| Full name: GIPC PDZ domain containing family member 2 | Alias Symbol: FLJ20075|SEMCAP-2 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 54810 | HGNC ID: HGNC:18177 | Ensembl Gene: ENSG00000137960 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GIPC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GIPC2 | 54810 | 219970_at | -1.3880 | 0.1786 | |
| GSE20347 | GIPC2 | 54810 | 219970_at | -1.0787 | 0.0000 | |
| GSE23400 | GIPC2 | 54810 | 219970_at | -0.1765 | 0.0053 | |
| GSE26886 | GIPC2 | 54810 | 219970_at | -0.3189 | 0.5342 | |
| GSE29001 | GIPC2 | 54810 | 219970_at | -0.3376 | 0.5773 | |
| GSE38129 | GIPC2 | 54810 | 219970_at | -1.2894 | 0.0000 | |
| GSE45670 | GIPC2 | 54810 | 219970_at | -1.0744 | 0.0626 | |
| GSE63941 | GIPC2 | 54810 | 236548_at | 0.0450 | 0.9516 | |
| GSE77861 | GIPC2 | 54810 | 219970_at | -0.2136 | 0.6129 | |
| GSE97050 | GIPC2 | 54810 | A_33_P3390122 | -0.1126 | 0.8415 | |
| SRP007169 | GIPC2 | 54810 | RNAseq | -0.1287 | 0.8794 | |
| SRP064894 | GIPC2 | 54810 | RNAseq | -1.3120 | 0.0003 | |
| SRP133303 | GIPC2 | 54810 | RNAseq | -0.8634 | 0.1277 | |
| SRP159526 | GIPC2 | 54810 | RNAseq | -1.3614 | 0.0560 | |
| SRP193095 | GIPC2 | 54810 | RNAseq | -1.3194 | 0.0011 | |
| SRP219564 | GIPC2 | 54810 | RNAseq | -1.5072 | 0.0698 | |
| TCGA | GIPC2 | 54810 | RNAseq | -1.1278 | 0.0021 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by GIPC2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GIPC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GIPC2 | 54810 | 0 | 7 | 23 | |
| GSE20123 | GIPC2 | 54810 | 0 | 7 | 23 | |
| GSE43470 | GIPC2 | 54810 | 4 | 3 | 36 | |
| GSE46452 | GIPC2 | 54810 | 0 | 1 | 58 | |
| GSE47630 | GIPC2 | 54810 | 8 | 6 | 26 | |
| GSE54993 | GIPC2 | 54810 | 0 | 0 | 70 | |
| GSE54994 | GIPC2 | 54810 | 6 | 3 | 44 | |
| GSE60625 | GIPC2 | 54810 | 0 | 0 | 11 | |
| GSE74703 | GIPC2 | 54810 | 3 | 2 | 31 | |
| GSE74704 | GIPC2 | 54810 | 0 | 4 | 16 | |
| TCGA | GIPC2 | 54810 | 8 | 25 | 63 |
Total number of gains: 29; Total number of losses: 58; Total Number of normals: 401.
Somatic mutations of GIPC2:
Generating mutation plots.
Highly correlated genes for GIPC2:
Showing top 20/443 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GIPC2 | TMOD2 | 0.736359 | 3 | 0 | 3 |
| GIPC2 | HDHD2 | 0.724206 | 3 | 0 | 3 |
| GIPC2 | AK3 | 0.719558 | 3 | 0 | 3 |
| GIPC2 | FBXO8 | 0.713721 | 3 | 0 | 3 |
| GIPC2 | TMEM167B | 0.712556 | 3 | 0 | 3 |
| GIPC2 | KIAA1191 | 0.706343 | 3 | 0 | 3 |
| GIPC2 | LRRK2 | 0.699617 | 3 | 0 | 3 |
| GIPC2 | DENND4C | 0.696852 | 5 | 0 | 5 |
| GIPC2 | RABL3 | 0.696761 | 4 | 0 | 4 |
| GIPC2 | DCTN2 | 0.676052 | 4 | 0 | 4 |
| GIPC2 | ZNF662 | 0.672401 | 3 | 0 | 3 |
| GIPC2 | ACO1 | 0.670873 | 6 | 0 | 5 |
| GIPC2 | KIF13B | 0.670312 | 5 | 0 | 5 |
| GIPC2 | CRIP2 | 0.665552 | 4 | 0 | 4 |
| GIPC2 | HEMK1 | 0.665328 | 5 | 0 | 5 |
| GIPC2 | RHOJ | 0.66291 | 3 | 0 | 3 |
| GIPC2 | RNF183 | 0.661665 | 4 | 0 | 3 |
| GIPC2 | ZYG11B | 0.656446 | 4 | 0 | 3 |
| GIPC2 | CCNY | 0.656266 | 3 | 0 | 3 |
| GIPC2 | TBC1D20 | 0.655055 | 4 | 0 | 3 |
For details and further investigation, click here
