| Full name: ubiquitin conjugating enzyme E2 O | Alias Symbol: E2-230K | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 63893 | HGNC ID: HGNC:29554 | Ensembl Gene: ENSG00000175931 | OMIM ID: 617649 |
| Drug and gene relationship at DGIdb | |||
Expression of UBE2O:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2O | 63893 | 218141_at | 0.5740 | 0.1116 | |
| GSE20347 | UBE2O | 63893 | 218141_at | 0.4904 | 0.0001 | |
| GSE23400 | UBE2O | 63893 | 218141_at | 0.2006 | 0.0000 | |
| GSE26886 | UBE2O | 63893 | 218141_at | 0.2149 | 0.2050 | |
| GSE29001 | UBE2O | 63893 | 218141_at | 0.1738 | 0.4194 | |
| GSE38129 | UBE2O | 63893 | 218141_at | 0.4210 | 0.0000 | |
| GSE45670 | UBE2O | 63893 | 218141_at | 0.5091 | 0.0006 | |
| GSE53622 | UBE2O | 63893 | 139019 | 0.4941 | 0.0000 | |
| GSE53624 | UBE2O | 63893 | 139019 | 0.6800 | 0.0000 | |
| GSE63941 | UBE2O | 63893 | 218141_at | 0.0821 | 0.7746 | |
| GSE77861 | UBE2O | 63893 | 1554814_at | -0.0389 | 0.7690 | |
| GSE97050 | UBE2O | 63893 | A_24_P172993 | 0.2039 | 0.3817 | |
| SRP007169 | UBE2O | 63893 | RNAseq | 2.3394 | 0.0000 | |
| SRP008496 | UBE2O | 63893 | RNAseq | 1.7092 | 0.0000 | |
| SRP064894 | UBE2O | 63893 | RNAseq | 0.6654 | 0.0003 | |
| SRP133303 | UBE2O | 63893 | RNAseq | 0.7780 | 0.0018 | |
| SRP159526 | UBE2O | 63893 | RNAseq | 0.9717 | 0.0001 | |
| SRP193095 | UBE2O | 63893 | RNAseq | 0.6729 | 0.0000 | |
| SRP219564 | UBE2O | 63893 | RNAseq | 0.3616 | 0.2051 | |
| TCGA | UBE2O | 63893 | RNAseq | 0.1194 | 0.0130 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by UBE2O expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2O:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2O | 63893 | 7 | 2 | 21 | |
| GSE20123 | UBE2O | 63893 | 7 | 2 | 21 | |
| GSE43470 | UBE2O | 63893 | 5 | 3 | 35 | |
| GSE46452 | UBE2O | 63893 | 34 | 0 | 25 | |
| GSE47630 | UBE2O | 63893 | 8 | 1 | 31 | |
| GSE54993 | UBE2O | 63893 | 2 | 5 | 63 | |
| GSE54994 | UBE2O | 63893 | 10 | 4 | 39 | |
| GSE60625 | UBE2O | 63893 | 6 | 0 | 5 | |
| GSE74703 | UBE2O | 63893 | 5 | 1 | 30 | |
| GSE74704 | UBE2O | 63893 | 5 | 1 | 14 | |
| TCGA | UBE2O | 63893 | 31 | 10 | 55 |
Total number of gains: 120; Total number of losses: 29; Total Number of normals: 339.
Somatic mutations of UBE2O:
Generating mutation plots.
Highly correlated genes for UBE2O:
Showing top 20/1115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2O | LRRC58 | 0.855035 | 3 | 0 | 3 |
| UBE2O | ZNRD1 | 0.796158 | 3 | 0 | 3 |
| UBE2O | WDTC1 | 0.7929 | 3 | 0 | 3 |
| UBE2O | GSK3A | 0.789101 | 3 | 0 | 3 |
| UBE2O | SSBP4 | 0.783062 | 3 | 0 | 3 |
| UBE2O | DHX33 | 0.781194 | 4 | 0 | 4 |
| UBE2O | SCAF4 | 0.781055 | 3 | 0 | 3 |
| UBE2O | DMAP1 | 0.776989 | 3 | 0 | 3 |
| UBE2O | TNFSF14 | 0.761354 | 3 | 0 | 3 |
| UBE2O | NACC1 | 0.755176 | 4 | 0 | 4 |
| UBE2O | ADAM22 | 0.754709 | 3 | 0 | 3 |
| UBE2O | TMEM63B | 0.753492 | 3 | 0 | 3 |
| UBE2O | GPR132 | 0.749774 | 3 | 0 | 3 |
| UBE2O | ZNF76 | 0.741214 | 3 | 0 | 3 |
| UBE2O | USF2 | 0.735895 | 4 | 0 | 3 |
| UBE2O | HPS3 | 0.729077 | 3 | 0 | 3 |
| UBE2O | ZNF707 | 0.727514 | 3 | 0 | 3 |
| UBE2O | DTX4 | 0.722735 | 3 | 0 | 3 |
| UBE2O | CXCL16 | 0.721434 | 3 | 0 | 3 |
| UBE2O | CCDC124 | 0.720721 | 3 | 0 | 3 |
For details and further investigation, click here
