| Full name: NLR family pyrin domain containing 14 | Alias Symbol: NOD5|GC-LRR|Nalp-iota|PAN8|CLR11.2 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 338323 | HGNC ID: HGNC:22939 | Ensembl Gene: ENSG00000158077 | OMIM ID: 609665 |
| Drug and gene relationship at DGIdb | |||
Expression of NLRP14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NLRP14 | 338323 | 1553523_at | 0.0435 | 0.8683 | |
| GSE26886 | NLRP14 | 338323 | 1553523_at | -0.1791 | 0.1694 | |
| GSE45670 | NLRP14 | 338323 | 1553523_at | 0.1503 | 0.1717 | |
| GSE53622 | NLRP14 | 338323 | 20674 | -0.1224 | 0.1815 | |
| GSE53624 | NLRP14 | 338323 | 20674 | -0.4688 | 0.0000 | |
| GSE63941 | NLRP14 | 338323 | 1553523_at | 0.0089 | 0.9624 | |
| GSE77861 | NLRP14 | 338323 | 1553523_at | -0.1985 | 0.0388 | |
| TCGA | NLRP14 | 338323 | RNAseq | 0.6282 | 0.4169 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NLRP14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NLRP14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NLRP14 | 338323 | 0 | 11 | 19 | |
| GSE20123 | NLRP14 | 338323 | 0 | 11 | 19 | |
| GSE43470 | NLRP14 | 338323 | 1 | 8 | 34 | |
| GSE46452 | NLRP14 | 338323 | 7 | 8 | 44 | |
| GSE47630 | NLRP14 | 338323 | 2 | 12 | 26 | |
| GSE54993 | NLRP14 | 338323 | 3 | 1 | 66 | |
| GSE54994 | NLRP14 | 338323 | 2 | 12 | 39 | |
| GSE60625 | NLRP14 | 338323 | 0 | 0 | 11 | |
| GSE74703 | NLRP14 | 338323 | 1 | 6 | 29 | |
| GSE74704 | NLRP14 | 338323 | 0 | 8 | 12 | |
| TCGA | NLRP14 | 338323 | 9 | 37 | 50 |
Total number of gains: 25; Total number of losses: 114; Total Number of normals: 349.
Somatic mutations of NLRP14:
Generating mutation plots.
Highly correlated genes for NLRP14:
Showing all 14 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NLRP14 | OR2B2 | 0.667006 | 3 | 0 | 3 |
| NLRP14 | GAPDHS | 0.657201 | 3 | 0 | 3 |
| NLRP14 | LINC00330 | 0.606188 | 3 | 0 | 3 |
| NLRP14 | KLHL10 | 0.596367 | 3 | 0 | 3 |
| NLRP14 | ONECUT1 | 0.593618 | 4 | 0 | 3 |
| NLRP14 | PRKACG | 0.59053 | 3 | 0 | 3 |
| NLRP14 | F11 | 0.570182 | 3 | 0 | 3 |
| NLRP14 | FGF22 | 0.565774 | 3 | 0 | 3 |
| NLRP14 | LINC00880 | 0.56474 | 3 | 0 | 3 |
| NLRP14 | GBA3 | 0.562935 | 3 | 0 | 3 |
| NLRP14 | PSPN | 0.522342 | 5 | 0 | 3 |
| NLRP14 | GPR45 | 0.521092 | 5 | 0 | 4 |
| NLRP14 | ZNF135 | 0.517988 | 4 | 0 | 3 |
| NLRP14 | LINC01281 | 0.504229 | 4 | 0 | 3 |
For details and further investigation, click here
