| Full name: potassium voltage-gated channel subfamily A regulatory beta subunit 3 | Alias Symbol: AKR6A9|KCNA3B | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 9196 | HGNC ID: HGNC:6230 | Ensembl Gene: ENSG00000170049 | OMIM ID: 604111 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNAB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNAB3 | 9196 | 221413_at | -0.1160 | 0.6321 | |
| GSE20347 | KCNAB3 | 9196 | 221413_at | 0.0883 | 0.3312 | |
| GSE23400 | KCNAB3 | 9196 | 221413_at | -0.1012 | 0.0081 | |
| GSE26886 | KCNAB3 | 9196 | 221413_at | 0.2203 | 0.0623 | |
| GSE29001 | KCNAB3 | 9196 | 221413_at | -0.0554 | 0.7507 | |
| GSE38129 | KCNAB3 | 9196 | 221413_at | -0.0789 | 0.4281 | |
| GSE45670 | KCNAB3 | 9196 | 221413_at | 0.0297 | 0.7751 | |
| GSE63941 | KCNAB3 | 9196 | 221413_at | -0.0013 | 0.9942 | |
| GSE77861 | KCNAB3 | 9196 | 221413_at | -0.1318 | 0.2389 | |
| GSE97050 | KCNAB3 | 9196 | A_23_P370454 | 0.1786 | 0.4211 | |
| SRP064894 | KCNAB3 | 9196 | RNAseq | 1.5591 | 0.0000 | |
| SRP133303 | KCNAB3 | 9196 | RNAseq | 0.3581 | 0.1312 | |
| SRP219564 | KCNAB3 | 9196 | RNAseq | 0.7442 | 0.2448 | |
| TCGA | KCNAB3 | 9196 | RNAseq | 0.5532 | 0.0510 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KCNAB3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KCNAB3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNAB3 | 9196 | 4 | 2 | 24 | |
| GSE20123 | KCNAB3 | 9196 | 4 | 3 | 23 | |
| GSE43470 | KCNAB3 | 9196 | 1 | 6 | 36 | |
| GSE46452 | KCNAB3 | 9196 | 34 | 1 | 24 | |
| GSE47630 | KCNAB3 | 9196 | 7 | 1 | 32 | |
| GSE54993 | KCNAB3 | 9196 | 4 | 3 | 63 | |
| GSE54994 | KCNAB3 | 9196 | 5 | 8 | 40 | |
| GSE60625 | KCNAB3 | 9196 | 4 | 0 | 7 | |
| GSE74703 | KCNAB3 | 9196 | 1 | 3 | 32 | |
| GSE74704 | KCNAB3 | 9196 | 2 | 1 | 17 | |
| TCGA | KCNAB3 | 9196 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of KCNAB3:
Generating mutation plots.
Highly correlated genes for KCNAB3:
Showing top 20/830 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNAB3 | OR10C1 | 0.73981 | 5 | 0 | 5 |
| KCNAB3 | ORM1 | 0.734273 | 3 | 0 | 3 |
| KCNAB3 | ATG16L1 | 0.734069 | 3 | 0 | 3 |
| KCNAB3 | COLEC10 | 0.732517 | 5 | 0 | 5 |
| KCNAB3 | FSCN2 | 0.732457 | 4 | 0 | 4 |
| KCNAB3 | IFNA4 | 0.726932 | 6 | 0 | 6 |
| KCNAB3 | PLA2G2D | 0.722747 | 4 | 0 | 3 |
| KCNAB3 | FOLH1 | 0.722164 | 5 | 0 | 5 |
| KCNAB3 | KIR3DL3 | 0.71812 | 5 | 0 | 5 |
| KCNAB3 | DNAH2 | 0.709859 | 3 | 0 | 3 |
| KCNAB3 | SCGN | 0.709148 | 4 | 0 | 4 |
| KCNAB3 | CHIT1 | 0.705524 | 3 | 0 | 3 |
| KCNAB3 | MAGEA8 | 0.704787 | 3 | 0 | 3 |
| KCNAB3 | FAM131A | 0.704002 | 3 | 0 | 3 |
| KCNAB3 | SHROOM1 | 0.700502 | 4 | 0 | 4 |
| KCNAB3 | FASLG | 0.699214 | 6 | 0 | 5 |
| KCNAB3 | HAUS5 | 0.696301 | 4 | 0 | 4 |
| KCNAB3 | KLK3 | 0.696232 | 4 | 0 | 4 |
| KCNAB3 | TMEM184A | 0.696225 | 3 | 0 | 3 |
| KCNAB3 | PRAMEF12 | 0.691741 | 5 | 0 | 5 |
For details and further investigation, click here
