| Full name: cysteine rich protein 2 | Alias Symbol: CRP2|ESP1 | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 1397 | HGNC ID: HGNC:2361 | Ensembl Gene: ENSG00000182809 | OMIM ID: 601183 |
| Drug and gene relationship at DGIdb | |||
Expression of CRIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRIP2 | 1397 | 208978_at | -1.5143 | 0.0274 | |
| GSE20347 | CRIP2 | 1397 | 208978_at | -2.0257 | 0.0000 | |
| GSE23400 | CRIP2 | 1397 | 208978_at | -1.1712 | 0.0000 | |
| GSE26886 | CRIP2 | 1397 | 208978_at | -0.7640 | 0.0248 | |
| GSE29001 | CRIP2 | 1397 | 208978_at | -0.6456 | 0.0186 | |
| GSE38129 | CRIP2 | 1397 | 208978_at | -1.8367 | 0.0000 | |
| GSE45670 | CRIP2 | 1397 | 208978_at | -0.9893 | 0.0001 | |
| GSE53622 | CRIP2 | 1397 | 11508 | -1.2727 | 0.0000 | |
| GSE53624 | CRIP2 | 1397 | 11508 | -1.3579 | 0.0000 | |
| GSE63941 | CRIP2 | 1397 | 208978_at | 2.3422 | 0.0472 | |
| GSE77861 | CRIP2 | 1397 | 208978_at | -0.9232 | 0.0442 | |
| GSE97050 | CRIP2 | 1397 | A_23_P112798 | -0.1397 | 0.7658 | |
| SRP007169 | CRIP2 | 1397 | RNAseq | -1.7407 | 0.0145 | |
| SRP008496 | CRIP2 | 1397 | RNAseq | -1.4164 | 0.0125 | |
| SRP064894 | CRIP2 | 1397 | RNAseq | -0.2820 | 0.4218 | |
| SRP133303 | CRIP2 | 1397 | RNAseq | -0.8913 | 0.0002 | |
| SRP159526 | CRIP2 | 1397 | RNAseq | -1.4473 | 0.0000 | |
| SRP193095 | CRIP2 | 1397 | RNAseq | -0.5027 | 0.0289 | |
| SRP219564 | CRIP2 | 1397 | RNAseq | -0.3292 | 0.5946 | |
| TCGA | CRIP2 | 1397 | RNAseq | -0.1492 | 0.1125 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by CRIP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRIP2 | 1397 | 11 | 3 | 16 | |
| GSE20123 | CRIP2 | 1397 | 10 | 2 | 18 | |
| GSE43470 | CRIP2 | 1397 | 5 | 3 | 35 | |
| GSE46452 | CRIP2 | 1397 | 18 | 4 | 37 | |
| GSE47630 | CRIP2 | 1397 | 10 | 10 | 20 | |
| GSE54993 | CRIP2 | 1397 | 4 | 11 | 55 | |
| GSE54994 | CRIP2 | 1397 | 21 | 4 | 28 | |
| GSE60625 | CRIP2 | 1397 | 0 | 2 | 9 | |
| GSE74703 | CRIP2 | 1397 | 4 | 3 | 29 | |
| GSE74704 | CRIP2 | 1397 | 5 | 2 | 13 | |
| TCGA | CRIP2 | 1397 | 31 | 18 | 47 |
Total number of gains: 119; Total number of losses: 62; Total Number of normals: 307.
Somatic mutations of CRIP2:
Generating mutation plots.
Highly correlated genes for CRIP2:
Showing top 20/808 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRIP2 | PRSS33 | 0.755113 | 3 | 0 | 3 |
| CRIP2 | CYP21A2 | 0.697663 | 3 | 0 | 3 |
| CRIP2 | MIR4755 | 0.697646 | 4 | 0 | 4 |
| CRIP2 | CNN3 | 0.696347 | 8 | 0 | 8 |
| CRIP2 | SMDT1 | 0.693711 | 3 | 0 | 3 |
| CRIP2 | GPR146 | 0.692545 | 3 | 0 | 3 |
| CRIP2 | LRFN5 | 0.690516 | 4 | 0 | 4 |
| CRIP2 | CLEC3B | 0.678594 | 3 | 0 | 3 |
| CRIP2 | KLHL30 | 0.676985 | 3 | 0 | 3 |
| CRIP2 | CITED2 | 0.674631 | 10 | 0 | 10 |
| CRIP2 | GIPC2 | 0.665552 | 4 | 0 | 4 |
| CRIP2 | PLIN1 | 0.663022 | 3 | 0 | 3 |
| CRIP2 | ZNF287 | 0.662136 | 3 | 0 | 3 |
| CRIP2 | KCNK2 | 0.662122 | 3 | 0 | 3 |
| CRIP2 | CCL14 | 0.66189 | 3 | 0 | 3 |
| CRIP2 | LIMD1-AS1 | 0.661504 | 3 | 0 | 3 |
| CRIP2 | FAM189A2 | 0.66044 | 9 | 0 | 9 |
| CRIP2 | ITGA7 | 0.657171 | 7 | 0 | 7 |
| CRIP2 | RBPMS2 | 0.655582 | 5 | 0 | 5 |
| CRIP2 | LMBRD1 | 0.654269 | 10 | 0 | 8 |
For details and further investigation, click here
