| Full name: autophagy related 4C cysteine peptidase | Alias Symbol: FLJ14867|AUTL3 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 84938 | HGNC ID: HGNC:16040 | Ensembl Gene: ENSG00000125703 | OMIM ID: 611339 |
| Drug and gene relationship at DGIdb | |||
Expression of ATG4C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG4C | 84938 | 228190_at | 0.3612 | 0.5789 | |
| GSE26886 | ATG4C | 84938 | 228190_at | -0.3572 | 0.1820 | |
| GSE45670 | ATG4C | 84938 | 228190_at | 0.2400 | 0.2518 | |
| GSE53622 | ATG4C | 84938 | 127258 | 0.1683 | 0.0544 | |
| GSE53624 | ATG4C | 84938 | 127258 | 0.2889 | 0.0083 | |
| GSE63941 | ATG4C | 84938 | 228190_at | -0.3443 | 0.3781 | |
| GSE77861 | ATG4C | 84938 | 228190_at | -0.1031 | 0.4421 | |
| GSE97050 | ATG4C | 84938 | A_33_P3396807 | 0.3047 | 0.3094 | |
| SRP007169 | ATG4C | 84938 | RNAseq | 0.1602 | 0.7601 | |
| SRP008496 | ATG4C | 84938 | RNAseq | 0.0597 | 0.8679 | |
| SRP064894 | ATG4C | 84938 | RNAseq | 0.5111 | 0.0013 | |
| SRP133303 | ATG4C | 84938 | RNAseq | 0.3373 | 0.0785 | |
| SRP159526 | ATG4C | 84938 | RNAseq | -0.2561 | 0.3174 | |
| SRP193095 | ATG4C | 84938 | RNAseq | -0.2312 | 0.0590 | |
| SRP219564 | ATG4C | 84938 | RNAseq | 0.3707 | 0.3026 | |
| TCGA | ATG4C | 84938 | RNAseq | -0.0820 | 0.2810 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATG4C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATG4C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG4C | 84938 | 3 | 6 | 21 | |
| GSE20123 | ATG4C | 84938 | 3 | 5 | 22 | |
| GSE43470 | ATG4C | 84938 | 5 | 4 | 34 | |
| GSE46452 | ATG4C | 84938 | 1 | 1 | 57 | |
| GSE47630 | ATG4C | 84938 | 8 | 5 | 27 | |
| GSE54993 | ATG4C | 84938 | 0 | 0 | 70 | |
| GSE54994 | ATG4C | 84938 | 6 | 4 | 43 | |
| GSE60625 | ATG4C | 84938 | 0 | 0 | 11 | |
| GSE74703 | ATG4C | 84938 | 4 | 3 | 29 | |
| GSE74704 | ATG4C | 84938 | 2 | 2 | 16 | |
| TCGA | ATG4C | 84938 | 10 | 20 | 66 |
Total number of gains: 42; Total number of losses: 50; Total Number of normals: 396.
Somatic mutations of ATG4C:
Generating mutation plots.
Highly correlated genes for ATG4C:
Showing top 20/372 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG4C | TEX261 | 0.843508 | 3 | 0 | 3 |
| ATG4C | COMMD7 | 0.840079 | 3 | 0 | 3 |
| ATG4C | DHPS | 0.827201 | 3 | 0 | 3 |
| ATG4C | ZNF317 | 0.823163 | 3 | 0 | 3 |
| ATG4C | C9orf78 | 0.821872 | 3 | 0 | 3 |
| ATG4C | BOLA1 | 0.819187 | 3 | 0 | 3 |
| ATG4C | FOXJ2 | 0.79323 | 3 | 0 | 3 |
| ATG4C | MRPS34 | 0.788794 | 3 | 0 | 3 |
| ATG4C | PSMC3 | 0.785149 | 4 | 0 | 4 |
| ATG4C | NAA30 | 0.783565 | 3 | 0 | 3 |
| ATG4C | FAM3C | 0.775588 | 3 | 0 | 3 |
| ATG4C | ANKIB1 | 0.774553 | 3 | 0 | 3 |
| ATG4C | STX10 | 0.772945 | 3 | 0 | 3 |
| ATG4C | ZFAND1 | 0.772069 | 3 | 0 | 3 |
| ATG4C | FN3KRP | 0.771199 | 3 | 0 | 3 |
| ATG4C | MRPL44 | 0.770644 | 3 | 0 | 3 |
| ATG4C | TMEM216 | 0.764569 | 3 | 0 | 3 |
| ATG4C | PEMT | 0.761412 | 3 | 0 | 3 |
| ATG4C | BABAM1 | 0.760529 | 3 | 0 | 3 |
| ATG4C | CHMP7 | 0.759353 | 3 | 0 | 3 |
For details and further investigation, click here
