| Full name: ADP ribosylation factor like GTPase 4D | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 379 | HGNC ID: HGNC:656 | Ensembl Gene: ENSG00000175906 | OMIM ID: 600732 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL4D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL4D | 379 | 203586_s_at | -0.9924 | 0.2089 | |
| GSE20347 | ARL4D | 379 | 203586_s_at | -1.0326 | 0.0000 | |
| GSE23400 | ARL4D | 379 | 203586_s_at | -0.4671 | 0.0000 | |
| GSE26886 | ARL4D | 379 | 203586_s_at | -0.7301 | 0.0116 | |
| GSE29001 | ARL4D | 379 | 203586_s_at | -0.9455 | 0.0005 | |
| GSE38129 | ARL4D | 379 | 203586_s_at | -0.6982 | 0.0001 | |
| GSE45670 | ARL4D | 379 | 203586_s_at | -0.1198 | 0.6898 | |
| GSE53622 | ARL4D | 379 | 22718 | -0.4843 | 0.0000 | |
| GSE53624 | ARL4D | 379 | 22718 | -0.8192 | 0.0000 | |
| GSE63941 | ARL4D | 379 | 203586_s_at | 0.6969 | 0.1681 | |
| GSE77861 | ARL4D | 379 | 203586_s_at | -0.2481 | 0.2803 | |
| GSE97050 | ARL4D | 379 | A_33_P3392525 | -0.7052 | 0.2151 | |
| SRP007169 | ARL4D | 379 | RNAseq | -0.4066 | 0.4772 | |
| SRP064894 | ARL4D | 379 | RNAseq | -1.0047 | 0.0001 | |
| SRP133303 | ARL4D | 379 | RNAseq | -0.9043 | 0.0195 | |
| SRP159526 | ARL4D | 379 | RNAseq | -1.8248 | 0.0001 | |
| SRP219564 | ARL4D | 379 | RNAseq | -1.5100 | 0.0064 | |
| TCGA | ARL4D | 379 | RNAseq | 0.5902 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ARL4D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL4D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL4D | 379 | 6 | 2 | 22 | |
| GSE20123 | ARL4D | 379 | 6 | 2 | 22 | |
| GSE43470 | ARL4D | 379 | 1 | 2 | 40 | |
| GSE46452 | ARL4D | 379 | 34 | 0 | 25 | |
| GSE47630 | ARL4D | 379 | 8 | 1 | 31 | |
| GSE54993 | ARL4D | 379 | 3 | 4 | 63 | |
| GSE54994 | ARL4D | 379 | 8 | 5 | 40 | |
| GSE60625 | ARL4D | 379 | 4 | 0 | 7 | |
| GSE74703 | ARL4D | 379 | 1 | 1 | 34 | |
| GSE74704 | ARL4D | 379 | 3 | 1 | 16 | |
| TCGA | ARL4D | 379 | 22 | 7 | 67 |
Total number of gains: 96; Total number of losses: 25; Total Number of normals: 367.
Somatic mutations of ARL4D:
Generating mutation plots.
Highly correlated genes for ARL4D:
Showing top 20/576 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL4D | FFAR2 | 0.777065 | 3 | 0 | 3 |
| ARL4D | FGF17 | 0.722475 | 3 | 0 | 3 |
| ARL4D | AQP4 | 0.716663 | 3 | 0 | 3 |
| ARL4D | CRYGA | 0.716019 | 3 | 0 | 3 |
| ARL4D | TP73 | 0.713034 | 3 | 0 | 3 |
| ARL4D | OR3A3 | 0.707039 | 3 | 0 | 3 |
| ARL4D | HMGB4 | 0.690115 | 3 | 0 | 3 |
| ARL4D | MFSD2B | 0.686688 | 3 | 0 | 3 |
| ARL4D | TGM1 | 0.686408 | 9 | 0 | 9 |
| ARL4D | CLIC3 | 0.685466 | 7 | 0 | 7 |
| ARL4D | ASB10 | 0.683279 | 3 | 0 | 3 |
| ARL4D | PTK6 | 0.681251 | 11 | 0 | 10 |
| ARL4D | SERPINB1 | 0.680321 | 9 | 0 | 9 |
| ARL4D | BARHL2 | 0.677604 | 3 | 0 | 3 |
| ARL4D | C22orf23 | 0.676712 | 3 | 0 | 3 |
| ARL4D | DSG1 | 0.676484 | 5 | 0 | 4 |
| ARL4D | OR2Z1 | 0.668179 | 3 | 0 | 3 |
| ARL4D | RXFP3 | 0.66803 | 7 | 0 | 6 |
| ARL4D | CES2 | 0.664594 | 8 | 0 | 8 |
| ARL4D | CYSRT1 | 0.662131 | 5 | 0 | 5 |
For details and further investigation, click here
