| Full name: zyg-11 family member B, cell cycle regulator | Alias Symbol: FLJ13456 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 79699 | HGNC ID: HGNC:25820 | Ensembl Gene: ENSG00000162378 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZYG11B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZYG11B | 79699 | 225350_s_at | -0.1395 | 0.7272 | |
| GSE26886 | ZYG11B | 79699 | 225350_s_at | -0.0233 | 0.9391 | |
| GSE45670 | ZYG11B | 79699 | 225350_s_at | -0.4550 | 0.0005 | |
| GSE53622 | ZYG11B | 79699 | 69438 | -0.4665 | 0.0000 | |
| GSE53624 | ZYG11B | 79699 | 47604 | -0.6268 | 0.0000 | |
| GSE63941 | ZYG11B | 79699 | 225350_s_at | -0.6899 | 0.0596 | |
| GSE77861 | ZYG11B | 79699 | 225350_s_at | -0.0871 | 0.7608 | |
| GSE97050 | ZYG11B | 79699 | A_23_P426140 | -0.4399 | 0.1725 | |
| SRP007169 | ZYG11B | 79699 | RNAseq | -1.1000 | 0.0006 | |
| SRP008496 | ZYG11B | 79699 | RNAseq | -0.7473 | 0.0001 | |
| SRP064894 | ZYG11B | 79699 | RNAseq | -0.3141 | 0.0404 | |
| SRP133303 | ZYG11B | 79699 | RNAseq | -0.0017 | 0.9885 | |
| SRP159526 | ZYG11B | 79699 | RNAseq | -0.3141 | 0.1584 | |
| SRP193095 | ZYG11B | 79699 | RNAseq | -0.3856 | 0.0000 | |
| SRP219564 | ZYG11B | 79699 | RNAseq | -0.1800 | 0.4615 | |
| TCGA | ZYG11B | 79699 | RNAseq | -0.1272 | 0.0074 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZYG11B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZYG11B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZYG11B | 79699 | 3 | 4 | 23 | |
| GSE20123 | ZYG11B | 79699 | 3 | 3 | 24 | |
| GSE43470 | ZYG11B | 79699 | 5 | 2 | 36 | |
| GSE46452 | ZYG11B | 79699 | 2 | 1 | 56 | |
| GSE47630 | ZYG11B | 79699 | 8 | 4 | 28 | |
| GSE54993 | ZYG11B | 79699 | 0 | 1 | 69 | |
| GSE54994 | ZYG11B | 79699 | 11 | 2 | 40 | |
| GSE60625 | ZYG11B | 79699 | 0 | 0 | 11 | |
| GSE74703 | ZYG11B | 79699 | 4 | 1 | 31 | |
| GSE74704 | ZYG11B | 79699 | 2 | 0 | 18 | |
| TCGA | ZYG11B | 79699 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 36; Total Number of normals: 404.
Somatic mutations of ZYG11B:
Generating mutation plots.
Highly correlated genes for ZYG11B:
Showing top 20/772 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZYG11B | BBIP1 | 0.779704 | 3 | 0 | 3 |
| ZYG11B | RPL14 | 0.752958 | 3 | 0 | 3 |
| ZYG11B | GAPVD1 | 0.738308 | 3 | 0 | 3 |
| ZYG11B | N4BP2L1 | 0.734846 | 3 | 0 | 3 |
| ZYG11B | ZRANB1 | 0.730997 | 3 | 0 | 3 |
| ZYG11B | KPNA3 | 0.730793 | 4 | 0 | 4 |
| ZYG11B | IFT81 | 0.729564 | 3 | 0 | 3 |
| ZYG11B | CREBBP | 0.725967 | 4 | 0 | 4 |
| ZYG11B | ARIH2 | 0.724825 | 3 | 0 | 3 |
| ZYG11B | HOXA4 | 0.724591 | 3 | 0 | 3 |
| ZYG11B | PDLIM2 | 0.723128 | 3 | 0 | 3 |
| ZYG11B | CUL1 | 0.718862 | 3 | 0 | 3 |
| ZYG11B | SPTBN1 | 0.717664 | 3 | 0 | 3 |
| ZYG11B | FAM8A1 | 0.717264 | 4 | 0 | 4 |
| ZYG11B | PRKAB1 | 0.705762 | 4 | 0 | 4 |
| ZYG11B | CALCOCO2 | 0.705024 | 4 | 0 | 4 |
| ZYG11B | HECA | 0.704782 | 4 | 0 | 4 |
| ZYG11B | FBXO3 | 0.70456 | 3 | 0 | 3 |
| ZYG11B | GPRASP2 | 0.701151 | 3 | 0 | 3 |
| ZYG11B | SACS | 0.699957 | 3 | 0 | 3 |
For details and further investigation, click here
