| Full name: Rho GTPase activating protein 31 | Alias Symbol: CDGAP | ||
| Type: protein-coding gene | Cytoband: 3q13.32-q13.33 | ||
| Entrez ID: 57514 | HGNC ID: HGNC:29216 | Ensembl Gene: ENSG00000031081 | OMIM ID: 610911 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP31 | 57514 | 226056_at | -0.5505 | 0.2312 | |
| GSE26886 | ARHGAP31 | 57514 | 226056_at | -0.1567 | 0.4259 | |
| GSE45670 | ARHGAP31 | 57514 | 226056_at | -0.8184 | 0.0000 | |
| GSE53622 | ARHGAP31 | 57514 | 28979 | -0.3213 | 0.0004 | |
| GSE53624 | ARHGAP31 | 57514 | 28979 | -0.6440 | 0.0000 | |
| GSE63941 | ARHGAP31 | 57514 | 226056_at | -1.4641 | 0.0014 | |
| GSE77861 | ARHGAP31 | 57514 | 226056_at | -0.0443 | 0.8215 | |
| GSE97050 | ARHGAP31 | 57514 | A_24_P349039 | 0.0055 | 0.9830 | |
| SRP007169 | ARHGAP31 | 57514 | RNAseq | -0.0550 | 0.9043 | |
| SRP008496 | ARHGAP31 | 57514 | RNAseq | 0.3523 | 0.2816 | |
| SRP064894 | ARHGAP31 | 57514 | RNAseq | 0.1359 | 0.5924 | |
| SRP133303 | ARHGAP31 | 57514 | RNAseq | -0.3799 | 0.0398 | |
| SRP159526 | ARHGAP31 | 57514 | RNAseq | -0.0631 | 0.8650 | |
| SRP193095 | ARHGAP31 | 57514 | RNAseq | 0.2174 | 0.1333 | |
| SRP219564 | ARHGAP31 | 57514 | RNAseq | -0.3544 | 0.4578 | |
| TCGA | ARHGAP31 | 57514 | RNAseq | -0.2649 | 0.0064 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ARHGAP31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP31 | 57514 | 17 | 0 | 13 | |
| GSE20123 | ARHGAP31 | 57514 | 17 | 0 | 13 | |
| GSE43470 | ARHGAP31 | 57514 | 21 | 1 | 21 | |
| GSE46452 | ARHGAP31 | 57514 | 14 | 5 | 40 | |
| GSE47630 | ARHGAP31 | 57514 | 16 | 5 | 19 | |
| GSE54993 | ARHGAP31 | 57514 | 2 | 6 | 62 | |
| GSE54994 | ARHGAP31 | 57514 | 30 | 4 | 19 | |
| GSE60625 | ARHGAP31 | 57514 | 0 | 6 | 5 | |
| GSE74703 | ARHGAP31 | 57514 | 17 | 1 | 18 | |
| GSE74704 | ARHGAP31 | 57514 | 13 | 0 | 7 | |
| TCGA | ARHGAP31 | 57514 | 53 | 7 | 36 |
Total number of gains: 200; Total number of losses: 35; Total Number of normals: 253.
Somatic mutations of ARHGAP31:
Generating mutation plots.
Highly correlated genes for ARHGAP31:
Showing top 20/968 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP31 | LINC01279 | 0.836194 | 3 | 0 | 3 |
| ARHGAP31 | TRIM8 | 0.825391 | 3 | 0 | 3 |
| ARHGAP31 | FIBIN | 0.80123 | 4 | 0 | 4 |
| ARHGAP31 | KDM5D | 0.80106 | 3 | 0 | 3 |
| ARHGAP31 | ZNF583 | 0.80003 | 3 | 0 | 3 |
| ARHGAP31 | TK2 | 0.793532 | 3 | 0 | 3 |
| ARHGAP31 | AFF3 | 0.791429 | 3 | 0 | 3 |
| ARHGAP31 | HABP4 | 0.790688 | 3 | 0 | 3 |
| ARHGAP31 | USP9Y | 0.789316 | 3 | 0 | 3 |
| ARHGAP31 | CNN1 | 0.787559 | 4 | 0 | 4 |
| ARHGAP31 | SMPD1 | 0.782811 | 4 | 0 | 3 |
| ARHGAP31 | UBE2R2 | 0.777075 | 3 | 0 | 3 |
| ARHGAP31 | CYP4V2 | 0.775747 | 4 | 0 | 4 |
| ARHGAP31 | MRC2 | 0.771288 | 3 | 0 | 3 |
| ARHGAP31 | TNFSF12 | 0.770285 | 3 | 0 | 3 |
| ARHGAP31 | LRRC17 | 0.767852 | 3 | 0 | 3 |
| ARHGAP31 | HINT3 | 0.767426 | 3 | 0 | 3 |
| ARHGAP31 | SCUBE3 | 0.766842 | 3 | 0 | 3 |
| ARHGAP31 | SLC16A4 | 0.765763 | 6 | 0 | 6 |
| ARHGAP31 | ARHGEF6 | 0.763108 | 6 | 0 | 5 |
For details and further investigation, click here
