| Full name: immunoglobulin like and fibronectin type III domain containing 1 | Alias Symbol: DKFZp434B1231|EEF1A2BP1 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 91156 | HGNC ID: HGNC:24607 | Ensembl Gene: ENSG00000163395 | OMIM ID: 617309 |
| Drug and gene relationship at DGIdb | |||
Expression of IGFN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGFN1 | 91156 | 1563098_at | 0.1021 | 0.7061 | |
| GSE26886 | IGFN1 | 91156 | 229275_at | 0.2924 | 0.1755 | |
| GSE45670 | IGFN1 | 91156 | 229275_at | 0.2515 | 0.2218 | |
| GSE53622 | IGFN1 | 91156 | 71760 | -0.3617 | 0.0005 | |
| GSE53624 | IGFN1 | 91156 | 71760 | -0.5918 | 0.0000 | |
| GSE63941 | IGFN1 | 91156 | 229275_at | 0.0257 | 0.8577 | |
| GSE77861 | IGFN1 | 91156 | 229275_at | -0.1151 | 0.3716 | |
| GSE97050 | IGFN1 | 91156 | A_33_P3382100 | -0.2627 | 0.2316 | |
| TCGA | IGFN1 | 91156 | RNAseq | 1.7793 | 0.0264 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IGFN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGFN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGFN1 | 91156 | 12 | 0 | 18 | |
| GSE20123 | IGFN1 | 91156 | 12 | 0 | 18 | |
| GSE43470 | IGFN1 | 91156 | 6 | 0 | 37 | |
| GSE46452 | IGFN1 | 91156 | 3 | 1 | 55 | |
| GSE47630 | IGFN1 | 91156 | 14 | 0 | 26 | |
| GSE54993 | IGFN1 | 91156 | 0 | 6 | 64 | |
| GSE54994 | IGFN1 | 91156 | 15 | 0 | 38 | |
| GSE60625 | IGFN1 | 91156 | 0 | 0 | 11 | |
| GSE74703 | IGFN1 | 91156 | 6 | 0 | 30 | |
| GSE74704 | IGFN1 | 91156 | 5 | 0 | 15 | |
| TCGA | IGFN1 | 91156 | 43 | 4 | 49 |
Total number of gains: 116; Total number of losses: 11; Total Number of normals: 361.
Somatic mutations of IGFN1:
Generating mutation plots.
Highly correlated genes for IGFN1:
Showing top 20/228 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGFN1 | HOXD9 | 0.842429 | 3 | 0 | 3 |
| IGFN1 | KCNT1 | 0.839089 | 3 | 0 | 3 |
| IGFN1 | ISLR2 | 0.814422 | 3 | 0 | 3 |
| IGFN1 | ZMYND10 | 0.812554 | 3 | 0 | 3 |
| IGFN1 | FAM71A | 0.812188 | 3 | 0 | 3 |
| IGFN1 | FOXB1 | 0.804934 | 3 | 0 | 3 |
| IGFN1 | SLC25A47 | 0.795689 | 3 | 0 | 3 |
| IGFN1 | PKLR | 0.792987 | 3 | 0 | 3 |
| IGFN1 | SHANK1 | 0.788942 | 3 | 0 | 3 |
| IGFN1 | CABP1 | 0.788776 | 3 | 0 | 3 |
| IGFN1 | CPNE7 | 0.756888 | 3 | 0 | 3 |
| IGFN1 | MAP3K10 | 0.753083 | 4 | 0 | 4 |
| IGFN1 | SCARF2 | 0.752415 | 3 | 0 | 3 |
| IGFN1 | TMEM52 | 0.751005 | 3 | 0 | 3 |
| IGFN1 | OR10G8 | 0.746626 | 3 | 0 | 3 |
| IGFN1 | SP8 | 0.746263 | 3 | 0 | 3 |
| IGFN1 | CCDC114 | 0.745912 | 4 | 0 | 4 |
| IGFN1 | CELF4 | 0.743417 | 3 | 0 | 3 |
| IGFN1 | ISYNA1 | 0.733856 | 3 | 0 | 3 |
| IGFN1 | FGF17 | 0.730977 | 4 | 0 | 3 |
For details and further investigation, click here
