| Full name: FGFR1 oncogene partner 2 | Alias Symbol: DKFZp564O1863 | ||
| Type: protein-coding gene | Cytoband: 12p11.23 | ||
| Entrez ID: 26127 | HGNC ID: HGNC:23098 | Ensembl Gene: ENSG00000111790 | OMIM ID: 608858 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FGFR1OP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGFR1OP2 | 26127 | 233898_s_at | -0.0369 | 0.9548 | |
| GSE26886 | FGFR1OP2 | 26127 | 233898_s_at | -0.8905 | 0.0211 | |
| GSE45670 | FGFR1OP2 | 26127 | 233898_s_at | -0.2544 | 0.0882 | |
| GSE53622 | FGFR1OP2 | 26127 | 55993 | 0.2950 | 0.0000 | |
| GSE53624 | FGFR1OP2 | 26127 | 55993 | 0.3879 | 0.0000 | |
| GSE63941 | FGFR1OP2 | 26127 | 233898_s_at | -0.3427 | 0.6461 | |
| GSE77861 | FGFR1OP2 | 26127 | 223262_s_at | -0.0227 | 0.8050 | |
| GSE97050 | FGFR1OP2 | 26127 | A_33_P3369258 | 0.4344 | 0.2204 | |
| SRP007169 | FGFR1OP2 | 26127 | RNAseq | 0.3740 | 0.4029 | |
| SRP008496 | FGFR1OP2 | 26127 | RNAseq | 0.9204 | 0.0103 | |
| SRP064894 | FGFR1OP2 | 26127 | RNAseq | -0.1724 | 0.2512 | |
| SRP133303 | FGFR1OP2 | 26127 | RNAseq | 0.3877 | 0.0103 | |
| SRP159526 | FGFR1OP2 | 26127 | RNAseq | -0.3374 | 0.0964 | |
| SRP193095 | FGFR1OP2 | 26127 | RNAseq | -0.0411 | 0.8025 | |
| SRP219564 | FGFR1OP2 | 26127 | RNAseq | -0.0125 | 0.9755 | |
| TCGA | FGFR1OP2 | 26127 | RNAseq | 0.0272 | 0.6323 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FGFR1OP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGFR1OP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGFR1OP2 | 26127 | 10 | 1 | 19 | |
| GSE20123 | FGFR1OP2 | 26127 | 10 | 1 | 19 | |
| GSE43470 | FGFR1OP2 | 26127 | 9 | 4 | 30 | |
| GSE46452 | FGFR1OP2 | 26127 | 10 | 1 | 48 | |
| GSE47630 | FGFR1OP2 | 26127 | 14 | 0 | 26 | |
| GSE54993 | FGFR1OP2 | 26127 | 0 | 9 | 61 | |
| GSE54994 | FGFR1OP2 | 26127 | 10 | 3 | 40 | |
| GSE60625 | FGFR1OP2 | 26127 | 0 | 1 | 10 | |
| GSE74703 | FGFR1OP2 | 26127 | 9 | 3 | 24 | |
| GSE74704 | FGFR1OP2 | 26127 | 5 | 1 | 14 | |
| TCGA | FGFR1OP2 | 26127 | 43 | 6 | 47 |
Total number of gains: 120; Total number of losses: 30; Total Number of normals: 338.
Somatic mutations of FGFR1OP2:
Generating mutation plots.
Highly correlated genes for FGFR1OP2:
Showing top 20/161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGFR1OP2 | AP3M1 | 0.788221 | 3 | 0 | 3 |
| FGFR1OP2 | DOCK1 | 0.774951 | 3 | 0 | 3 |
| FGFR1OP2 | TMEM30A | 0.768481 | 3 | 0 | 3 |
| FGFR1OP2 | SENP2 | 0.757624 | 3 | 0 | 3 |
| FGFR1OP2 | LMBRD2 | 0.754397 | 3 | 0 | 3 |
| FGFR1OP2 | FAM3C | 0.745078 | 3 | 0 | 3 |
| FGFR1OP2 | WDR92 | 0.739239 | 3 | 0 | 3 |
| FGFR1OP2 | TMEM150C | 0.738315 | 3 | 0 | 3 |
| FGFR1OP2 | GLCE | 0.732867 | 3 | 0 | 3 |
| FGFR1OP2 | LRP6 | 0.730039 | 4 | 0 | 4 |
| FGFR1OP2 | KAT7 | 0.729496 | 3 | 0 | 3 |
| FGFR1OP2 | RNF146 | 0.728684 | 3 | 0 | 3 |
| FGFR1OP2 | PRMT6 | 0.727076 | 3 | 0 | 3 |
| FGFR1OP2 | SRP68 | 0.71577 | 3 | 0 | 3 |
| FGFR1OP2 | ZNF33A | 0.709936 | 3 | 0 | 3 |
| FGFR1OP2 | USP34 | 0.709482 | 3 | 0 | 3 |
| FGFR1OP2 | NPAT | 0.704577 | 3 | 0 | 3 |
| FGFR1OP2 | ELAC1 | 0.694419 | 3 | 0 | 3 |
| FGFR1OP2 | ING4 | 0.692914 | 4 | 0 | 4 |
| FGFR1OP2 | FGF7 | 0.690178 | 3 | 0 | 3 |
For details and further investigation, click here
