GPR39

 

Full name: G protein-coupled receptor 39 Alias Symbol: 
Type: protein-coding gene Cytoband: 2q21.2
Entrez ID: 2863 HGNC ID: HGNC:4496 Ensembl Gene: ENSG00000183840 OMIM ID: 602886
Drug and gene relationship at DGIdb

 

Expression of GPR39:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GPR39 2863 229104_s_at 0.2450 0.6196
GSE20347 GPR39 2863 208600_s_at 0.0442 0.4356
GSE23400 GPR39 2863 208600_s_at -0.0476 0.1224
GSE26886 GPR39 2863 229105_at 0.4631 0.4192
GSE29001 GPR39 2863 208600_s_at 0.0287 0.8276
GSE38129 GPR39 2863 208600_s_at 0.0400 0.4662
GSE45670 GPR39 2863 229104_s_at 0.3169 0.0135
GSE63941 GPR39 2863 229105_at 1.5417 0.1050
GSE77861 GPR39 2863 229104_s_at -0.0696 0.5607
GSE97050 GPR39 2863 A_23_P79155 0.3619 0.3339
SRP133303 GPR39 2863 RNAseq 1.2276 0.0124
SRP159526 GPR39 2863 RNAseq -0.4705 0.4998
SRP193095 GPR39 2863 RNAseq -0.2502 0.5694
SRP219564 GPR39 2863 RNAseq 1.9397 0.0595
TCGA GPR39 2863 RNAseq -0.5497 0.0826

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by GPR39 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of GPR39:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GPR39 2863 3 4 23
GSE20123 GPR39 2863 3 4 23
GSE43470 GPR39 2863 2 1 40
GSE46452 GPR39 2863 1 4 54
GSE47630 GPR39 2863 5 2 33
GSE54993 GPR39 2863 0 6 64
GSE54994 GPR39 2863 10 1 42
GSE60625 GPR39 2863 0 3 8
GSE74703 GPR39 2863 2 1 33
GSE74704 GPR39 2863 2 2 16
TCGA GPR39 2863 23 12 61

Total number of gains: 51; Total number of losses: 40; Total Number of normals: 397.  


 

Somatic mutations of GPR39:

 

Generating mutation plots.

 

Highly correlated genes for GPR39:

 

Showing top 20/331 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GPR39FUZ0.768681303
GPR39CNGB10.747817303
GPR39LIM20.744906403
GPR39CLCN20.740688303
GPR39MGAT5B0.737209303
GPR39CALCR0.735228303
GPR39LTB4R0.731813303
GPR39PCDH10.725562303
GPR39TTC7A0.720701404
GPR39TRIM310.719611404
GPR39C4BPA0.70751303
GPR39PPP1R3F0.707045404
GPR39CC2D1B0.700876303
GPR39PTGER10.698987404
GPR39ZNF5720.696631303
GPR39KIF170.691542303
GPR39C19orf810.689126303
GPR39ELMO30.688878303
GPR39ACSM2A0.687783303
GPR39IGSF210.683564303

For details and further investigation, click here