| Full name: DnaJ heat shock protein family (Hsp40) member B8 | Alias Symbol: MGC33884|CT156 | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 165721 | HGNC ID: HGNC:23699 | Ensembl Gene: ENSG00000179407 | OMIM ID: 611337 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJB8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJB8 | 165721 | 237284_at | -0.0136 | 0.9537 | |
| GSE26886 | DNAJB8 | 165721 | 237284_at | 0.2345 | 0.0523 | |
| GSE45670 | DNAJB8 | 165721 | 237284_at | -0.0947 | 0.2736 | |
| GSE53622 | DNAJB8 | 165721 | 58642 | -0.2338 | 0.0389 | |
| GSE53624 | DNAJB8 | 165721 | 58642 | -0.5948 | 0.0000 | |
| GSE63941 | DNAJB8 | 165721 | 237284_at | 0.0571 | 0.7223 | |
| GSE77861 | DNAJB8 | 165721 | 237284_at | -0.0536 | 0.6827 | |
| GSE97050 | DNAJB8 | 165721 | A_23_P121413 | -0.2178 | 0.4304 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAJB8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJB8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJB8 | 165721 | 17 | 0 | 13 | |
| GSE20123 | DNAJB8 | 165721 | 17 | 0 | 13 | |
| GSE43470 | DNAJB8 | 165721 | 19 | 0 | 24 | |
| GSE46452 | DNAJB8 | 165721 | 14 | 5 | 40 | |
| GSE47630 | DNAJB8 | 165721 | 18 | 3 | 19 | |
| GSE54993 | DNAJB8 | 165721 | 2 | 7 | 61 | |
| GSE54994 | DNAJB8 | 165721 | 31 | 3 | 19 | |
| GSE60625 | DNAJB8 | 165721 | 0 | 6 | 5 | |
| GSE74703 | DNAJB8 | 165721 | 17 | 0 | 19 | |
| GSE74704 | DNAJB8 | 165721 | 13 | 0 | 7 | |
| TCGA | DNAJB8 | 165721 | 58 | 5 | 33 |
Total number of gains: 206; Total number of losses: 29; Total Number of normals: 253.
Somatic mutations of DNAJB8:
Generating mutation plots.
Highly correlated genes for DNAJB8:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJB8 | ARHGAP30 | 0.787968 | 3 | 0 | 3 |
| DNAJB8 | QRICH2 | 0.786085 | 3 | 0 | 3 |
| DNAJB8 | KRTAP10-8 | 0.775301 | 3 | 0 | 3 |
| DNAJB8 | PPP1R12C | 0.77087 | 3 | 0 | 3 |
| DNAJB8 | FUZ | 0.765297 | 3 | 0 | 3 |
| DNAJB8 | MIIP | 0.75421 | 3 | 0 | 3 |
| DNAJB8 | TDGF1 | 0.752652 | 3 | 0 | 3 |
| DNAJB8 | PRDM16 | 0.751208 | 3 | 0 | 3 |
| DNAJB8 | KRTAP6-1 | 0.747846 | 3 | 0 | 3 |
| DNAJB8 | PICK1 | 0.742392 | 3 | 0 | 3 |
| DNAJB8 | TM6SF2 | 0.742378 | 3 | 0 | 3 |
| DNAJB8 | GRAP | 0.735177 | 3 | 0 | 3 |
| DNAJB8 | CAPN10 | 0.734105 | 3 | 0 | 3 |
| DNAJB8 | DUOXA2 | 0.731903 | 3 | 0 | 3 |
| DNAJB8 | SHANK1 | 0.729566 | 3 | 0 | 3 |
| DNAJB8 | UQCRC1 | 0.72699 | 3 | 0 | 3 |
| DNAJB8 | GPD1 | 0.724795 | 3 | 0 | 3 |
| DNAJB8 | HTR3A | 0.721877 | 3 | 0 | 3 |
| DNAJB8 | ZIC1 | 0.719815 | 3 | 0 | 3 |
| DNAJB8 | TRIM17 | 0.719804 | 3 | 0 | 3 |
For details and further investigation, click here
