| Full name: thioredoxin domain containing 2 | Alias Symbol: SPTRX1 | ||
| Type: protein-coding gene | Cytoband: 18p11.31-p11.2 | ||
| Entrez ID: 84203 | HGNC ID: HGNC:16470 | Ensembl Gene: ENSG00000168454 | OMIM ID: 617790 |
| Drug and gene relationship at DGIdb | |||
Expression of TXNDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TXNDC2 | 84203 | 1552657_a_at | -0.1074 | 0.7264 | |
| GSE26886 | TXNDC2 | 84203 | 1552657_a_at | -0.1067 | 0.5571 | |
| GSE45670 | TXNDC2 | 84203 | 1552657_a_at | 0.1629 | 0.0580 | |
| GSE53622 | TXNDC2 | 84203 | 34005 | 0.1121 | 0.1754 | |
| GSE53624 | TXNDC2 | 84203 | 34005 | 0.1594 | 0.0849 | |
| GSE63941 | TXNDC2 | 84203 | 1552657_a_at | 0.3937 | 0.0128 | |
| GSE77861 | TXNDC2 | 84203 | 1552657_a_at | -0.0872 | 0.3770 | |
| GSE97050 | TXNDC2 | 84203 | A_24_P125434 | -0.0282 | 0.9034 | |
| TCGA | TXNDC2 | 84203 | RNAseq | 0.9093 | 0.0490 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TXNDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TXNDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TXNDC2 | 84203 | 6 | 3 | 21 | |
| GSE20123 | TXNDC2 | 84203 | 6 | 3 | 21 | |
| GSE43470 | TXNDC2 | 84203 | 3 | 6 | 34 | |
| GSE46452 | TXNDC2 | 84203 | 3 | 21 | 35 | |
| GSE47630 | TXNDC2 | 84203 | 7 | 17 | 16 | |
| GSE54993 | TXNDC2 | 84203 | 6 | 2 | 62 | |
| GSE54994 | TXNDC2 | 84203 | 8 | 8 | 37 | |
| GSE60625 | TXNDC2 | 84203 | 0 | 4 | 7 | |
| GSE74703 | TXNDC2 | 84203 | 2 | 4 | 30 | |
| GSE74704 | TXNDC2 | 84203 | 4 | 2 | 14 | |
| TCGA | TXNDC2 | 84203 | 29 | 23 | 44 |
Total number of gains: 74; Total number of losses: 93; Total Number of normals: 321.
Somatic mutations of TXNDC2:
Generating mutation plots.
Highly correlated genes for TXNDC2:
Showing top 20/819 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TXNDC2 | PRSS38 | 0.889715 | 3 | 0 | 3 |
| TXNDC2 | BSX | 0.867461 | 3 | 0 | 3 |
| TXNDC2 | C1QL2 | 0.867146 | 3 | 0 | 3 |
| TXNDC2 | DCDC1 | 0.866197 | 3 | 0 | 3 |
| TXNDC2 | YY2 | 0.857197 | 3 | 0 | 3 |
| TXNDC2 | PABPN1L | 0.850839 | 3 | 0 | 3 |
| TXNDC2 | OR2T27 | 0.839348 | 3 | 0 | 3 |
| TXNDC2 | FOXA3 | 0.834316 | 3 | 0 | 3 |
| TXNDC2 | BBC3 | 0.832558 | 3 | 0 | 3 |
| TXNDC2 | OR2T1 | 0.823056 | 3 | 0 | 3 |
| TXNDC2 | C10orf91 | 0.816933 | 3 | 0 | 3 |
| TXNDC2 | MRGPRG | 0.816017 | 3 | 0 | 3 |
| TXNDC2 | SPACA3 | 0.815986 | 3 | 0 | 3 |
| TXNDC2 | OTOG | 0.814308 | 3 | 0 | 3 |
| TXNDC2 | TULP2 | 0.814079 | 3 | 0 | 3 |
| TXNDC2 | PDE6C | 0.809358 | 3 | 0 | 3 |
| TXNDC2 | OR2A5 | 0.808608 | 3 | 0 | 3 |
| TXNDC2 | CLTCL1 | 0.806169 | 4 | 0 | 4 |
| TXNDC2 | PLA2G2C | 0.804303 | 3 | 0 | 3 |
| TXNDC2 | OR2B11 | 0.8042 | 3 | 0 | 3 |
For details and further investigation, click here
