| Full name: fascin actin-bundling protein 2, retinal | Alias Symbol: RP30|RFSN | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 25794 | HGNC ID: HGNC:3960 | Ensembl Gene: ENSG00000186765 | OMIM ID: 607643 |
| Drug and gene relationship at DGIdb | |||
Expression of FSCN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FSCN2 | 25794 | 207204_at | -0.0713 | 0.7789 | |
| GSE20347 | FSCN2 | 25794 | 207204_at | -0.0567 | 0.3600 | |
| GSE23400 | FSCN2 | 25794 | 207204_at | -0.0545 | 0.0060 | |
| GSE26886 | FSCN2 | 25794 | 207204_at | 0.1944 | 0.2108 | |
| GSE29001 | FSCN2 | 25794 | 207204_at | -0.0181 | 0.9066 | |
| GSE38129 | FSCN2 | 25794 | 207204_at | -0.0895 | 0.1078 | |
| GSE45670 | FSCN2 | 25794 | 207204_at | -0.0278 | 0.7868 | |
| GSE53622 | FSCN2 | 25794 | 64519 | -0.0458 | 0.6174 | |
| GSE53624 | FSCN2 | 25794 | 64519 | -0.0944 | 0.2279 | |
| GSE63941 | FSCN2 | 25794 | 207204_at | 0.0665 | 0.7078 | |
| GSE77861 | FSCN2 | 25794 | 207204_at | -0.0746 | 0.5964 | |
| GSE97050 | FSCN2 | 25794 | A_33_P3411080 | 0.1326 | 0.5323 | |
| SRP133303 | FSCN2 | 25794 | RNAseq | -0.1947 | 0.5140 | |
| SRP219564 | FSCN2 | 25794 | RNAseq | -0.1415 | 0.7670 | |
| TCGA | FSCN2 | 25794 | RNAseq | -1.0182 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FSCN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FSCN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FSCN2 | 25794 | 4 | 4 | 22 | |
| GSE20123 | FSCN2 | 25794 | 4 | 4 | 22 | |
| GSE43470 | FSCN2 | 25794 | 3 | 5 | 35 | |
| GSE46452 | FSCN2 | 25794 | 34 | 0 | 25 | |
| GSE47630 | FSCN2 | 25794 | 9 | 2 | 29 | |
| GSE54993 | FSCN2 | 25794 | 2 | 5 | 63 | |
| GSE54994 | FSCN2 | 25794 | 10 | 6 | 37 | |
| GSE60625 | FSCN2 | 25794 | 6 | 0 | 5 | |
| GSE74703 | FSCN2 | 25794 | 3 | 3 | 30 | |
| GSE74704 | FSCN2 | 25794 | 4 | 3 | 13 | |
| TCGA | FSCN2 | 25794 | 25 | 12 | 59 |
Total number of gains: 104; Total number of losses: 44; Total Number of normals: 340.
Somatic mutations of FSCN2:
Generating mutation plots.
Highly correlated genes for FSCN2:
Showing top 20/471 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FSCN2 | CLEC18C | 0.793332 | 3 | 0 | 3 |
| FSCN2 | CCL27 | 0.754936 | 4 | 0 | 4 |
| FSCN2 | MRGPRE | 0.744592 | 3 | 0 | 3 |
| FSCN2 | KCNAB3 | 0.732457 | 4 | 0 | 4 |
| FSCN2 | TSGA10 | 0.726016 | 3 | 0 | 3 |
| FSCN2 | PRR18 | 0.722409 | 3 | 0 | 3 |
| FSCN2 | MYLK3 | 0.714227 | 3 | 0 | 3 |
| FSCN2 | ACSBG2 | 0.707515 | 3 | 0 | 3 |
| FSCN2 | TUBA3D | 0.706185 | 3 | 0 | 3 |
| FSCN2 | C1QTNF6 | 0.70164 | 3 | 0 | 3 |
| FSCN2 | KRTAP6-1 | 0.700292 | 3 | 0 | 3 |
| FSCN2 | RUFY4 | 0.698131 | 3 | 0 | 3 |
| FSCN2 | SSX5 | 0.696196 | 3 | 0 | 3 |
| FSCN2 | HBM | 0.695643 | 4 | 0 | 4 |
| FSCN2 | TRIM31 | 0.695196 | 4 | 0 | 3 |
| FSCN2 | G6PC2 | 0.695009 | 3 | 0 | 3 |
| FSCN2 | PKDREJ | 0.689984 | 3 | 0 | 3 |
| FSCN2 | CALCR | 0.688218 | 4 | 0 | 4 |
| FSCN2 | MGAT5B | 0.688139 | 5 | 0 | 5 |
| FSCN2 | NOTO | 0.68688 | 3 | 0 | 3 |
For details and further investigation, click here
