C | RHBDD1 | 0.722273 | 3 | 0 | 3 |
| FAM3C | C12orf45 | 0.718792 | 3 | 0 | 3 |
| FAM3C | ZW10 | 0.717898 | 3 | 0 | 3 |
| FAM3C | SWAP70 | 0.713243 | 3 | 0 | 3 |
| FAM3C | ACBD5 | 0.712194 | 3 | 0 | 3 |
| FAM3C | FAM160B1 | 0.711848 | 3 | 0 | 3 |
| FAM3C | KBTBD4 | 0.705322 | 4 | 0 | 4 |
| FAM3C | CEP44 | 0.703857 | 3 | 0 | 3 |
| FAM3C | ZNF764 | 0.703523 | 3 | 0 | 3 |
| FAM3C | ZFC3H1 | 0.703502 | 3 | 0 | 3 |
| FAM3C | ANAPC1 | 0.698799 | 3 | 0 | 3 |
| FAM3C | VMA21 | 0.695835 | 4 | 0 | 3 |
| FAM3C | ATP11B | 0.693241 | 3 | 0 | 3 |
| FAM3C | TSPAN9 | 0.69216 | 3 | 0 | 3 |
| FAM3C | UBE2O | 0.689813 | 3 | 0 | 3 |
For details and further investigation, click here
