| Full name: HemK methyltransferase family member 1 | Alias Symbol: MTQ1 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 51409 | HGNC ID: HGNC:24923 | Ensembl Gene: ENSG00000114735 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HEMK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HEMK1 | 51409 | 52159_at | -0.4974 | 0.0446 | |
| GSE20347 | HEMK1 | 51409 | 52159_at | -0.5358 | 0.0000 | |
| GSE23400 | HEMK1 | 51409 | 52159_at | -0.2489 | 0.0000 | |
| GSE26886 | HEMK1 | 51409 | 52159_at | -0.4187 | 0.0011 | |
| GSE29001 | HEMK1 | 51409 | 52159_at | -0.6479 | 0.0001 | |
| GSE38129 | HEMK1 | 51409 | 52159_at | -0.6060 | 0.0000 | |
| GSE45670 | HEMK1 | 51409 | 52159_at | -0.2384 | 0.0654 | |
| GSE53622 | HEMK1 | 51409 | 98811 | -0.1572 | 0.2190 | |
| GSE53624 | HEMK1 | 51409 | 98811 | -0.2471 | 0.0719 | |
| GSE63941 | HEMK1 | 51409 | 52159_at | -0.5188 | 0.1904 | |
| GSE77861 | HEMK1 | 51409 | 218620_s_at | -0.3383 | 0.0071 | |
| GSE97050 | HEMK1 | 51409 | A_24_P268729 | -0.1227 | 0.6212 | |
| SRP007169 | HEMK1 | 51409 | RNAseq | -0.7452 | 0.1495 | |
| SRP008496 | HEMK1 | 51409 | RNAseq | -0.9874 | 0.0069 | |
| SRP064894 | HEMK1 | 51409 | RNAseq | -0.2144 | 0.2501 | |
| SRP133303 | HEMK1 | 51409 | RNAseq | -0.7322 | 0.0000 | |
| SRP159526 | HEMK1 | 51409 | RNAseq | -0.6377 | 0.0012 | |
| SRP193095 | HEMK1 | 51409 | RNAseq | -0.3017 | 0.0337 | |
| SRP219564 | HEMK1 | 51409 | RNAseq | -0.4621 | 0.1778 | |
| TCGA | HEMK1 | 51409 | RNAseq | -0.4344 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HEMK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HEMK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HEMK1 | 51409 | 0 | 18 | 12 | |
| GSE20123 | HEMK1 | 51409 | 0 | 19 | 11 | |
| GSE43470 | HEMK1 | 51409 | 0 | 19 | 24 | |
| GSE46452 | HEMK1 | 51409 | 2 | 16 | 41 | |
| GSE47630 | HEMK1 | 51409 | 1 | 24 | 15 | |
| GSE54993 | HEMK1 | 51409 | 6 | 2 | 62 | |
| GSE54994 | HEMK1 | 51409 | 0 | 34 | 19 | |
| GSE60625 | HEMK1 | 51409 | 5 | 0 | 6 | |
| GSE74703 | HEMK1 | 51409 | 0 | 15 | 21 | |
| GSE74704 | HEMK1 | 51409 | 0 | 12 | 8 | |
| TCGA | HEMK1 | 51409 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of HEMK1:
Generating mutation plots.
Highly correlated genes for HEMK1:
Showing top 20/1183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HEMK1 | RNF185 | 0.77511 | 3 | 0 | 3 |
| HEMK1 | TMCO4 | 0.77182 | 3 | 0 | 3 |
| HEMK1 | UBE2F | 0.771434 | 3 | 0 | 3 |
| HEMK1 | ABLIM2 | 0.762388 | 3 | 0 | 3 |
| HEMK1 | SPTLC3 | 0.761569 | 3 | 0 | 3 |
| HEMK1 | FBXW5 | 0.753221 | 3 | 0 | 3 |
| HEMK1 | ATP13A4 | 0.751244 | 3 | 0 | 3 |
| HEMK1 | KDM5D | 0.750243 | 3 | 0 | 3 |
| HEMK1 | NIPSNAP3A | 0.747421 | 5 | 0 | 5 |
| HEMK1 | TSPAN5 | 0.744634 | 3 | 0 | 3 |
| HEMK1 | PRADC1 | 0.74161 | 3 | 0 | 3 |
| HEMK1 | GPD1L | 0.74043 | 9 | 0 | 9 |
| HEMK1 | SH3PXD2A-AS1 | 0.737419 | 3 | 0 | 3 |
| HEMK1 | LNPEP | 0.732539 | 4 | 0 | 4 |
| HEMK1 | WDFY2 | 0.730201 | 3 | 0 | 3 |
| HEMK1 | MAU2 | 0.729386 | 3 | 0 | 3 |
| HEMK1 | PNPLA8 | 0.72905 | 3 | 0 | 3 |
| HEMK1 | FAM174A | 0.725336 | 4 | 0 | 4 |
| HEMK1 | TMEM129 | 0.723174 | 3 | 0 | 3 |
| HEMK1 | SLC46A2 | 0.721194 | 5 | 0 | 5 |
For details and further investigation, click here
