| Full name: RUN and FYVE domain containing 4 | Alias Symbol: FLJ46536|ZFYVE31 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 285180 | HGNC ID: HGNC:24804 | Ensembl Gene: ENSG00000188282 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RUFY4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | RUFY4 | 285180 | 49317 | -0.1901 | 0.2937 | |
| GSE53624 | RUFY4 | 285180 | 49317 | -0.2321 | 0.0894 | |
| GSE97050 | RUFY4 | 285180 | A_33_P3296997 | 0.0254 | 0.9481 | |
| SRP133303 | RUFY4 | 285180 | RNAseq | 0.1976 | 0.6144 | |
| SRP159526 | RUFY4 | 285180 | RNAseq | -0.5880 | 0.3836 | |
| SRP219564 | RUFY4 | 285180 | RNAseq | 0.6410 | 0.4678 | |
| TCGA | RUFY4 | 285180 | RNAseq | 1.7590 | 0.0008 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RUFY4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RUFY4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RUFY4 | 285180 | 1 | 13 | 16 | |
| GSE20123 | RUFY4 | 285180 | 1 | 13 | 16 | |
| GSE43470 | RUFY4 | 285180 | 1 | 7 | 35 | |
| GSE46452 | RUFY4 | 285180 | 0 | 5 | 54 | |
| GSE47630 | RUFY4 | 285180 | 4 | 5 | 31 | |
| GSE54993 | RUFY4 | 285180 | 0 | 3 | 67 | |
| GSE54994 | RUFY4 | 285180 | 8 | 10 | 35 | |
| GSE60625 | RUFY4 | 285180 | 0 | 3 | 8 | |
| GSE74703 | RUFY4 | 285180 | 1 | 5 | 30 | |
| GSE74704 | RUFY4 | 285180 | 1 | 7 | 12 | |
| TCGA | RUFY4 | 285180 | 11 | 27 | 58 |
Total number of gains: 28; Total number of losses: 98; Total Number of normals: 362.
Somatic mutations of RUFY4:
Generating mutation plots.
Highly correlated genes for RUFY4:
Showing top 20/30 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RUFY4 | MGAT5B | 0.735908 | 3 | 0 | 3 |
| RUFY4 | RHBDL1 | 0.725475 | 3 | 0 | 3 |
| RUFY4 | PHOSPHO1 | 0.715145 | 3 | 0 | 3 |
| RUFY4 | PLA2G4F | 0.714642 | 3 | 0 | 3 |
| RUFY4 | BEST3 | 0.706551 | 3 | 0 | 3 |
| RUFY4 | NKX2-3 | 0.705459 | 3 | 0 | 3 |
| RUFY4 | GPHB5 | 0.699285 | 3 | 0 | 3 |
| RUFY4 | EFNA3 | 0.69825 | 3 | 0 | 3 |
| RUFY4 | FSCN2 | 0.698131 | 3 | 0 | 3 |
| RUFY4 | PLCH2 | 0.695697 | 3 | 0 | 3 |
| RUFY4 | TFAP2E | 0.693339 | 3 | 0 | 3 |
| RUFY4 | RAD51D | 0.681574 | 3 | 0 | 3 |
| RUFY4 | FAM120C | 0.671677 | 3 | 0 | 3 |
| RUFY4 | GHRHR | 0.662306 | 4 | 0 | 3 |
| RUFY4 | KCNA7 | 0.66095 | 3 | 0 | 3 |
| RUFY4 | TSHB | 0.658914 | 3 | 0 | 3 |
| RUFY4 | TCTEX1D4 | 0.657516 | 3 | 0 | 3 |
| RUFY4 | SLC4A9 | 0.651108 | 3 | 0 | 3 |
| RUFY4 | AGER | 0.650112 | 3 | 0 | 3 |
| RUFY4 | TAS2R14 | 0.649583 | 3 | 0 | 3 |
For details and further investigation, click here
