| Full name: dermcidin | Alias Symbol: AIDD|PIF|DSEP|HCAP|DCD-1 | ||
| Type: protein-coding gene | Cytoband: 12q13.2 | ||
| Entrez ID: 117159 | HGNC ID: HGNC:14669 | Ensembl Gene: ENSG00000161634 | OMIM ID: 606634 |
| Drug and gene relationship at DGIdb | |||
Expression of DCD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCD | 117159 | 1553946_at | -0.0110 | 0.9828 | |
| GSE26886 | DCD | 117159 | 1553946_at | -0.1705 | 0.2529 | |
| GSE45670 | DCD | 117159 | 1553946_at | -0.0132 | 0.9071 | |
| GSE53622 | DCD | 117159 | 3105 | -1.3799 | 0.0000 | |
| GSE53624 | DCD | 117159 | 6163 | -1.7072 | 0.0000 | |
| GSE63941 | DCD | 117159 | 1553946_at | 0.1642 | 0.3539 | |
| GSE77861 | DCD | 117159 | 1553946_at | -0.0824 | 0.4071 | |
| GSE97050 | DCD | 117159 | A_23_P76218 | -0.1850 | 0.5511 | |
| SRP133303 | DCD | 117159 | RNAseq | -0.9956 | 0.0025 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by DCD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCD | 117159 | 4 | 1 | 25 | |
| GSE20123 | DCD | 117159 | 4 | 1 | 25 | |
| GSE43470 | DCD | 117159 | 5 | 0 | 38 | |
| GSE46452 | DCD | 117159 | 7 | 1 | 51 | |
| GSE47630 | DCD | 117159 | 10 | 2 | 28 | |
| GSE54993 | DCD | 117159 | 0 | 5 | 65 | |
| GSE54994 | DCD | 117159 | 4 | 1 | 48 | |
| GSE60625 | DCD | 117159 | 0 | 0 | 11 | |
| GSE74703 | DCD | 117159 | 4 | 0 | 32 | |
| GSE74704 | DCD | 117159 | 3 | 1 | 16 | |
| TCGA | DCD | 117159 | 16 | 11 | 69 |
Total number of gains: 57; Total number of losses: 23; Total Number of normals: 408.
Somatic mutations of DCD:
Generating mutation plots.
Highly correlated genes for DCD:
Showing top 20/552 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCD | CLEC18C | 0.89137 | 3 | 0 | 3 |
| DCD | MAFG | 0.879555 | 3 | 0 | 3 |
| DCD | NOTO | 0.875772 | 3 | 0 | 3 |
| DCD | BARHL2 | 0.874094 | 3 | 0 | 3 |
| DCD | RNF222 | 0.84928 | 3 | 0 | 3 |
| DCD | TRH | 0.832328 | 3 | 0 | 3 |
| DCD | MFSD2B | 0.83161 | 3 | 0 | 3 |
| DCD | FAM163B | 0.830529 | 3 | 0 | 3 |
| DCD | KRTAP20-1 | 0.819077 | 3 | 0 | 3 |
| DCD | PCDH1 | 0.814003 | 3 | 0 | 3 |
| DCD | CLEC12B | 0.80634 | 3 | 0 | 3 |
| DCD | OR2Z1 | 0.802614 | 3 | 0 | 3 |
| DCD | KCNK7 | 0.783091 | 3 | 0 | 3 |
| DCD | CD164L2 | 0.775734 | 3 | 0 | 3 |
| DCD | KPRP | 0.77363 | 3 | 0 | 3 |
| DCD | C8G | 0.767253 | 3 | 0 | 3 |
| DCD | OTOP3 | 0.765744 | 3 | 0 | 3 |
| DCD | VMO1 | 0.765629 | 3 | 0 | 3 |
| DCD | TEN1 | 0.764943 | 3 | 0 | 3 |
| DCD | FGF17 | 0.759569 | 3 | 0 | 3 |
For details and further investigation, click here
