| Full name: ankyrin repeat domain 50 | Alias Symbol: KIAA1223 | ||
| Type: protein-coding gene | Cytoband: 4q28.1 | ||
| Entrez ID: 57182 | HGNC ID: HGNC:29223 | Ensembl Gene: ENSG00000151458 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD50:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD50 | 57182 | 225731_at | 0.2075 | 0.7321 | |
| GSE26886 | ANKRD50 | 57182 | 225731_at | 0.1660 | 0.5986 | |
| GSE45670 | ANKRD50 | 57182 | 225731_at | -0.0231 | 0.9045 | |
| GSE53622 | ANKRD50 | 57182 | 8453 | 0.1459 | 0.1700 | |
| GSE53624 | ANKRD50 | 57182 | 8453 | 0.0682 | 0.6631 | |
| GSE63941 | ANKRD50 | 57182 | 225731_at | -1.0288 | 0.1715 | |
| GSE77861 | ANKRD50 | 57182 | 225731_at | 0.3400 | 0.3145 | |
| GSE97050 | ANKRD50 | 57182 | A_33_P3231140 | 0.2339 | 0.3721 | |
| SRP007169 | ANKRD50 | 57182 | RNAseq | 1.2397 | 0.0035 | |
| SRP008496 | ANKRD50 | 57182 | RNAseq | 1.3295 | 0.0000 | |
| SRP064894 | ANKRD50 | 57182 | RNAseq | 0.4180 | 0.0939 | |
| SRP133303 | ANKRD50 | 57182 | RNAseq | 0.7146 | 0.0000 | |
| SRP159526 | ANKRD50 | 57182 | RNAseq | 0.0381 | 0.9063 | |
| SRP193095 | ANKRD50 | 57182 | RNAseq | 0.1966 | 0.1969 | |
| SRP219564 | ANKRD50 | 57182 | RNAseq | -0.0368 | 0.9206 | |
| TCGA | ANKRD50 | 57182 | RNAseq | 0.0067 | 0.9180 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ANKRD50 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD50:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD50 | 57182 | 0 | 12 | 18 | |
| GSE20123 | ANKRD50 | 57182 | 0 | 12 | 18 | |
| GSE43470 | ANKRD50 | 57182 | 0 | 14 | 29 | |
| GSE46452 | ANKRD50 | 57182 | 1 | 36 | 22 | |
| GSE47630 | ANKRD50 | 57182 | 0 | 22 | 18 | |
| GSE54993 | ANKRD50 | 57182 | 9 | 0 | 61 | |
| GSE54994 | ANKRD50 | 57182 | 1 | 10 | 42 | |
| GSE60625 | ANKRD50 | 57182 | 0 | 1 | 10 | |
| GSE74703 | ANKRD50 | 57182 | 0 | 12 | 24 | |
| GSE74704 | ANKRD50 | 57182 | 0 | 6 | 14 | |
| TCGA | ANKRD50 | 57182 | 8 | 35 | 53 |
Total number of gains: 19; Total number of losses: 160; Total Number of normals: 309.
Somatic mutations of ANKRD50:
Generating mutation plots.
Highly correlated genes for ANKRD50:
Showing top 20/217 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD50 | PPP6R3 | 0.833494 | 3 | 0 | 3 |
| ANKRD50 | SLC25A36 | 0.795281 | 3 | 0 | 3 |
| ANKRD50 | FAM3C | 0.778208 | 3 | 0 | 3 |
| ANKRD50 | STEAP1 | 0.76338 | 3 | 0 | 3 |
| ANKRD50 | ADAM10 | 0.76278 | 4 | 0 | 4 |
| ANKRD50 | TXNDC16 | 0.76191 | 3 | 0 | 3 |
| ANKRD50 | ACTR2 | 0.760587 | 3 | 0 | 3 |
| ANKRD50 | LRRC47 | 0.75975 | 3 | 0 | 3 |
| ANKRD50 | EXOC8 | 0.755818 | 3 | 0 | 3 |
| ANKRD50 | SMC5 | 0.748007 | 3 | 0 | 3 |
| ANKRD50 | EID1 | 0.740766 | 3 | 0 | 3 |
| ANKRD50 | TRIAP1 | 0.738667 | 3 | 0 | 3 |
| ANKRD50 | PSMD2 | 0.724234 | 3 | 0 | 3 |
| ANKRD50 | JAG1 | 0.722425 | 3 | 0 | 3 |
| ANKRD50 | SMAD3 | 0.720543 | 3 | 0 | 3 |
| ANKRD50 | SNRPA1 | 0.720431 | 3 | 0 | 3 |
| ANKRD50 | PEX2 | 0.71624 | 3 | 0 | 3 |
| ANKRD50 | PLEKHB2 | 0.714746 | 4 | 0 | 3 |
| ANKRD50 | CTDSPL2 | 0.712946 | 3 | 0 | 3 |
| ANKRD50 | DTWD1 | 0.711122 | 3 | 0 | 3 |
For details and further investigation, click here
