| Full name: fibroblast growth factor 7 | Alias Symbol: KGF | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 2252 | HGNC ID: HGNC:3685 | Ensembl Gene: ENSG00000140285 | OMIM ID: 148180 |
| Drug and gene relationship at DGIdb | |||
FGF7 involved pathways:
Expression of FGF7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGF7 | 2252 | 205782_at | -1.7566 | 0.0859 | |
| GSE20347 | FGF7 | 2252 | 205782_at | 0.0537 | 0.5580 | |
| GSE23400 | FGF7 | 2252 | 205782_at | -0.1710 | 0.0020 | |
| GSE26886 | FGF7 | 2252 | 205782_at | -0.0432 | 0.6688 | |
| GSE29001 | FGF7 | 2252 | 205782_at | -0.0192 | 0.9256 | |
| GSE38129 | FGF7 | 2252 | 205782_at | -0.7479 | 0.0925 | |
| GSE45670 | FGF7 | 2252 | 205782_at | -2.6937 | 0.0000 | |
| GSE53622 | FGF7 | 2252 | 39848 | -0.7113 | 0.0000 | |
| GSE53624 | FGF7 | 2252 | 39848 | -0.7326 | 0.0000 | |
| GSE63941 | FGF7 | 2252 | 205782_at | -7.5464 | 0.0000 | |
| GSE77861 | FGF7 | 2252 | 1555103_s_at | 0.0255 | 0.7398 | |
| GSE97050 | FGF7 | 2252 | A_33_P3257027 | 0.1827 | 0.4690 | |
| SRP007169 | FGF7 | 2252 | RNAseq | 1.9365 | 0.0003 | |
| SRP008496 | FGF7 | 2252 | RNAseq | 3.2473 | 0.0000 | |
| SRP064894 | FGF7 | 2252 | RNAseq | 0.3420 | 0.5138 | |
| SRP133303 | FGF7 | 2252 | RNAseq | -0.7481 | 0.0598 | |
| SRP159526 | FGF7 | 2252 | RNAseq | 0.8073 | 0.1753 | |
| SRP193095 | FGF7 | 2252 | RNAseq | 1.3252 | 0.0021 | |
| SRP219564 | FGF7 | 2252 | RNAseq | 0.6995 | 0.4369 | |
| TCGA | FGF7 | 2252 | RNAseq | -0.6945 | 0.0021 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by FGF7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGF7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGF7 | 2252 | 5 | 3 | 22 | |
| GSE20123 | FGF7 | 2252 | 5 | 3 | 22 | |
| GSE43470 | FGF7 | 2252 | 5 | 4 | 34 | |
| GSE46452 | FGF7 | 2252 | 3 | 7 | 49 | |
| GSE47630 | FGF7 | 2252 | 8 | 10 | 22 | |
| GSE54993 | FGF7 | 2252 | 4 | 6 | 60 | |
| GSE54994 | FGF7 | 2252 | 5 | 7 | 41 | |
| GSE60625 | FGF7 | 2252 | 4 | 0 | 7 | |
| GSE74703 | FGF7 | 2252 | 5 | 3 | 28 | |
| GSE74704 | FGF7 | 2252 | 2 | 3 | 15 | |
| TCGA | FGF7 | 2252 | 9 | 16 | 71 |
Total number of gains: 55; Total number of losses: 62; Total Number of normals: 371.
Somatic mutations of FGF7:
Generating mutation plots.
Highly correlated genes for FGF7:
Showing top 20/1286 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGF7 | AFF3 | 0.908985 | 3 | 0 | 3 |
| FGF7 | PGM5-AS1 | 0.891384 | 3 | 0 | 3 |
| FGF7 | FIBIN | 0.871483 | 4 | 0 | 4 |
| FGF7 | PEG3 | 0.822179 | 6 | 0 | 6 |
| FGF7 | C11orf96 | 0.812509 | 4 | 0 | 4 |
| FGF7 | LRRN4CL | 0.812483 | 6 | 0 | 6 |
| FGF7 | CYP4V2 | 0.810017 | 4 | 0 | 4 |
| FGF7 | SMIM10 | 0.809357 | 5 | 0 | 5 |
| FGF7 | ZBTB47 | 0.807035 | 3 | 0 | 3 |
| FGF7 | MSRB3 | 0.801011 | 6 | 0 | 6 |
| FGF7 | PDE1A | 0.797304 | 8 | 0 | 8 |
| FGF7 | MRGPRF | 0.797231 | 6 | 0 | 6 |
| FGF7 | FENDRR | 0.795983 | 5 | 0 | 5 |
| FGF7 | ZNF347 | 0.79376 | 3 | 0 | 3 |
| FGF7 | MRVI1 | 0.792669 | 6 | 0 | 5 |
| FGF7 | SLC16A4 | 0.791675 | 9 | 0 | 9 |
| FGF7 | APOB | 0.791635 | 3 | 0 | 3 |
| FGF7 | GNG11 | 0.787521 | 8 | 0 | 8 |
| FGF7 | LTBP1 | 0.784509 | 3 | 0 | 3 |
| FGF7 | DCHS1 | 0.783658 | 6 | 0 | 6 |
For details and further investigation, click here
