| Full name: leucine rich repeat neuronal 4 | Alias Symbol: dJ1056H1.1|NLRR4 | ||
| Type: protein-coding gene | Cytoband: 20p12.3 | ||
| Entrez ID: 164312 | HGNC ID: HGNC:16208 | Ensembl Gene: ENSG00000125872 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRN4 | 164312 | 1553169_at | -0.0679 | 0.7728 | |
| GSE26886 | LRRN4 | 164312 | 1553169_at | 0.3806 | 0.0069 | |
| GSE45670 | LRRN4 | 164312 | 1553169_at | 0.1369 | 0.2692 | |
| GSE53622 | LRRN4 | 164312 | 21074 | -0.0557 | 0.4996 | |
| GSE53624 | LRRN4 | 164312 | 21074 | 0.0632 | 0.3454 | |
| GSE63941 | LRRN4 | 164312 | 1553169_at | -0.1878 | 0.2749 | |
| GSE77861 | LRRN4 | 164312 | 1553169_at | 0.0241 | 0.8630 | |
| GSE97050 | LRRN4 | 164312 | A_23_P351913 | 0.0124 | 0.9649 | |
| SRP133303 | LRRN4 | 164312 | RNAseq | -0.0518 | 0.8867 | |
| TCGA | LRRN4 | 164312 | RNAseq | 0.6541 | 0.1444 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRN4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRN4 | 164312 | 11 | 2 | 17 | |
| GSE20123 | LRRN4 | 164312 | 11 | 2 | 17 | |
| GSE43470 | LRRN4 | 164312 | 12 | 1 | 30 | |
| GSE46452 | LRRN4 | 164312 | 26 | 1 | 32 | |
| GSE47630 | LRRN4 | 164312 | 18 | 4 | 18 | |
| GSE54993 | LRRN4 | 164312 | 1 | 14 | 55 | |
| GSE54994 | LRRN4 | 164312 | 25 | 2 | 26 | |
| GSE60625 | LRRN4 | 164312 | 0 | 0 | 11 | |
| GSE74703 | LRRN4 | 164312 | 9 | 1 | 26 | |
| GSE74704 | LRRN4 | 164312 | 5 | 1 | 14 | |
| TCGA | LRRN4 | 164312 | 40 | 11 | 45 |
Total number of gains: 158; Total number of losses: 39; Total Number of normals: 291.
Somatic mutations of LRRN4:
Generating mutation plots.
Highly correlated genes for LRRN4:
Showing top 20/176 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRN4 | DOK7 | 0.733494 | 4 | 0 | 4 |
| LRRN4 | SCN1B | 0.720808 | 3 | 0 | 3 |
| LRRN4 | LIM2 | 0.719245 | 3 | 0 | 3 |
| LRRN4 | FGF17 | 0.711254 | 3 | 0 | 3 |
| LRRN4 | ASRGL1 | 0.703206 | 3 | 0 | 3 |
| LRRN4 | CADM4 | 0.700867 | 3 | 0 | 3 |
| LRRN4 | SHC3 | 0.694623 | 3 | 0 | 3 |
| LRRN4 | SP7 | 0.689669 | 3 | 0 | 3 |
| LRRN4 | ZNF697 | 0.688926 | 3 | 0 | 3 |
| LRRN4 | SLC22A12 | 0.683707 | 3 | 0 | 3 |
| LRRN4 | ZNF821 | 0.682927 | 3 | 0 | 3 |
| LRRN4 | PAX6 | 0.677908 | 3 | 0 | 3 |
| LRRN4 | HCRTR1 | 0.677625 | 4 | 0 | 4 |
| LRRN4 | RASL10A | 0.674265 | 3 | 0 | 3 |
| LRRN4 | SNED1 | 0.672843 | 4 | 0 | 4 |
| LRRN4 | GPHA2 | 0.671592 | 3 | 0 | 3 |
| LRRN4 | CCDC8 | 0.670842 | 3 | 0 | 3 |
| LRRN4 | GRIK4 | 0.66756 | 3 | 0 | 3 |
| LRRN4 | ANO7 | 0.667503 | 4 | 0 | 4 |
| LRRN4 | TLR6 | 0.659002 | 3 | 0 | 3 |
For details and further investigation, click here
