| Full name: proteasome subunit beta 11 | Alias Symbol: beta5t | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 122706 | HGNC ID: HGNC:31963 | Ensembl Gene: ENSG00000222028 | OMIM ID: 611137 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PSMB11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | PSMB11 | 122706 | 17772 | 0.4424 | 0.0000 | |
| GSE53624 | PSMB11 | 122706 | 17772 | 0.5123 | 0.0000 | |
| GSE97050 | PSMB11 | 122706 | A_33_P3229375 | 0.0050 | 0.9848 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMB11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMB11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMB11 | 122706 | 9 | 2 | 19 | |
| GSE20123 | PSMB11 | 122706 | 9 | 2 | 19 | |
| GSE43470 | PSMB11 | 122706 | 7 | 2 | 34 | |
| GSE46452 | PSMB11 | 122706 | 17 | 2 | 40 | |
| GSE47630 | PSMB11 | 122706 | 11 | 10 | 19 | |
| GSE54993 | PSMB11 | 122706 | 3 | 11 | 56 | |
| GSE54994 | PSMB11 | 122706 | 18 | 5 | 30 | |
| GSE60625 | PSMB11 | 122706 | 0 | 2 | 9 | |
| GSE74703 | PSMB11 | 122706 | 6 | 2 | 28 | |
| GSE74704 | PSMB11 | 122706 | 4 | 1 | 15 | |
| TCGA | PSMB11 | 122706 | 27 | 15 | 54 |
Total number of gains: 111; Total number of losses: 54; Total Number of normals: 323.
Somatic mutations of PSMB11:
Generating mutation plots.
Highly correlated genes for PSMB11:
Showing top 20/100 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMB11 | ST8SIA1 | 0.82134 | 3 | 0 | 3 |
| PSMB11 | GPR182 | 0.820853 | 3 | 0 | 3 |
| PSMB11 | MEGF11 | 0.797883 | 3 | 0 | 3 |
| PSMB11 | SNED1 | 0.796894 | 3 | 0 | 3 |
| PSMB11 | TMEM179 | 0.796321 | 3 | 0 | 3 |
| PSMB11 | SLC6A3 | 0.787053 | 3 | 0 | 3 |
| PSMB11 | CIB3 | 0.778589 | 3 | 0 | 3 |
| PSMB11 | ST8SIA3 | 0.7767 | 3 | 0 | 3 |
| PSMB11 | CPNE7 | 0.770629 | 3 | 0 | 3 |
| PSMB11 | ZNF236 | 0.768777 | 3 | 0 | 3 |
| PSMB11 | NKX6-3 | 0.76792 | 3 | 0 | 3 |
| PSMB11 | GPR32 | 0.764581 | 3 | 0 | 3 |
| PSMB11 | CRYGC | 0.763516 | 3 | 0 | 3 |
| PSMB11 | TAZ | 0.761776 | 3 | 0 | 3 |
| PSMB11 | SYT1 | 0.76111 | 3 | 0 | 3 |
| PSMB11 | PDE6C | 0.761056 | 3 | 0 | 3 |
| PSMB11 | MS4A18 | 0.76013 | 3 | 0 | 3 |
| PSMB11 | GPHA2 | 0.759515 | 3 | 0 | 3 |
| PSMB11 | RBM43 | 0.75463 | 3 | 0 | 3 |
| PSMB11 | CBX8 | 0.753737 | 3 | 0 | 3 |
For details and further investigation, click here
