| Full name: leukocyte receptor cluster member 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 79165 | HGNC ID: HGNC:15502 | Ensembl Gene: ENSG00000105617 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LENG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LENG1 | 79165 | 232018_at | -0.0132 | 0.9698 | |
| GSE26886 | LENG1 | 79165 | 232018_at | 0.5334 | 0.0004 | |
| GSE45670 | LENG1 | 79165 | 232018_at | -0.0234 | 0.8523 | |
| GSE53622 | LENG1 | 79165 | 45867 | 0.0378 | 0.6321 | |
| GSE53624 | LENG1 | 79165 | 45867 | 0.1473 | 0.0718 | |
| GSE63941 | LENG1 | 79165 | 232018_at | -0.1427 | 0.6042 | |
| GSE77861 | LENG1 | 79165 | 232018_at | -0.1314 | 0.5330 | |
| GSE97050 | LENG1 | 79165 | A_23_P208523 | 0.0246 | 0.9371 | |
| SRP064894 | LENG1 | 79165 | RNAseq | 0.6225 | 0.0662 | |
| SRP133303 | LENG1 | 79165 | RNAseq | -0.0298 | 0.8685 | |
| SRP159526 | LENG1 | 79165 | RNAseq | 0.1765 | 0.5783 | |
| SRP193095 | LENG1 | 79165 | RNAseq | 0.2528 | 0.0575 | |
| SRP219564 | LENG1 | 79165 | RNAseq | 0.1378 | 0.6930 | |
| TCGA | LENG1 | 79165 | RNAseq | -0.0515 | 0.4821 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LENG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LENG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LENG1 | 79165 | 3 | 4 | 23 | |
| GSE20123 | LENG1 | 79165 | 3 | 3 | 24 | |
| GSE43470 | LENG1 | 79165 | 2 | 11 | 30 | |
| GSE46452 | LENG1 | 79165 | 45 | 1 | 13 | |
| GSE47630 | LENG1 | 79165 | 8 | 6 | 26 | |
| GSE54993 | LENG1 | 79165 | 17 | 4 | 49 | |
| GSE54994 | LENG1 | 79165 | 4 | 14 | 35 | |
| GSE60625 | LENG1 | 79165 | 9 | 0 | 2 | |
| GSE74703 | LENG1 | 79165 | 2 | 7 | 27 | |
| GSE74704 | LENG1 | 79165 | 3 | 1 | 16 | |
| TCGA | LENG1 | 79165 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 66; Total Number of normals: 307.
Somatic mutations of LENG1:
Generating mutation plots.
Highly correlated genes for LENG1:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LENG1 | NPEPL1 | 0.801835 | 3 | 0 | 3 |
| LENG1 | RANBP3 | 0.780136 | 3 | 0 | 3 |
| LENG1 | FUZ | 0.77762 | 3 | 0 | 3 |
| LENG1 | NKX2-8 | 0.762574 | 3 | 0 | 3 |
| LENG1 | TRIM31 | 0.75936 | 3 | 0 | 3 |
| LENG1 | AGAP2 | 0.751664 | 3 | 0 | 3 |
| LENG1 | SEMA3B | 0.74925 | 3 | 0 | 3 |
| LENG1 | KLHL26 | 0.746024 | 3 | 0 | 3 |
| LENG1 | CDH23 | 0.744763 | 3 | 0 | 3 |
| LENG1 | POLE4 | 0.744181 | 3 | 0 | 3 |
| LENG1 | GNL1 | 0.741918 | 3 | 0 | 3 |
| LENG1 | IGFALS | 0.741276 | 3 | 0 | 3 |
| LENG1 | ZNF444 | 0.738286 | 4 | 0 | 4 |
| LENG1 | CCNJL | 0.73719 | 3 | 0 | 3 |
| LENG1 | CDH4 | 0.736571 | 3 | 0 | 3 |
| LENG1 | ZCCHC18 | 0.730219 | 3 | 0 | 3 |
| LENG1 | SURF2 | 0.728349 | 3 | 0 | 3 |
| LENG1 | POLL | 0.727741 | 3 | 0 | 3 |
| LENG1 | TEF | 0.725747 | 3 | 0 | 3 |
| LENG1 | IGSF9B | 0.724446 | 3 | 0 | 3 |
For details and further investigation, click here
