| Full name: F-box and leucine rich repeat protein 7 | Alias Symbol: KIAA0840|FBL7|FBL6 | ||
| Type: protein-coding gene | Cytoband: 5p15.1 | ||
| Entrez ID: 23194 | HGNC ID: HGNC:13604 | Ensembl Gene: ENSG00000183580 | OMIM ID: 605656 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXL7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXL7 | 23194 | 213249_at | -1.4761 | 0.1162 | |
| GSE20347 | FBXL7 | 23194 | 213249_at | -0.3124 | 0.0079 | |
| GSE23400 | FBXL7 | 23194 | 213249_at | -0.3744 | 0.0000 | |
| GSE26886 | FBXL7 | 23194 | 213249_at | 0.3239 | 0.4640 | |
| GSE29001 | FBXL7 | 23194 | 213249_at | -0.7177 | 0.0326 | |
| GSE38129 | FBXL7 | 23194 | 213249_at | -0.6601 | 0.0038 | |
| GSE45670 | FBXL7 | 23194 | 213249_at | -2.1110 | 0.0000 | |
| GSE53622 | FBXL7 | 23194 | 30947 | -0.5784 | 0.0000 | |
| GSE53624 | FBXL7 | 23194 | 61223 | -0.7234 | 0.0000 | |
| GSE63941 | FBXL7 | 23194 | 213249_at | -3.9642 | 0.0000 | |
| GSE77861 | FBXL7 | 23194 | 213249_at | -0.1800 | 0.2022 | |
| GSE97050 | FBXL7 | 23194 | A_24_P7600 | -0.5804 | 0.1921 | |
| SRP007169 | FBXL7 | 23194 | RNAseq | 1.0296 | 0.0979 | |
| SRP064894 | FBXL7 | 23194 | RNAseq | -0.3557 | 0.2693 | |
| SRP133303 | FBXL7 | 23194 | RNAseq | -0.6404 | 0.0169 | |
| SRP159526 | FBXL7 | 23194 | RNAseq | -0.8814 | 0.0451 | |
| SRP193095 | FBXL7 | 23194 | RNAseq | 0.3100 | 0.2085 | |
| SRP219564 | FBXL7 | 23194 | RNAseq | -0.2872 | 0.6982 | |
| TCGA | FBXL7 | 23194 | RNAseq | -0.4197 | 0.0051 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FBXL7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXL7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXL7 | 23194 | 12 | 0 | 18 | |
| GSE20123 | FBXL7 | 23194 | 12 | 0 | 18 | |
| GSE43470 | FBXL7 | 23194 | 16 | 0 | 27 | |
| GSE46452 | FBXL7 | 23194 | 6 | 22 | 31 | |
| GSE47630 | FBXL7 | 23194 | 6 | 11 | 23 | |
| GSE54993 | FBXL7 | 23194 | 5 | 5 | 60 | |
| GSE54994 | FBXL7 | 23194 | 29 | 2 | 22 | |
| GSE60625 | FBXL7 | 23194 | 0 | 0 | 11 | |
| GSE74703 | FBXL7 | 23194 | 13 | 0 | 23 | |
| GSE74704 | FBXL7 | 23194 | 11 | 0 | 9 | |
| TCGA | FBXL7 | 23194 | 59 | 3 | 34 |
Total number of gains: 169; Total number of losses: 43; Total Number of normals: 276.
Somatic mutations of FBXL7:
Generating mutation plots.
Highly correlated genes for FBXL7:
Showing top 20/1068 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXL7 | MIR100HG | 0.838191 | 5 | 0 | 5 |
| FBXL7 | MAGI2-AS3 | 0.827159 | 6 | 0 | 6 |
| FBXL7 | NEGR1 | 0.819801 | 6 | 0 | 6 |
| FBXL7 | MRVI1 | 0.801142 | 6 | 0 | 6 |
| FBXL7 | ZFPM2 | 0.781902 | 9 | 0 | 9 |
| FBXL7 | PABPC5 | 0.773934 | 5 | 0 | 5 |
| FBXL7 | SMIM10 | 0.772634 | 5 | 0 | 5 |
| FBXL7 | CREBRF | 0.764021 | 3 | 0 | 3 |
| FBXL7 | LINC01082 | 0.762505 | 5 | 0 | 5 |
| FBXL7 | MYOCD | 0.761445 | 7 | 0 | 6 |
| FBXL7 | ARHGAP31 | 0.761189 | 5 | 0 | 5 |
| FBXL7 | ABCA6 | 0.760742 | 8 | 0 | 8 |
| FBXL7 | TCEAL7 | 0.759736 | 6 | 0 | 6 |
| FBXL7 | ARHGAP6 | 0.759454 | 11 | 0 | 9 |
| FBXL7 | RUNX1T1 | 0.758126 | 7 | 0 | 6 |
| FBXL7 | SCN7A | 0.757337 | 8 | 0 | 8 |
| FBXL7 | FXYD1 | 0.755559 | 7 | 0 | 7 |
| FBXL7 | FGF7 | 0.755223 | 7 | 0 | 7 |
| FBXL7 | BHMT2 | 0.755127 | 9 | 0 | 8 |
| FBXL7 | PREX2 | 0.753483 | 3 | 0 | 3 |
For details and further investigation, click here
