| Full name: endothelin converting enzyme like 1 | Alias Symbol: XCE|DINE | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 9427 | HGNC ID: HGNC:3147 | Ensembl Gene: ENSG00000171551 | OMIM ID: 605896 |
| Drug and gene relationship at DGIdb | |||
Expression of ECEL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECEL1 | 9427 | 219914_at | -0.1699 | 0.3832 | |
| GSE20347 | ECEL1 | 9427 | 219914_at | -0.0631 | 0.4563 | |
| GSE23400 | ECEL1 | 9427 | 219914_at | -0.1155 | 0.0044 | |
| GSE26886 | ECEL1 | 9427 | 219914_at | 0.0403 | 0.8194 | |
| GSE29001 | ECEL1 | 9427 | 219914_at | -0.0113 | 0.9446 | |
| GSE38129 | ECEL1 | 9427 | 219914_at | -0.0800 | 0.3130 | |
| GSE45670 | ECEL1 | 9427 | 219914_at | 0.0487 | 0.6173 | |
| GSE53622 | ECEL1 | 9427 | 128613 | 0.3478 | 0.0407 | |
| GSE53624 | ECEL1 | 9427 | 128613 | 0.4457 | 0.0047 | |
| GSE63941 | ECEL1 | 9427 | 219914_at | 0.2038 | 0.5981 | |
| GSE77861 | ECEL1 | 9427 | 219914_at | -0.2279 | 0.0583 | |
| GSE97050 | ECEL1 | 9427 | A_32_P155666 | 0.4597 | 0.1628 | |
| SRP219564 | ECEL1 | 9427 | RNAseq | 4.2386 | 0.0001 | |
| TCGA | ECEL1 | 9427 | RNAseq | 0.8399 | 0.1354 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ECEL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ECEL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECEL1 | 9427 | 1 | 12 | 17 | |
| GSE20123 | ECEL1 | 9427 | 1 | 12 | 17 | |
| GSE43470 | ECEL1 | 9427 | 1 | 8 | 34 | |
| GSE46452 | ECEL1 | 9427 | 0 | 5 | 54 | |
| GSE47630 | ECEL1 | 9427 | 4 | 5 | 31 | |
| GSE54993 | ECEL1 | 9427 | 3 | 2 | 65 | |
| GSE54994 | ECEL1 | 9427 | 6 | 10 | 37 | |
| GSE60625 | ECEL1 | 9427 | 0 | 3 | 8 | |
| GSE74703 | ECEL1 | 9427 | 1 | 6 | 29 | |
| GSE74704 | ECEL1 | 9427 | 1 | 5 | 14 | |
| TCGA | ECEL1 | 9427 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 97; Total Number of normals: 362.
Somatic mutations of ECEL1:
Generating mutation plots.
Highly correlated genes for ECEL1:
Showing top 20/479 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECEL1 | SFTA2 | 0.739138 | 3 | 0 | 3 |
| ECEL1 | SLC2A5 | 0.696045 | 3 | 0 | 3 |
| ECEL1 | HLA-DQB2 | 0.693315 | 3 | 0 | 3 |
| ECEL1 | SLC25A35 | 0.689088 | 3 | 0 | 3 |
| ECEL1 | FANCA | 0.687813 | 3 | 0 | 3 |
| ECEL1 | WNK1 | 0.687485 | 3 | 0 | 3 |
| ECEL1 | PRELID1 | 0.681805 | 3 | 0 | 3 |
| ECEL1 | MAPK11 | 0.681578 | 4 | 0 | 4 |
| ECEL1 | OLFM2 | 0.673122 | 3 | 0 | 3 |
| ECEL1 | CGA | 0.672875 | 4 | 0 | 3 |
| ECEL1 | CHRNB1 | 0.666575 | 3 | 0 | 3 |
| ECEL1 | NTNG1 | 0.662575 | 3 | 0 | 3 |
| ECEL1 | CALCB | 0.661427 | 4 | 0 | 3 |
| ECEL1 | FSTL4 | 0.657887 | 4 | 0 | 3 |
| ECEL1 | CPA2 | 0.65758 | 3 | 0 | 3 |
| ECEL1 | GBP6 | 0.65415 | 3 | 0 | 3 |
| ECEL1 | TRIM50 | 0.652342 | 4 | 0 | 3 |
| ECEL1 | FIG4 | 0.651669 | 3 | 0 | 3 |
| ECEL1 | CHRNE | 0.645998 | 4 | 0 | 3 |
| ECEL1 | OR10J1 | 0.645436 | 4 | 0 | 4 |
For details and further investigation, click here
