| Full name: switching B cell complex subunit SWAP70 | Alias Symbol: KIAA0640|SWAP-70 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 23075 | HGNC ID: HGNC:17070 | Ensembl Gene: ENSG00000133789 | OMIM ID: 604762 |
| Drug and gene relationship at DGIdb | |||
Expression of SWAP70:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SWAP70 | 23075 | 209306_s_at | -0.2012 | 0.7676 | |
| GSE20347 | SWAP70 | 23075 | 209306_s_at | -0.3046 | 0.1726 | |
| GSE23400 | SWAP70 | 23075 | 210369_at | 0.0133 | 0.7801 | |
| GSE26886 | SWAP70 | 23075 | 209306_s_at | -0.1926 | 0.5816 | |
| GSE29001 | SWAP70 | 23075 | 209307_at | 0.4986 | 0.2219 | |
| GSE38129 | SWAP70 | 23075 | 209306_s_at | -0.2211 | 0.2165 | |
| GSE45670 | SWAP70 | 23075 | 209306_s_at | -0.0516 | 0.7860 | |
| GSE53622 | SWAP70 | 23075 | 19991 | 0.0390 | 0.6789 | |
| GSE53624 | SWAP70 | 23075 | 19991 | 0.2668 | 0.0070 | |
| GSE63941 | SWAP70 | 23075 | 209307_at | -1.8629 | 0.0182 | |
| GSE77861 | SWAP70 | 23075 | 209306_s_at | 0.1151 | 0.7957 | |
| GSE97050 | SWAP70 | 23075 | A_33_P3349651 | 0.0530 | 0.8078 | |
| SRP007169 | SWAP70 | 23075 | RNAseq | 0.3737 | 0.4586 | |
| SRP008496 | SWAP70 | 23075 | RNAseq | 0.6570 | 0.0610 | |
| SRP064894 | SWAP70 | 23075 | RNAseq | -0.0311 | 0.8908 | |
| SRP133303 | SWAP70 | 23075 | RNAseq | 0.0573 | 0.7760 | |
| SRP159526 | SWAP70 | 23075 | RNAseq | -0.3811 | 0.3356 | |
| SRP193095 | SWAP70 | 23075 | RNAseq | 0.2283 | 0.0944 | |
| SRP219564 | SWAP70 | 23075 | RNAseq | -0.1520 | 0.6193 | |
| TCGA | SWAP70 | 23075 | RNAseq | 0.0522 | 0.2954 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SWAP70 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SWAP70:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SWAP70 | 23075 | 0 | 9 | 21 | |
| GSE20123 | SWAP70 | 23075 | 0 | 9 | 21 | |
| GSE43470 | SWAP70 | 23075 | 1 | 6 | 36 | |
| GSE46452 | SWAP70 | 23075 | 7 | 5 | 47 | |
| GSE47630 | SWAP70 | 23075 | 3 | 11 | 26 | |
| GSE54993 | SWAP70 | 23075 | 3 | 1 | 66 | |
| GSE54994 | SWAP70 | 23075 | 3 | 12 | 38 | |
| GSE60625 | SWAP70 | 23075 | 0 | 0 | 11 | |
| GSE74703 | SWAP70 | 23075 | 1 | 4 | 31 | |
| GSE74704 | SWAP70 | 23075 | 0 | 7 | 13 | |
| TCGA | SWAP70 | 23075 | 11 | 34 | 51 |
Total number of gains: 29; Total number of losses: 98; Total Number of normals: 361.
Somatic mutations of SWAP70:
Generating mutation plots.
Highly correlated genes for SWAP70:
Showing top 20/321 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SWAP70 | CD2BP2 | 0.823039 | 3 | 0 | 3 |
| SWAP70 | USP8 | 0.79274 | 3 | 0 | 3 |
| SWAP70 | CIB1 | 0.789469 | 3 | 0 | 3 |
| SWAP70 | IMP3 | 0.767206 | 3 | 0 | 3 |
| SWAP70 | PRDM4 | 0.765543 | 3 | 0 | 3 |
| SWAP70 | NAP1L4 | 0.75514 | 3 | 0 | 3 |
| SWAP70 | BECN1 | 0.749323 | 3 | 0 | 3 |
| SWAP70 | SEC23IP | 0.748144 | 3 | 0 | 3 |
| SWAP70 | BDKRB2 | 0.747325 | 3 | 0 | 3 |
| SWAP70 | TK2 | 0.741739 | 3 | 0 | 3 |
| SWAP70 | TOMM22 | 0.741207 | 3 | 0 | 3 |
| SWAP70 | FHOD3 | 0.740783 | 3 | 0 | 3 |
| SWAP70 | SRBD1 | 0.732337 | 3 | 0 | 3 |
| SWAP70 | SLC25A24 | 0.723898 | 3 | 0 | 3 |
| SWAP70 | NIF3L1 | 0.722924 | 3 | 0 | 3 |
| SWAP70 | ARIH1 | 0.722358 | 4 | 0 | 3 |
| SWAP70 | ATF1 | 0.71964 | 4 | 0 | 4 |
| SWAP70 | VPS13C | 0.719275 | 3 | 0 | 3 |
| SWAP70 | FAM3C | 0.713243 | 3 | 0 | 3 |
| SWAP70 | RPS6KB1 | 0.712348 | 3 | 0 | 3 |
For details and further investigation, click here
