| Full name: tubulin alpha 3d | Alias Symbol: H2-ALPHA | ||
| Type: protein-coding gene | Cytoband: 2q21.1 | ||
| Entrez ID: 113457 | HGNC ID: HGNC:24071 | Ensembl Gene: ENSG00000075886 | OMIM ID: 617878 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
TUBA3D involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04210 | Apoptosis | |
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBA3D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TUBA3D | 113457 | 106619 | 0.0306 | 0.6941 | |
| GSE53624 | TUBA3D | 113457 | 106619 | 0.0013 | 0.9905 | |
| GSE97050 | TUBA3D | 113457 | A_23_P56736 | 0.0714 | 0.7222 | |
| SRP133303 | TUBA3D | 113457 | RNAseq | -0.3824 | 0.1424 | |
| SRP159526 | TUBA3D | 113457 | RNAseq | -0.2135 | 0.6962 | |
| TCGA | TUBA3D | 113457 | RNAseq | -0.0770 | 0.7944 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TUBA3D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TUBA3D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBA3D | 113457 | 4 | 3 | 23 | |
| GSE20123 | TUBA3D | 113457 | 4 | 3 | 23 | |
| GSE43470 | TUBA3D | 113457 | 2 | 2 | 39 | |
| GSE46452 | TUBA3D | 113457 | 1 | 4 | 54 | |
| GSE47630 | TUBA3D | 113457 | 5 | 0 | 35 | |
| GSE54993 | TUBA3D | 113457 | 0 | 6 | 64 | |
| GSE54994 | TUBA3D | 113457 | 10 | 0 | 43 | |
| GSE60625 | TUBA3D | 113457 | 0 | 3 | 8 | |
| GSE74703 | TUBA3D | 113457 | 2 | 1 | 33 | |
| GSE74704 | TUBA3D | 113457 | 2 | 1 | 17 | |
| TCGA | TUBA3D | 113457 | 22 | 9 | 65 |
Total number of gains: 52; Total number of losses: 32; Total Number of normals: 404.
Somatic mutations of TUBA3D:
Generating mutation plots.
Highly correlated genes for TUBA3D:
Showing top 20/147 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBA3D | SLC22A31 | 0.798164 | 3 | 0 | 3 |
| TUBA3D | CELF5 | 0.797807 | 3 | 0 | 3 |
| TUBA3D | GRIK4 | 0.786693 | 3 | 0 | 3 |
| TUBA3D | KCP | 0.77707 | 3 | 0 | 3 |
| TUBA3D | KCNH3 | 0.774948 | 3 | 0 | 3 |
| TUBA3D | SPACA3 | 0.774005 | 3 | 0 | 3 |
| TUBA3D | CLDN9 | 0.771847 | 3 | 0 | 3 |
| TUBA3D | FBRSL1 | 0.767836 | 3 | 0 | 3 |
| TUBA3D | GH1 | 0.765541 | 3 | 0 | 3 |
| TUBA3D | RNF180 | 0.760438 | 3 | 0 | 3 |
| TUBA3D | WDR87 | 0.759464 | 3 | 0 | 3 |
| TUBA3D | BTNL2 | 0.758051 | 3 | 0 | 3 |
| TUBA3D | CNOT3 | 0.757858 | 3 | 0 | 3 |
| TUBA3D | TRIM10 | 0.754399 | 3 | 0 | 3 |
| TUBA3D | CIB3 | 0.753768 | 3 | 0 | 3 |
| TUBA3D | SLC22A25 | 0.752763 | 3 | 0 | 3 |
| TUBA3D | PTAFR | 0.752135 | 3 | 0 | 3 |
| TUBA3D | SLC18A3 | 0.748798 | 3 | 0 | 3 |
| TUBA3D | KRTAP4-8 | 0.748603 | 3 | 0 | 3 |
| TUBA3D | SLC22A8 | 0.748073 | 3 | 0 | 3 |
For details and further investigation, click here
