| Full name: ATP binding cassette subfamily A member 6 | Alias Symbol: EST155051 | ||
| Type: protein-coding gene | Cytoband: 17q24.2-q24.3 | ||
| Entrez ID: 23460 | HGNC ID: HGNC:36 | Ensembl Gene: ENSG00000154262 | OMIM ID: 612504 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCA6 | 23460 | 217504_at | -1.7367 | 0.1078 | |
| GSE20347 | ABCA6 | 23460 | 217504_at | -0.0891 | 0.1986 | |
| GSE23400 | ABCA6 | 23460 | 217504_at | -0.2022 | 0.0000 | |
| GSE26886 | ABCA6 | 23460 | 217504_at | -0.0568 | 0.6943 | |
| GSE29001 | ABCA6 | 23460 | 217504_at | -0.3006 | 0.0946 | |
| GSE38129 | ABCA6 | 23460 | 217504_at | -0.6537 | 0.0016 | |
| GSE45670 | ABCA6 | 23460 | 217504_at | -2.6831 | 0.0000 | |
| GSE53622 | ABCA6 | 23460 | 28583 | -1.3849 | 0.0000 | |
| GSE53624 | ABCA6 | 23460 | 28583 | -1.5903 | 0.0000 | |
| GSE63941 | ABCA6 | 23460 | 217504_at | -3.1193 | 0.0000 | |
| GSE77861 | ABCA6 | 23460 | 217504_at | 0.0654 | 0.4834 | |
| GSE97050 | ABCA6 | 23460 | A_23_P500400 | -0.6855 | 0.1276 | |
| SRP007169 | ABCA6 | 23460 | RNAseq | -0.2712 | 0.6671 | |
| SRP064894 | ABCA6 | 23460 | RNAseq | -0.7505 | 0.0950 | |
| SRP133303 | ABCA6 | 23460 | RNAseq | -1.2953 | 0.0051 | |
| SRP159526 | ABCA6 | 23460 | RNAseq | -1.1587 | 0.0714 | |
| SRP193095 | ABCA6 | 23460 | RNAseq | -0.5529 | 0.0569 | |
| SRP219564 | ABCA6 | 23460 | RNAseq | -0.5257 | 0.4146 | |
| TCGA | ABCA6 | 23460 | RNAseq | -1.2892 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ABCA6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCA6 | 23460 | 3 | 1 | 26 | |
| GSE20123 | ABCA6 | 23460 | 3 | 1 | 26 | |
| GSE43470 | ABCA6 | 23460 | 6 | 0 | 37 | |
| GSE46452 | ABCA6 | 23460 | 31 | 1 | 27 | |
| GSE47630 | ABCA6 | 23460 | 7 | 1 | 32 | |
| GSE54993 | ABCA6 | 23460 | 2 | 5 | 63 | |
| GSE54994 | ABCA6 | 23460 | 9 | 4 | 40 | |
| GSE60625 | ABCA6 | 23460 | 4 | 3 | 4 | |
| GSE74703 | ABCA6 | 23460 | 6 | 0 | 30 | |
| GSE74704 | ABCA6 | 23460 | 3 | 1 | 16 | |
| TCGA | ABCA6 | 23460 | 30 | 10 | 56 |
Total number of gains: 104; Total number of losses: 27; Total Number of normals: 357.
Somatic mutations of ABCA6:
Generating mutation plots.
Highly correlated genes for ABCA6:
Showing top 20/1248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCA6 | LRRN4CL | 0.867618 | 6 | 0 | 6 |
| ABCA6 | ANGPTL1 | 0.850288 | 6 | 0 | 6 |
| ABCA6 | NEGR1 | 0.84568 | 6 | 0 | 6 |
| ABCA6 | XKR4 | 0.84495 | 5 | 0 | 5 |
| ABCA6 | SHISA3 | 0.844237 | 5 | 0 | 5 |
| ABCA6 | CYP21A2 | 0.836025 | 3 | 0 | 3 |
| ABCA6 | MAGI2-AS3 | 0.835474 | 5 | 0 | 5 |
| ABCA6 | CLEC3B | 0.830752 | 3 | 0 | 3 |
| ABCA6 | MRVI1 | 0.829413 | 6 | 0 | 6 |
| ABCA6 | FIBIN | 0.828502 | 4 | 0 | 4 |
| ABCA6 | AFF3 | 0.813738 | 4 | 0 | 4 |
| ABCA6 | ADAMTS9-AS2 | 0.812876 | 5 | 0 | 5 |
| ABCA6 | PLCXD3 | 0.808925 | 4 | 0 | 4 |
| ABCA6 | PARD3B | 0.801567 | 5 | 0 | 5 |
| ABCA6 | UBXN10 | 0.800721 | 3 | 0 | 3 |
| ABCA6 | KCNT2 | 0.796136 | 6 | 0 | 6 |
| ABCA6 | MIR100HG | 0.794854 | 5 | 0 | 5 |
| ABCA6 | LYVE1 | 0.794757 | 8 | 0 | 8 |
| ABCA6 | RGS7BP | 0.790161 | 5 | 0 | 5 |
| ABCA6 | MYOCD | 0.787955 | 6 | 0 | 6 |
For details and further investigation, click here
