| Full name: glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | Alias Symbol: GAPDH-2|GAPD2 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 26330 | HGNC ID: HGNC:24864 | Ensembl Gene: ENSG00000105679 | OMIM ID: 609169 |
| Drug and gene relationship at DGIdb | |||
Expression of GAPDHS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GAPDHS | 26330 | 207116_s_at | -0.1061 | 0.6244 | |
| GSE20347 | GAPDHS | 26330 | 207116_s_at | -0.0399 | 0.5933 | |
| GSE23400 | GAPDHS | 26330 | 207116_s_at | -0.1032 | 0.0052 | |
| GSE26886 | GAPDHS | 26330 | 207116_s_at | -0.1958 | 0.1866 | |
| GSE29001 | GAPDHS | 26330 | 207116_s_at | -0.1338 | 0.2440 | |
| GSE38129 | GAPDHS | 26330 | 207116_s_at | -0.0963 | 0.0755 | |
| GSE45670 | GAPDHS | 26330 | 207116_s_at | 0.0734 | 0.5526 | |
| GSE53622 | GAPDHS | 26330 | 8528 | -0.1290 | 0.2440 | |
| GSE53624 | GAPDHS | 26330 | 8528 | -0.1250 | 0.1996 | |
| GSE63941 | GAPDHS | 26330 | 207116_s_at | 0.1731 | 0.3044 | |
| GSE77861 | GAPDHS | 26330 | 207116_s_at | -0.1316 | 0.1309 | |
| SRP133303 | GAPDHS | 26330 | RNAseq | -0.3378 | 0.0375 | |
| SRP159526 | GAPDHS | 26330 | RNAseq | 1.0698 | 0.0026 | |
| SRP193095 | GAPDHS | 26330 | RNAseq | 0.4137 | 0.0030 | |
| SRP219564 | GAPDHS | 26330 | RNAseq | -0.5451 | 0.3644 | |
| TCGA | GAPDHS | 26330 | RNAseq | 1.8015 | 0.0018 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by GAPDHS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GAPDHS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GAPDHS | 26330 | 6 | 4 | 20 | |
| GSE20123 | GAPDHS | 26330 | 6 | 3 | 21 | |
| GSE43470 | GAPDHS | 26330 | 3 | 7 | 33 | |
| GSE46452 | GAPDHS | 26330 | 48 | 1 | 10 | |
| GSE47630 | GAPDHS | 26330 | 9 | 5 | 26 | |
| GSE54993 | GAPDHS | 26330 | 17 | 3 | 50 | |
| GSE54994 | GAPDHS | 26330 | 8 | 9 | 36 | |
| GSE60625 | GAPDHS | 26330 | 9 | 0 | 2 | |
| GSE74703 | GAPDHS | 26330 | 3 | 4 | 29 | |
| GSE74704 | GAPDHS | 26330 | 6 | 1 | 13 | |
| TCGA | GAPDHS | 26330 | 21 | 11 | 64 |
Total number of gains: 136; Total number of losses: 48; Total Number of normals: 304.
Somatic mutations of GAPDHS:
Generating mutation plots.
Highly correlated genes for GAPDHS:
Showing top 20/331 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GAPDHS | PITRM1-AS1 | 0.66329 | 4 | 0 | 4 |
| GAPDHS | LINC00347 | 0.66023 | 3 | 0 | 3 |
| GAPDHS | NLRP14 | 0.657201 | 3 | 0 | 3 |
| GAPDHS | MIR4755 | 0.642687 | 3 | 0 | 3 |
| GAPDHS | LRRC43 | 0.632719 | 3 | 0 | 3 |
| GAPDHS | ECEL1 | 0.62855 | 5 | 0 | 4 |
| GAPDHS | TTR | 0.627784 | 4 | 0 | 4 |
| GAPDHS | LINC00922 | 0.624433 | 3 | 0 | 3 |
| GAPDHS | ANKRD31 | 0.622947 | 3 | 0 | 3 |
| GAPDHS | TXNDC2 | 0.621576 | 3 | 0 | 3 |
| GAPDHS | UNC79 | 0.614476 | 4 | 0 | 4 |
| GAPDHS | LGALS13 | 0.613985 | 4 | 0 | 3 |
| GAPDHS | ZC4H2 | 0.613251 | 3 | 0 | 3 |
| GAPDHS | LINC01210 | 0.609637 | 4 | 0 | 3 |
| GAPDHS | PRL | 0.608222 | 5 | 0 | 5 |
| GAPDHS | KLK4 | 0.60687 | 4 | 0 | 4 |
| GAPDHS | HAND1 | 0.604226 | 4 | 0 | 4 |
| GAPDHS | ADARB2-AS1 | 0.598836 | 4 | 0 | 4 |
| GAPDHS | KCNIP1 | 0.59787 | 7 | 0 | 5 |
| GAPDHS | FAM71D | 0.596876 | 3 | 0 | 3 |
For details and further investigation, click here
